Results 1 to 10 of about 497,572 (167)

CTP Synthase 2 From Arabidopsis thaliana Is Required for Complete Embryo Development

Frontiers in Plant Science, 2021
Pyrimidine de novo synthesis is an essential pathway in all organisms. The final and rate-limiting step in the synthesis of the nucleotide cytidine triphosphate (CTP) is catalyzed by CTP synthase (CTPS), and Arabidopsis harbors five isoforms.
Daniel Hickl, David Scheuring, Torsten Möhlmann   +2 more
doaj   +1 more source

Integrated Multi-Omics Analysis for Inferring Molecular Players in Inclusion Body Myositis

Antioxidants, 2023
Inclusion body myositis (IBM) is an acquired inflammatory myopathy affecting proximal and distal muscles that leads to weakness in patients over 50.
Judith Cantó-Santos, Laura Valls-Roca, Ester Tobías, Clara Oliva, Francesc Josep García-García, Mariona Guitart-Mampel, Félix Andújar-Sánchez, Anna Esteve-Codina, Beatriz Martín-Mur, Joan Padrosa, Raquel Aránega, Pedro J. Moreno-Lozano, José César Milisenda, Rafael Artuch, Josep M. Grau-Junyent, Glòria Garrabou   +15 more
doaj   +1 more source

Oncogenic Integration of Nucleotide Metabolism via Fatty Acid Synthase in Non-Hodgkin Lymphoma

Frontiers in Oncology, 2021
Metabolic dysfunctions enabling increased nucleotide biosynthesis are necessary for supporting malignant proliferation. Our investigations indicate that upregulation of fatty acid synthase (FASN) and de novo lipogenesis, commonly observed in many cancers,
Dashnamoorthy Ravi, Dashnamoorthy Ravi, Afshin Beheshti, Afshin Beheshti, Nasséra Abermil, Frederick Lansigan, Frederick Lansigan, William Kinlaw, Nirupa R. Matthan, Maisarah Mokhtar, Frank C. Passero, Patrick Puliti, Patrick Puliti, Patrick Puliti, Kevin A. David, Kevin A. David, Gregory G. Dolnikowski, Xiaoyang Su, Xiaoyang Su, Ying Chen, Mahboubi Bijan, Rohan R. Varshney, Baek Kim, Baek Kim, Sandeep S. Dave, Michael C. Rudolph, Andrew M. Evens, Andrew M. Evens   +27 more
doaj   +1 more source

Protein Mass and Calcium Mass of Broiler Chicken with Added Nucleotides at Different Maintenance Temperatures

Jurnal Sain Peternakan Indonesia, 2021
This study aims to examine the effect of adding nucleotides in broiler rations on the protein mass and calcium mass of broiler chicken reared at different temperatures.
I. Rahmawati, L .D. Mahfudz, S. Kismiati
doaj   +1 more source

Dietary Supplementation of Brown Seaweed and/or Nucleotides Improved Shrimp Performance, Health Status and Cold-Tolerant Gene Expression of Juvenile Whiteleg Shrimp during the Winter Season

Marine Drugs, 2021
This study was aimed to evaluate the efficiency of Sargassumpolycystum and nucleotides- supplemented diets to improve immune response and cold-tolerance of juvenile Litopenaeus vannamei.
Mohamed Abdel-Rahim, Omar Bahattab, Fatma Nossir, Yahya Al-Awthan, Riad H. Khalil, Radi Mohamed   +5 more
doaj   +1 more source

Physiological and Metabolic Responses of Leymus chinensis Seedlings to Alkali Stress

Plants, 2022
To elucidate the physiological and metabolic mechanism of perennial grass responses to alkali stress, we selected Leymus chinensis (L. chinensis), a salt-tolerant perennial rhizomatous species of the family Poaceae as experimental material.
Ge Yan, Yujie Shi, Fangfang Chen, Chunsheng Mu, Junfeng Wang   +4 more
doaj   +1 more source

Effect of Deep Dormancy Temperature Cultivation on Meat Quality of Crucian Carp (Carassius auratus)

Foods, 2023
To extend the survival of crucian carp (Carassius auratus) during transportation, the effect of deep dormancy temperature (DDT) cultivation on the crucian carp was investigated by measuring the respiratory rate, survival time, and effect of cooling speed
Yin Zhang, Linguo Wang, Yunlong Mu, Qing Zeng, Jianlin Jia, Pengcheng Zhang, Zhongli Pan   +6 more
doaj   +1 more source

The First 5′-Phosphorylated 1,2,3-Triazolyl Nucleoside Analogues with Uracil and Quinazoline-2,4-Dione Moieties: A Synthesis and Antiviral Evaluation

Molecules, 2022
A series of 5′-phosphorylated (dialkyl phosphates, diaryl phosphates, phosphoramidates, H-phosphonates, phosphates) 1,2,3-triazolyl nucleoside analogues in which the 1,2,3-triazole-4-yl-β-D-ribofuranose fragment is attached via a methylene group or a ...
Dmitry A. Tatarinov, Bulat F. Garifullin, Mayya G. Belenok, Olga V. Andreeva, Irina Yu Strobykina, Anna V. Shepelina, Vladimir V. Zarubaev, Alexander V. Slita, Alexandrina S. Volobueva, Liliya F. Saifina, Marina M. Shulaeva, Vyacheslav E. Semenov, Vladimir E. Kataev   +12 more
doaj   +1 more source

Purine Nucleotides in the Regulation of Brown Adipose Tissue Activity

Frontiers in Endocrinology, 2020
Non-shivering thermogenesis in mammalian brown adipose tissue is a powerful mechanism to defend normothermia in cold climates. To minimize the loss of chemical energy, the central functional component, mitochondrial uncoupling protein 1, UCP1, must be ...
Andrea Bast-Habersbrunner, Andrea Bast-Habersbrunner, Tobias Fromme, Tobias Fromme   +3 more
doaj   +1 more source

Improvement in RNA extraction from S. cerevisie by optimization in the autolysis and NH3 hydrolysis

Brazilian Archives of Biology and Technology, 2011
The optimization of autolysis of Saccharomyces cerevisiae from brewery was studied aiming at the maximum ribonucleic acid extraction and yeast extract production.
Antonio Martins Oliveira, Pedro de Oliva Neto   +1 more
doaj   +1 more source