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An Sp1 Modulated Regulatory Region Unique to Higher Primates Regulates Human Androgen Receptor Promoter Activity in Prostate Cancer Cells [PDF]
, 2015 Funding: This work was supported by the Chief Scientist’s Office (CSO) of the Scottish Government (http://www.cso.scot.nhs.uk/): CWH (CZB-4-477) and IH (ETM/382).Peer reviewedPublisher ...
Hay, Colin W +3 more
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Biomolecules, 2023 Ribosomal frameshifting (RFS) at the slippery site of SARS-CoV-2 RNA is essential for the biosynthesis of the viral replication machinery. It requires the formation of a pseudoknot (PK) structure near the slippery site and can be inhibited by PK ...
Ekaterina Knizhnik +11 more
doaj +1 more source
The Two Faces of the Guanyl Radical: Molecular Context and Behavior
Molecules, 2021 The guanyl radical or neutral guanine radical G(-H)• results from the loss of a hydrogen atom (H•) or an electron/proton (e–/H+) couple from the guanine structures (G). The guanyl radical exists in two tautomeric forms.
Chryssostomos Chatgilialoglu
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Nanoparticles-Based Oligonucleotides Delivery in Cancer: Role of Zebrafish as Animal Model
Pharmaceutics, 2021 Oligonucleotide (ON) therapeutics are molecular target agents composed of chemically synthesized DNA or RNA molecules capable of inhibiting gene expression or protein function.
Sara Bozzer +4 more
doaj +1 more source
Dendriplex-Impregnated Hydrogels With Programmed Release Rate
Frontiers in Chemistry, 2022 Hydrogels are biocompatible matrices for local delivery of nucleic acids; however, functional dopants are required to provide efficient delivery into cells. In particular, dendrimers, known as robust nucleic acid carriers, can be used as dopants. Herein,
Evgeny Apartsin +8 more
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Проблемы особо опасных инфекций, 2020 Objective of the study is to analyze the genetic markers of tick-borne encephalitis virus, which can be used to specifically indicate the maximum number of virus strains and isolates.Materials and methods.
N. I. Khammadov
doaj +1 more source
Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical Ligation
Frontiers in Chemistry, 2021 Cell penetrating peptides (CPPs) are being increasingly used as efficient vectors for intracellular delivery of biologically active agents, such as therapeutic antisense oligonucleotides (ASOs).
Mohadeseh Dastpeyman +5 more
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Diamonds for Life: Developments in Sensors for Biomolecules
Applied Sciences, 2022 Diamond-based electrodes and biosensors are interesting in analytics because of their particular set of properties, namely: large potential window, chemical inertness, low baseline current, stability, and transparency.
Nádia E. Santos +5 more
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Cells, 2023 Interleukin-6 (IL-6) is a pleiotropic cytokine that plays a crucial role in maintaining normal homeostatic processes under the pathogenesis of various inflammatory and autoimmune diseases.
Dhanu Gupta +6 more
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Plant Methods, 2017 Background The complex cell wall structure of algae often precludes efficient extraction of their genetic material. The purpose of this study was to design a next-generation sequencing-suitable DNA isolation method for unicellular, achlorophyllous, yeast-
Tomasz Jagielski +5 more
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