Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]
, 2012 Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz +60 more
core +2 more sources
Enzyme-free genetic copying of DNA and RNA sequences
Beilstein Journal of Organic Chemistry, 2018 The copying of short DNA or RNA sequences in the absence of enzymes is a fascinating reaction that has been studied in the context of prebiotic chemistry.
Marilyne Sosson, Clemens Richert
doaj +1 more source
Effect of Deep Dormancy Temperature Cultivation on Meat Quality of Crucian Carp (Carassius auratus)
Foods, 2023 To extend the survival of crucian carp (Carassius auratus) during transportation, the effect of deep dormancy temperature (DDT) cultivation on the crucian carp was investigated by measuring the respiratory rate, survival time, and effect of cooling speed
Yin Zhang +6 more
doaj +1 more source
Relationship between promoter sequence and its strength in gene expression
, 2014 In this study, through various tests one theoretical model is presented to describe the relationship between promoter strength and its nucleotide sequence.
Li, Jingwei, Zhang, Yunxin
core +1 more source
Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch [PDF]
, 2006 Riboswitches are highly structured elements in the 50-untranslated regions (50-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and
Noeske, Jonas +5 more
core +1 more source
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis
Journal of Lipid ResearchA key organismal response to overnutrition involves the development of new adipocytes through the process of adipogenesis. Preadipocytes sense changes in the systemic nutrient status and metabolites can directly modulate adipogenesis.
Julia A. Pinette +16 more
doaj +1 more source
Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor. [PDF]
, 2018 ATP-powered viral packaging motors are among the most powerful biomotors known. Motor subunits arranged in a ring repeatedly grip and translocate the DNA to package viral genomes into capsids.
Alam, Istiaq +4 more
core +3 more sources
Effect of nucleotides on broiler performance and carcass yield
Brazilian Journal of Poultry Science, 2010 This study aimed at evaluating the effect of nucleotides on the performance and carcass yield of broilers fed diets with no antibiotic growth promoters (AGP), anticoccidials, or animal feedstuffs. In the trial, 600 Ross 308 male broilers were distributed
VC Pelícia +7 more
doaj +1 more source
Thermophilic phosphoribosyltransferases Thermus thermophilus HB27 in nucleotide synthesis
Beilstein Journal of Organic Chemistry, 2018 Phosphoribosyltransferases are the tools that allow the synthesis of nucleotide analogues using multi-enzymatic cascades. The recombinant adenine phosphoribosyltransferase (TthAPRT) and hypoxanthine phosphoribosyltransferase (TthHPRT) from Thermus ...
Ilja V. Fateev +9 more
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source