The Role of Magnesium in Liver Cirrhosis
Magnesium is a vital mineral involved in over 300 enzymatic reactions, crucial for physiological functions. Its deficiency, common in liver cirrhosis patients, correlates with poor outcomes by affecting inflammation, oxidative stress, fibrosis, and immunity. This review explores magnesium's role in cirrhosis and its interaction with disease mechanisms.
Weiye Zeng+4 more
wiley +1 more source
Control of Choline Oxidation in Liver Mitochondria by Adenine Nucleotides
Tsuneo Kagawa+2 more
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Secretory mechanisms. Behaviour of adenine nucleotides during the platelet release reaction induced by adenosine diphosphate and adrenaline [PDF]
Holm Holmsen+2 more
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ABSTRACT ZraS is a metal sensor integral to ZraPSR, a two‐component signaling system found in enterobacters. It belongs to a family of bifunctional sensor histidine kinases (SHKs) and is speculated to sense zinc‐induced stress on the bacterial envelope.
Nilima Mahapatra+3 more
wiley +1 more source
The role of selection pressure in shaping zoxamide resistance in Plasmopara viticola populations
Zoxamide resistance management in Plasmopara viticola: controlling selection pressure through optimal fungicide application frequency to reduce the spread of resistant strains possessing different point mutations associated with resistance. Abstract BACKGROUND Zoxamide, a β‐tubulin inhibitor, is widely used in vineyards to control downy mildew caused ...
Mattia Peracchi+4 more
wiley +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa+4 more
wiley +1 more source
Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos+2 more
wiley +1 more source
MondoA senses adenine nucleotides: transcriptional induction of thioredoxin-interacting protein. [PDF]
Han KS, Ayer DE.
europepmc +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu+6 more
wiley +1 more source
Alterations in nicotinamide and adenine nucleotide systems during mixed-function oxidation of p-nitroanisole in perfused livers from normal and phenobarbital-treated rats [PDF]
Frederick C. Kauffman+2 more
openalex +1 more source