Angewandte Chemie International Edition, 2011 DNA as an information storage system is simple and at the same time complex owing to the various different arrangements of the four natural nucleotides.[1] The DNA synthesis by DNA polymerases is intriguing, since these enzymes are able to catalyze the elongation of the primer strand by recognizing the DNA template and selecting the corresponding ...
Baccaro, Anna +2 more
openaire +4 more sources
Kinetic and NMR spectroscopic study of the Chemical Stability and Reaction Pathways of Sugar Nucleotides [PDF]
, 2022 The alkaline cleavage of two types of sugar nucleotides has been studied by 1H and 31P NMR in order to obtain information on the stability and decomposition pathways in in aqueous solutions under alkaline conditions.
Korhonen Heidi +5 more
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Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]
, 2012 Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Claire M. Peppiatt-Wildman +18 more
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Assessment of the palatability of Atlantic salmon by NMR spectroscopy
Пищевые системы, 2023 H-NMR spectroscopy was used to study the metabolic profile of Atlantic salmon muscle tissue during heat treatment and storage to assess the taste of products. It has been established that when steaming fish, the amount of compounds such as trimethylamine
L. S. Abramova +3 more
doaj +1 more source
Guanosine nucleotides regulate B2 kinin receptor affinity of agonists but not of antagonists: Discussion of a model proposing receptor precoupling to G protein [PDF]
, 2000 The effect of nucleotides on binding of the B2 kinin (BK) receptor agonist {[}H-3]BK and the antagonist {[}H-3]NPC17731 to particulate fractions of human foreskin fibroblasts was studied.
Er Faussner +3 more
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Survey of ribose ring pucker of signaling nucleosides and nucleotides [PDF]
, 2020 The ribose of protein-bound nucleosides and nucleotides displays preferred conformations (usually either North or South), which can be exploited to design enhanced analogs having chemically fixed conformations.
Jacobson K. A., Salmaso V.
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Comparison of nonvolatile taste components in 18 strong fragrance spices
International Journal of Food Properties, 2020 In order to investigate the taste compounds of 18 strong fragrance spices, high performance liquid chromatography was used to determine the content of free amino acids, nucleotides and organic acids.
Wen Duan +4 more
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RNA polymerisation without catalyst from 2’,3’-cyclic nucleotides by drying at air-water interfaces
, 2022 For the emergence of life, the abiotic synthesis of RNA from its monomers is a central step. We found alkaline, uncatalysed drying conditions in bulk and at heated air-water interfaces where 2´,3´-cyclic nucleotides polymerised, forming up to 10-mers ...
Sreekar, Wunnava +16 more
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Nutritional Modulation of the Immune Response Mediated by Nucleotides in Canine Leishmaniosis
Microorganisms, 2021 Leishmaniasis is an emerging, uncontrolled, and neglected zoonotic disease. Climate change is contributing to its ongoing global expansion. The dog is the main reservoir; hence the importance of implementing effective treatment, prevention, and control ...
Sergi Segarra
doaj +1 more source
CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis. [PDF]
, 2012 The cyclic nucleotides cyclic adenosine-3',5'-monophosphate (cAMP) and cyclic guanosine-3',5'-monophosphate (cGMP) are important second messengers and are potential biomarkers for Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and ...
Oeckl, Patrick +23 more
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