Results 71 to 80 of about 43,883 (271)

Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma.: IGF1R inhibition in mucinous lung adenocarcinoma

, 2011
International audienceThe appropriate selection of patients is a major challenge in the treatment of non-small cell lung cancer (NSCLC) with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs).
Tenaud, Corine, de Fraipont, Florence, Martine Antoine, Jacques Cadranel, Cadranel, Jacques, Wislez, Marie, Benoît Busser, Denis Moro-Sibilot, Dufort, Sandrine, Hurbin, Amandine, Moro-Sibilot, Denis, Marie Wislez, Rabbe, Nathalie, Jean-Luc Coll, Sandrine Dufort, Amandine Hurbin, Corine Tenaud, Florence de Fraipont, Busser, Benoît, Nathalie Rabbe, Antoine, Martine, Coll, Jean-Luc, Brambilla, Elisabeth, Elisabeth Brambilla   +23 more
core   +1 more source

Mucinous Carcinoma of the Skin: A Case Report

Journal of Nepal Medical Association, 2022
Primary mucinous carcinoma of the skin is a rare malignant neoplasm showing predilection to the periorbital region. These tumours are indolent and low-grade, with a tendency for local, sometimes multiple, recurrences.
Adarsh Kumar Jhunjhunwala, Dilasma Gharti Magar, Dipesh Upreti, Niku Thapa, Arnab Ghosh, Sushma Thapa, Sudeep Regmi, Bishowdeep Timilsina   +7 more
doaj   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Significance of signet ring cells in high-grade mucinous adenocarcinoma of the peritoneum from appendiceal origin.

, 2014
Significance of signet ring cells in mucinous adenocarcinoma of the peritoneum from appendiceal origin has never been specifically studied. We retrospectively reviewed cases of mucinous adenocarcinoma of the peritoneum from appendiceal origin (n = 55 ...
Blackham, Aaron U, MD, Stewart, John H, Levine, Edward A, Shen, Perry, Bergman, Simon, Votanopoulos, Konstantinos, Geisinger, Kim R, Sirintrapun, S Joseph, Russell, Greg   +8 more
core   +2 more sources

Stromal Regulation of Tumor Perineural Invasion: A Multicellular and Neuro‐Ecological Perspective

Advanced Science, EarlyView.
This review reframes perineural invasion (PNI) as a dynamic, multicellular process within the tumor–nerve–stromal ecosystem. The authors delineate how cancer‐associated fibroblasts, Schwann cells, and immune cells remodel the neural niche to facilitate tumor spread.
Xiaoyang Lin, Yingqiao Liu, Haitao Lin, Kang Feng, Xiqiang Liu   +4 more
wiley   +1 more source

Mucinous adenocarcinoma of prostate and prostatic adenocarcinoma with mucinous components: a clinicopathological analysis of 143 cases

, 2017
Aim: The clinical significance of mucinous prostatic adenocarcinoma (PCa) remains ...
Samaratunga, Hemamali, Srigley, John R., Delahunt, Brett, Yaxley, John, Nacey, John N., Coughlin, Geoffrey, Egevad, Lars, Gianduzzo, Troy, Kua, Boon, Patterson, Imogen, Johannsen, Shulammite   +10 more
core   +1 more source

Prevalence of MSI‐H/dMMR Colorectal Cancer in Japan: Data From the Clinical Study Group of the University of Osaka‐Colorectal Registry

Annals of Gastroenterological Surgery, EarlyView.
Using a multicenter Japanese colorectal cancer cohort from 25 institutions, we analyzed 1464 patients across all disease stages and tumor locations to determine the prevalence and clinicopathological features of MSI‐H/dMMR colorectal cancer. MSI‐H/dMMR tumors accounted for 9.4% of cases overall, were present in 22% of right‐sided colon cancers, and ...
Yoshihiro Morimoto, Mamoru Uemura, Yoshinori Kagawa, Hidekazu Takahashi, Masayuki Hiraki, Yozo Suzuki, Shinichi Yoshioka, Mitsuyoshi Tei, Shu Okamura, Yukako Mokutani, Atsushi Naito, Shinji Tokuyama, Takamichi Komori, Akinobu Yasuyama, Genta Sawada, Yujiro Fujie, Shinya Yamashita, Naotsugu Haraguchi, Yusuke Matsuura, Chu Matsuda, Yoshinao Chinen, Tatsushi Shingai, Katsuki Danno, Nobuo Tanaka, Kazuya Sakata, Kohei Murata, Yuichiro Doki, Hidetoshi Eguchi   +27 more
wiley   +1 more source

Mucinous adenocarcinoma arising in an anorectal fistula

, 2008
Mucinous adenocarcinoma in association with chronic anal fistula is a rare case in clinical practice. The aim of this article was to report a rare case of anal gland mucinous adenocarcinoma in a patient who was treated in the Hospital of Kaunas ...
Linas Venclauskas, Dainius Pavalkis, Darius Pranys, Žilvinas Saladžinskas, Algimantas Tamelis   +4 more
core   +1 more source

Pancreatic Atrophy: A Narrative Review and Surgical Interpretation

Annals of Gastroenterological Surgery, EarlyView.
Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino, Ken‐ichi Okada, Yohei Masugi, Eisuke Iwasaki, Masaki Mori   +4 more
wiley   +1 more source

Biology of invasive mucinous adenocarcinoma of the lung. [PDF]

, 2017
Invasive mucinous adenocarcinoma (IMA) is a unique histologic subtype of lung adenocarcinoma. Recent studies document distinctive genetic alterations (e.g., NRG1 fusions) and a "mucinous gene signature" in IMAs, as well as differences in clinical ...
심효섭, 차윤진
core   +1 more source