Results 101 to 110 of about 1,201,752 (348)

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

Cancer Cell, 2012
SUMMARY Pancreatic ductal adenocarcinomas (PDA) are characterized by a robust fibroinflammatory response. We show here that this desmoplastic reaction generates inordinately high interstitial fluid pressures (IFP), exceeding those previously measured or ...
Paolo P. Provenzano, C. Cuevas, Amy E Chang, V. Goel, D. V. Von Hoff, S. Hingorani   +5 more
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Solitary Metastasis of Pulmonary Adenocarcinoma in Restricted Thyroid Gland Nodule

Bezmiâlem Science, 2018
Metastatic tumors of thyroid are rare and constitute 1.2% of all thyroid malignancies. Metastasis to thyroid gland from head and neck region occurs usually via direct spread.
Esra PAŞAOĞLU, Feray GÜNVER, Zuhal GÜCİN   +2 more
doaj   +1 more source

Impact of changing US cigarette smoking patterns on incident cancer: Risks of 20 smoking-related cancers among the women and men of the NIH-AARP cohort [PDF]

, 2015
Background: Historically, US women started smoking at a later age than men and had lower relative risks for smoking-related cancers. However, more recent birth cohorts of women and men have similar smoking histories and have now reached the high-risk age
Abnet, Christian C, Caporaso, Neil E, Fraumeni, Joseph F, Jr., Freedman, Neal D, Hartge, Patricia, Hollenbeck, Albert R, Murphy, Gwen, Park, Yikyung, Shiels, Meredith S, Silverman, Debra T   +9 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Tumor de colon. Reporte de dos casos y revisión de la literatura

Medisur, 2013
El cáncer de colon es actualmente un importante problema de salud pública en los países desarrollados. Es el cuarto cáncer más frecuente en el mundo, y también en Cuba.
Yarisdey Corrales Hernández
doaj  

Digital morphometry of cytologic aspirate endometrial samples [Digitalna morfometrijska analiza citoloških uzoraka aspirata endometrija] [PDF]

, 2010
Unlike cervical cytology, morphological cytology criteria in the differential diagnosis of endometrium have not yet been clearly defined, and methods to allow for more precise evaluation of endometrium status have been searched for.
Babić, Damir, Barišić, Ana, Božikov, Jadranka, Ilić-Forko, Jadranka, Jurič, Danijela, Mahovlić, Vesna, Ovanin-Rakić, Ana, Rajhvajn, Sanda, Šamija Projić, Ivana, Škopljanac-Mačina, Lada, Škrablin-Kučić, Snježana   +10 more
core  

Uterine adenocarcinoma with abdominal metastases in an ovariohysterectomised female cat [PDF]

, 2011
An adenocarcinoma of the uterine stump with abdominal metastases is described in a 12-year-old incompletely ovariohysterectomised female Domestic Short Haired (DSH) cat.
Belter LF, Meier H, O'Rourke MD, Preiser H, Schmidt RE   +4 more
core   +1 more source

Pancreatic Ductal Adenocarcinoma: Current and Evolving Therapies

International Journal of Molecular Sciences, 2017
Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is the fourth leading cause of cancer-related deaths in the world.
A. Adamska, A. Domenichini, M. Falasca
semanticscholar   +1 more source

Adenocarcinoma of jejunum [PDF]

Journal of Surgical Case Reports, 2018
Although gastrointestinal malignancy is still the major concern of health problems in Worldwide and Thailand, but small intestinal malignancy is extremely rare. The location of small intestinal malignancy is duodenum (73.6%), jejunum (13.2%) and ileum (13.2%).
openaire   +2 more sources