Results 181 to 190 of about 644,554 (330)

Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides.

open access: yesJournal of Clinical Investigation, 1998
Lance Morabito   +8 more
semanticscholar   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

Control of Choline Oxidation in Liver Mitochondria by Adenine Nucleotides

open access: hybrid, 1965
Tsuneo Kagawa   +2 more
openalex   +1 more source

Reagentless Real‐Time ATP Monitoring with New DNA Aptamers

open access: yesSmall, EarlyView.
A new aptamer is discovered via in vitro selection that binds to adenosine triphosphate (ATP) with high affinity (KD = 0.7 µm) and rejects closely related analogs including adenosine diphosphate (ADP), adenosine monophosphate (AMP), and adenosine. A fluorescent molecular beacon based on the aptamer enables continuous analyte monitoring in cell culture ...
Adara Bacon   +5 more
wiley   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

open access: yesSmall Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu   +6 more
wiley   +1 more source

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