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Receptors for adenosine and adenine nucleotides
General Pharmacology: The Vascular System, 19911. A summary is provided of current classifications of receptors for the adenine nucleosides and nucleotides. 2. The origin of the division of nucleoside (P1) and nucleotide (P2) receptors is discussed as well as the subdivisions of these into A1 and A2, determined by structure activity considerations, and P2x and P2y. 3.
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Engineering a precise adenine base editor with minimal bystander editing
Nature Chemical Biology, 2022Liang Chen +23 more
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The adenine nucleotide translocator and the nucleotide specificity of oxidative phosphorylation
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1970Abstract By studying P/O ratios, proton translocation and morphology of different mitochondrial preparations, it was shown, in agreement with previous work but in disagreement with a recent report, that the nucleotide specificity of the oxidative phosphorylation resides at the level of the adenine nucleotide translocator.
J.H.M. Souverijn +3 more
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Measurement of Adenine Nucleotides
1975Classically the autonomic nervous system consists of two components, adrenergic and cholinergic nerves. There have been a number of reports of a third nerve component in the autonomic nervous system which is neither adrenergic nor cholinergic and evidence has been presented that the transmitter released from these nerves, at least in the ...
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Effect of adenine nucleotides on reactions involving triphosphopyridine nucleotide
Biochimica et Biophysica Acta, 1955Oxidized TPN, and P-ADPR have been found to be competitive inhibitors of the TPNH-cytochrome c reductase of horse liver. 2′ AMP also competitively inhibits, at somewhat higher concentrations. DPN, ADPR, desamino TPN, 3′ AMP, 5′ AMP, 2′ IMP, and 3′ IMP produce very slight or no inhibition.
Elizabeth F. Neufeld +2 more
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Effects of Adenine Nucleotides on Renal Metabolism
Nephron, 1969Regulatory effects which adenine nucleotides are known to exert on glycolysis and gluconeogenesis have been demonstrated in the isolated perfused rat kidney and in kidney cortex slices.
H.A. Krebs, D. A. Hems, M.J. Weidemann
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Discovery of a natural thiamine adenine nucleotide
Nature Chemical Biology, 2007Several important cofactors are adenine nucleotides with a vitamin as the catalytic moiety. Here, we report the discovery of the first adenine nucleotide containing vitamin B1: adenosine thiamine triphosphate (AThTP, 1), or thiaminylated ATP. We discovered AThTP in Escherichia coli and found that it accumulates specifically in response to carbon ...
Tiziana Gigliobianco +9 more
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Adenine nucleotide degradation in the rabbit heart
American Journal of Physiology-Legacy Content, 1964Adenine nucleotide analysis of tissue and perfusates of the isolated rabbit heart were undertaken following hypoxia and uncoupled oxidative phosphorylation. During uncoupled oxidative phosphorylation, nucleotide degradation, primarily that of ATP, was three times as great as that observed during hypoxia.
Leigh Wyborny, Harold G. Richman
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Adenosine and Adenine Nucleotides As Regulators of Cellular Function
, 1991INTRODUCTION. Historical Perspectives-Adenosine (D.J. Cushing and S.J. Mustafa). Historical Perspectives-ATP (D. Satchell). PURINE RECEPTORS, METABOLISM, RELEASE, AND TRANSPORT. Adenosine Receptors: Ligand-Binding Studies (U. Schwabe).
J. Phillis
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Regeneration of Adenine Nucleotides in the Heart
1988The fast adenine nucleotide degradation, which takes place in the ischemic heart, contrasts with the slow regeneration after ischemia.
J. W. de Jong, P. van der Meer
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