Results 131 to 140 of about 57,312 (301)

Enhancement of immune checkpoint inhibitor efficacy by DHX58+ SELL+ T cells in advanced gastric cancer

VIEW, EarlyView.
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen, Youdong Liu, Hongda Pan, Tianyi Cai, Mingde Zang, Xiaowen Liu, Ziwen Long, Xin Fan, Jun Lu, Fenglin Liu   +9 more
wiley   +1 more source

Relationship Between Radiographic and Pathological Portal Vein‐Superior Mesenteric Vein Involvement in Neoadjuvant Treatment for Pancreatic Cancer: A Comparative Study of Neoadjuvant Chemotherapy and Chemoradiotherapy

World Journal of Surgery, EarlyView.
The relationship between the radiographic portal vein‐superior mesenteric vein (PV‐SMV) involvement and pathological PV‐SMV (pPV) invasion has been established in upfront surgery cases of pancreatic cancer (PC); however, evidence remains limited for patients receiving neoadjuvant therapy (NAT).
Naoko Sekiguchi, Hidenori Takahashi, Hirofumi Akita, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Tadafumi Asaoka, Takehiro Noda, Junzo Shimizu, Shogo Kobayashi, Yuichiro Doki, Hidetoshi Eguchi   +13 more
wiley   +1 more source

Contemporary Analysis of VTE Risk After HPB Surgery: 2517 Consecutive Patients Treated With Extended Chemoprophylaxis

World Journal of Surgery, EarlyView.
Independent predictors of Venous Thromboembolism (VTE) within the first 45 post‐operative days on multivariate analyses.
Anish J. Jain, Esther N. Dekker, Laura Prakash, Elsa M. Arvide, Yi‐Ju Chiang, Rebecca A. Snyder, Matthew H. G. Katz, Ching‐Wei D. Tzeng   +7 more
wiley   +1 more source

Development and Validation of an Individualized Nomogram to Identify Undifferentiated‐Predominant Mixed‐Type Early Gastric Cancer

Journal of Digestive Diseases, EarlyView.
This study identified open‐type atrophic gastritis, flat or depressed morphology, faded appearance, tumor location on the greater curvature or anterior wall, xanthoma, and previous Helicobacter pylori eradication as independent risk factors for undifferentiated‐type‐predominant mixed‐type early gastric cancer (UM‐EGC).
Lin Lin Shao, Yu Miao Zheng, Qian Zhang, Chuan Guo Guo, Peng Li   +4 more
wiley   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

mpMRI features of mucinous prostate cancer: two case reports

The Egyptian Journal of Radiology and Nuclear Medicine
Background Mucinous adenocarcinoma of the prostate (MACP) is one of the rarest variants of prostatic neoplasm, with more aggressive behavior than non-mucinous prostatic cancer.
Giuseppe Chiacchio, Alessandro Grimaldi, Edoardo Beatrici, Riccardo Rossi, Simone Cappuccelli, Lucia Pitoni, Vito Lacetera, Giuliana Gabrielloni, Alberto Rebonato, Simone Scarcella, Valerio Beatrici   +10 more
doaj   +1 more source

Pancreatic Adenocarcinoma: Diagnosis by Ultrasound-Guided Fine-Needle Aspiration-Cyto-Histological Correlation and Experience at a Multidisciplinary Tertiary Reference Center. [PDF]

Diagn Cytopathol
ABSTRACT Background Pancreatic adenocarcinoma (PDAC) is characterized by its poor prognosis. Cytology is essential for diagnostic confirmation and ancillary studies. The endoscopic ultrasound (EUS) set a precedent, facilitating cytological sampling through fine‐needle aspiration (FNA), with a sensitivity of 93% and a specificity of 95%.
González-López J, Bauza ME, Pérez-Rojas J, López-Valdivia C, Romero CZ, Castells-Perona Ó, Ballester-Ibáñez C, Montalvá-Orón E, López-Andújar R, Argüello-Viudez L, Rodríguez MP.   +10 more
europepmc   +2 more sources

Surveillance After Pelvic Exenteration: A Systematic Review of Oncological and Functional Follow‐Up

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Surveillance following cancer surgery with curative intent serves the purpose of permitting early detection of recurrent disease in addition to monitoring and management of post‐resection functional sequelae. Although recommendations exist for most primary cancers, in the context of radical or re‐operative surgery such as pelvic ...
Adrian Hang Yue Siu, Konrad Joseph, Daniel Steffens, Sharon Carey, Michael Solomon, Cherry Koh   +5 more
wiley   +1 more source

What Is the Evidence Base Regarding Early Onset Colorectal Cancer in Australia and New Zealand? A Scoping Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Early onset colorectal cancer (EoCRC), commonly defined as colorectal cancer diagnosed in people under 50 years of age, is increasing in incidence in Australia and New Zealand. The underlying cause of this remains unclear, despite its growing public health importance.
Tiffany J. Cherry, Dilshan Udayasiri, Ian P. Hayes   +2 more
wiley   +1 more source

Cholangiocarcinoma in a central bearded dragon (Pogona vitticeps): A case report

Australian Veterinary Journal, EarlyView.
Cholangiocarcinoma is an uncommon malignant epithelial tumour of the biliary tract in reptiles and is rarely reported in central bearded dragons (Pogona vitticeps). This case report describes a 7‐year‐old male central bearded dragon in which a nonspecific coelomic opacity was incidentally detected during a routine clinical examination.
M Mikiewicz, K Paździor‐Czapula, I Otrocka‐Domagała   +2 more
wiley   +1 more source