Results 101 to 110 of about 63,943 (301)

Extracellular adenine nucleotides inhibit the release of major monocyte recruiters by human monocyte-derived dendritic cells.

, 2006
Extracellular ATP is known to affect the maturation of monocyte-derived dendritic cells mainly by regulation of cytokines and costimulatory molecules.
Michael Horckmans, Horckmans, Michael, Parmentier, Marc, Marteau, Frédéric, Frédéric Marteau, Marc Parmentier, Bulté, Frédéric, Communi, Didier, Didier Communi, Jean-Marie Boeynaems, Marcet, Brice, Arielle Maho, Boeynaems, Jean-Marie, Brice Marcet, Frédéric Bulté, Maho, Arielle   +15 more
core   +1 more source

Protein‐Independent Liquid–Liquid Phase Separation of Adenosine Triphosphate Under Crowded Conditions

Chemistry – A European Journal, EarlyView.
ATP itself is able to undergo liquid–liquid phase separation in the presence of the macromolecular crowding agent PEG and physiological ATP concentrations are sufficient for phase separation in the presence of mM Mg2+ and crowders, mimicking intracellular conditions.
Robert Dec, Wojciech Dzwolak, Roland Winter   +2 more
wiley   +1 more source

Stimulation of DNA synthesis in Jurkat cells by synergistic action between adenine and guanine nucleotides

, 1991
P2-purinoceptor agonists stimulated the DNA synthesis of Jurkat cells via a pathway independent of cAMP and intracellular free calcium. The response was greatly enhanced by the synergistic action between adenine and guanine nucleotides, suggesting that ...
Nomura, Yasuyuki, Yukiko Tokumitsu, Yoshiki Yanagawa, Yanagawa, Yoshiki, Yasuyuki Nomura, Tokumitsu, Yukiko   +5 more
core   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

A single nucleotide polymorphism produces different transcription profiles in Campylobacter jejuni’s cysM

Frontiers in Microbiology
A single nucleotide polymorphism (SNP) in the 126 bp untranslated region (UTR) directly upstream of Campylobacter jejuni’s cysM (cysteine synthase) results in significant effects on gene transcription.
Nereus W. Gunther IV, Siddhartha Kanrar, Aisha Abdul-Wakeel, Michael J. McAnulty, John Renye, Joseph Uknalis, Gaylen A. Uhlich   +6 more
doaj   +1 more source

Reversal of procaine conduction blockade by adenine nucleotides in vivo and in vitro.

, 1982
The effect of the adenine nucleotides on procaine-induced conduction block in rats was investigated in vivo and in vitro. Both adenine and cyclic nucleotides significantly shortened the duration of sciatic nerve blocks in rats without affecting the ...
Gintautas, J, Kraynack, B J
core  

Influence of a fluorobenzene nucleobase analogue on the conformational flexibility of RNA studied by molecular dynamics simulations

, 2006
Chemically modified bases are frequently used to stabilize nucleic acids, to study the driving forces for nucleic acid structure formation and to tune DNA and RNA hybridization conditions.
Zacharias, Martin, Engels, Joachim W. (Prof. Dr.)   +1 more
core   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Effects of adenosine and adenine nucleotides on synaptic transmission in the cerebral cortex

, 1979
Adenosine and the adenine nucleotides have a potent depressant action on cerebral cortical neurons, including identified corticospinal cells. Other purine and pyrrolidine nucleotides were either weakly depressant (inosine and guanosine derivatives) or ...
J. W. Phillis, J. R. Kirkpatrick, G. K. Kostopoulos, J. P. Edstrom   +3 more
core   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source