Results 111 to 120 of about 987,160 (289)

Correlation of prostate-specific antigen levels with Gleason score and tumor percentage on prostate needle biopsy in prostate cancer

open access: yesJournal of Dr. NTR University of Health Sciences
Introduction: Prostate-specific antigen (PSA) plays an important role in the detection of prostate cancer. Although it has high sensitivity and low specificity, it is still used clinically. A biopsy is recommended if any abnormality is detected in PSA or
Priyanka Singh   +3 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

A Rare Case with Recurrent Abdominal Pain as the First Symptom: AL Amyloidosis with Colon Involvement Combined with Pulmonary Adenocarcinoma

open access: yesJournal of Inflammation Research
Jiaojiao Wei, Yibing Hu, Chong Lu, Minli Hu, Qunying Wang Department of Gastroenterology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang, People’s Republic of ChinaCorrespondence: Qunying Wang, Department of ...
Wei J, Hu Y, Lu C, Hu M, Wang Q
doaj  

Adenocarcinoma of the lung mimicking interstitial lung disease

open access: yesGülhane Tıp Dergisi
Atypical radiologic and clinical patterns may be observed within subgroups of lung adenocarcinoma. A 74-year-old man with progressive dyspnea and productive cough unresponsive to antibiotherapy showed bilateral interstitial changes in the lung parenchyma
Sümeyye Kodalak Cengiz   +3 more
doaj   +1 more source

139MO Tislelizumab (TIS) plus chemotherapy (Chemo) vs placebo (PBO) plus chemo as first-line (1L) treatment of advanced gastric or gastroesophageal junction adenocarcinoma (GC/GEJC): Final analysis results of the RATIONALE-305 study [PDF]

open access: bronze, 2023
R-H. Xu   +18 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Adenocarcinoma de intestino delgado. Presentación de un caso

open access: yesRevista Finlay, 2012
Las neoplasias malignas de intestino delgado son raras y merece comunicar su forma de presentación. En este artículo se presenta el caso de una paciente de 55 años, con antecedentes de anemia de difícil tratamiento desde hacía algunos meses y que ingresó
Miguel Ángel Serra Valdés   +2 more
doaj  

Yolk Sac Tumor in Ascitic Fluid – Cytodiagnosis of a Rare Case

open access: yesArchives of Medicine and Health Sciences
Yolk sac tumor (YST) is a germ cell tumor of gonads presenting in children and young adults. It is rare to find metastasis of the YST in effusion fluid.
Meesa Mehraj   +4 more
doaj   +1 more source

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