Results 211 to 220 of about 118,017 (284)

The oncogenic control of nucleotide synthesis. [PDF]

Oncogenesis
Vidal-Cruchez O, Ben-Sahra I.
europepmc   +1 more source

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

The Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana, Collin Matsumoto, L. Fernando Santana   +2 more
wiley   +1 more source

A Comparative Study for the Incorporation of 8-oxo-dATP in DNA by Human DNA Polymerases. [PDF]

Int J Mol Sci
Kruchinin AA, Kamzeeva PN, Baranov MS, Belova YG, Boldinova EO, Baranovskiy AG, Tahirov TH, Aralov AV, Makarova AV.   +8 more
europepmc   +1 more source

Seasonal shifts in mitochondrial and reactive oxygen species metabolism are linked to ultrastructural remodelling in honey bees (Apis mellifera)

The Journal of Physiology, EarlyView.
Abstract figure legend Seasonal changes profoundly reshape honey bee mitochondrial metabolism. In winter, bees shift from complex I (CI)‐ to mitochondrial glycerol‐3‐phosphate dehydrogenase (mG3PDH)‐ and complex II (CII)‐linked respiration. Despite lower CI‐linked respiration ATP production is maintained, suggesting increased energetic efficiency in ...
Adèle Léger, Mélanie Aminot, Samuel Robichaud, Sarah Jorissen, Étienne Hébert‐Chatelain, Nicolas Pichaud   +5 more
wiley   +1 more source

High-throughput analyses of a reconstituted diversity-generating retroelement identify intrinsic and extrinsic determinants of diversification. [PDF]

PLoS Genet
Unlu I, Smiley MK, Potapov V, Renoux-Martin Y, Sun ZY, Lim HC.   +5 more
europepmc   +1 more source

Technologies for engineering repetitive DNA

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

Targeting opportunities presented by the pyrimidine biosynthesis pathway in Mycobacterium tuberculosis: a brief review. [PDF]

Biochem Soc Trans
Alberti M, Miggiano R.
europepmc   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Late-stage adenine N6-alkylation of nucleos(t)ides and oligonucleotides via photoredox and copper co-catalytic decarboxylative C(sp3)-N coupling. [PDF]

Nat Commun
Xie R, Xiao G, Li W, Luochen W, Butt M, Que Y, Li X, Li Y, Sun L, Chen G.   +9 more
europepmc   +1 more source

Turning up the heat: Can thermal therapy really protect muscle health in older adults?

Experimental Physiology, EarlyView.
Franck Brocherie, Yohan Rousse, Grégoire P. Millet   +2 more
wiley   +1 more source