Results 31 to 40 of about 551,715 (314)

New Strategy to Preserve Phosphate by Ionic Liquid Matrices in Matrix-Assisted Laser Desorption/Ionization: A Case of Adenosine Nucleotides

open access: yesMolecules, 2020
Adenosine -5′-triphosphate (ATP) plays a valuable role in metabolic activity to produce adequate energy in a biosystem. A high ATP/AMP ratio has a correlation with diabetes that induces suppression of AMP-activated protein kinase (AMPK).
Chih-Hao Lin   +3 more
doaj   +1 more source

The evolution of nucleotides

open access: yesAdvances in Space Research, 1986
There has been much speculation about the types of molecules that were present in the first living forms. Recent discoveries show that RNA is a more versatile molecule than was previously believed, but whether it was ever able, for example, to synthesize its own monomers from available precursors is not yet known.
D A, Usher, M C, Needels
openaire   +2 more sources

Red Blood Cell Adenylate Energetics Is Related to Endothelial and Microvascular Function in Long COVID

open access: yesBiomedicines
Adenine nucleotides play a critical role in maintaining essential functions of red blood cells (RBCs), including energy metabolism, redox status, shape fluctuations and RBC-dependent endothelial and microvascular functions.
Marzena Romanowska-Kocejko   +9 more
doaj   +1 more source

Kappa casein gen (CSN3) in horse: genetic variability in exon 1 and 4

open access: yesActa Agriculturae Slovenica, 2006
Kappa casein (κ-CN) is milk protein that determines the size and specific function of the casein micelles, and its clevage by chymosine is responsible for milk coagulation.
Sebastijan HOBOR   +3 more
doaj   +1 more source

HPLC analysis of nucleotides

open access: yes, 2017
This project developed a novel hydrophilic interaction chromatography method for the detection and identification of nucleotides. The method was validated by testing biological specimens; adult and neonatal saliva, and red and white blood cell extracts ...
Narayan, Vicrant S.
core   +1 more source

Processes Underlining the Action of Pesticides on Ecosystems and Human Organism

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2017
This article is devoted to the study of the mechanism of action of pesticides as compounds with a high complexing capacity for metals, nucleotides and enzymes.
Elena Saratovskikh
doaj   +1 more source

Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy

open access: yesPharmaceuticals, 2011
Ribonucleotide reductase (RR) is a crucial enzyme in de novo DNA synthesis, where it catalyses the rate determining step of dNTP synthesis. RRs consist of a large subunit called RR1 (α), that contains two allosteric sites and one catalytic site, and a ...
Prem Singh Kaushal   +8 more
doaj   +1 more source

Extracellular Nucleotides in the Regulation of Kidney Functions

open access: yes, 2013
ATP is normally regarded as the major source of fuel for the energy-demanding processes within cells; however, ATP and other nucleotides (such as ADP, UTP, UDP) can be released from cells, where they act as autocrine or paracrine signaling molecules to ...
Kishore, Bellamkonda   +8 more
core   +1 more source

Supplementation of Nucleotides to Enhance Performance and Immune Responses of Asian Seabass [PDF]

open access: yes, 2021
Supplementation of nucleotides into fish diets can be an alternative method to manage disease problems in aquaculture, since it was reported could improve the growth rate and immunity of some aquaculture species. The present study assessed the growth and
Glencross, Brett   +5 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy