Results 61 to 70 of about 43,883 (271)

A minor (<50%) signet-ring cell component associated with poor prognosis in colorectal cancer patients: a 26-year retrospective study in China.

PLoS ONE, 2015
BackgroundWe performed a retrospective study to determine the cancer-specific survival of colorectal cancer patients with a component of signet-ring cells or mucin comprising < 50% of the tumor mass.MethodsA total of 2454 patients seen in our hospital ...
Yinuo Tan, Jianfei Fu, Xiaofen Li, Jiao Yang, Mengjie Jiang, Kefeng Ding, Jinghong Xu, Jun Li, Ying Yuan   +8 more
doaj   +1 more source

Role of colectomy in the management of appendiceal tumors: a retrospective cohort study

BMC Gastroenterology, 2023
Background Appendiceal tumors represent a range of histologies that vary in behavior. Recommendations for treatment with appendectomy versus right hemicolectomy (RHC) for different tumor types are evolving and sometimes conflicting.
Victoria A. Marks, Daniel Kerekes, Samuel Butensky, Nita Ahuja, Caroline Johnson, Kiran Turaga, Sajid A. Khan   +6 more
doaj   +1 more source

An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases

Frontiers in Oncology, 2022
Background and AimsMucinous colorectal cancer has traditionally been associated with high rates of recurrence and poor long-term survival. There is limited published data on outcomes for patients undergoing liver resection for metastatic mucinous ...
Ian S. Reynolds, Ian S. Reynolds, Paul M. Cromwell, Éanna J. Ryan, Erinn McGrath, Rory Kennelly, Ronan Ryan, Niall Swan, Kieran Sheahan, Des C. Winter, Emir Hoti   +10 more
doaj   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

An insight into the driver mutations and molecular mechanisms underlying mucinous adenocarcinoma of the rectum

, 2021
Background: Mucinous adenocarcinoma of the rectum accounts for 10% of all rectal cancers and has an impaired response to neoadjuvant chemoradiotherapy and worse overall survival.
Anna Blümel (7898387), Sam E Mason (11196810), Deborah McNamara (7899677), Jochen Prehn (7895672), Emer O'Connell (7899752), Michael Fichtner (5168384), Ian Reynolds (7898183), John Burke (9860252), Darran O'Connor (7895339), Elaine Kay (7895411), Sudipto Das (7896221), James Kinross (1998157)   +11 more
core   +2 more sources

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Calcified mucinous adenocarcinoma of the stomach metastatic to the iris: a case report

Journal of Medical Case Reports, 2019
Background Gastric cancer has a wide spectrum of clinical features, imaging manifestations, and pathology. Punctate calcifications in gastric cancer are infrequent but are usually found in mucinous adenocarcinoma.
Miki Kaneko, Tadashi Namisaki, Hiroaki Takaya, Hitoshi Mori, Mitsuteru Kitade, Yasushi Okura, Kenichiro Seki, Shinya Sato, Keisuke Nakanishi, Koh Kitagawa, Takahiro Ozutsumi, Naotaka Shimozato, Kosuke Kaji, Tomoyuki Otani, Tokiko Nakai, Chiho Obayashi, Akira Mitoro, Junichi Yamao, Hitoshi Yoshiji   +18 more
doaj   +1 more source

Organoids From Mucinous Appendiceal Adenocarcinomas as High-Fidelity Models for Individual Therapy

Frontiers in Medicine, 2022
BackgroundMucinous appendiceal adenocarcinoma (MAA) is a rare, heterogeneous disease. Patients with unrespectable mucinous appendiceal adenocarcinoma presenting with peritoneal spread are treated by intraperitoneal chemotherapy, hyperthermic ...
Guangyao Liu, Xing Xiao, Yujian Xia, Weibing Huang, Wei Chen, Jiannan Xu, Songyao Chen, Huijin Wang, Jitao Wei, Huan Li, Man Shu, Xiaofang Lu, Changhua Zhang, Yulong He, Yulong He   +14 more
doaj   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Recidiva pélvica do adenocarcinoma retal. [PDF]

, 1998
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Gomes, André de Miranda
core