Results 171 to 180 of about 672,479 (309)

Assessment of atypical glandular cell interpretation in Pap tests using the Hologic Genius Digital Diagnostics System. [PDF]

Cancer Cytopathol
Jones TE, Matsko J, Wu D, Zeng X, Colaizzi A, Brown H, Pantanowitz L, Zhao C.   +7 more
europepmc   +1 more source

A Pancreatitis‐Inspired Trypsinogen Nanoplatform Reprograms Tumor‐Associated Macrophages via NF‐κB for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
Trypsinogen‐loaded nanoparticles reprogram TAMs via NF‐κB/NLRP3, driving M2→M1 conversion and potent phagocytosis to unleash antitumor immunity. ABSTRACT Although reprogramming tumor‐associated macrophages (TAMs) represents a promising therapeutic strategy, approaches that are both precise and safe remain scarce.
Lei Cao, Yu He, Wenhao Li, Bo Gong, Han Lin, Jianlin Shi, Yuan Yong, Wencheng Wu   +7 more
wiley   +1 more source

Evaluation of isthmin-1 immunoreactivity in gastric adenocarcinoma. [PDF]

Arq Bras Cir Dig
Ağ O, Yur M, Hançer S, Bozan MB, Özercan IH, Kuloglu T.   +5 more
europepmc   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Immunohistochemical Study of p53 and Ki-67 in Benign and Malignant Prostatic Lesions. [PDF]

Cureus
Shrivastava A, Patil V, Patil S.
europepmc   +1 more source

PFKFB4 Deubiquitination by USP10 Enhances Fumarate Metabolism to Orchestrate the KDM1A/Rad51 Axis and Confer Radioresistance in Lung Cancer

Advanced Science, EarlyView.
USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen, Zilong Wu, Yongqiang Yang, Ruoxin Fang, Huichan Xue, Rui Zhou, Gang Wu, Xiaohua Jie   +7 more
wiley   +1 more source

Acute Small Bowel Obstruction as the First Manifestation of Occult Lung Adenocarcinoma: A Case Report of Jejunal Metastasis. [PDF]

Am J Case Rep
Touati M, Korbi I, Hassine HB, Boughanmi F, Njima M, Gaied Chortane S, Noomen F.   +6 more
europepmc   +1 more source

BRONCHOGENIC ADENOCARCINOMA

Journal of Thoracic Surgery, 1951
M M, PATTON, J R, McDONALD, H J, MOERSCH
openaire   +2 more sources

Modulation of Lung Adenocarcinoma by Phosphorylated FOXN3‐Mediated Transcriptional Inactivation of p53

Advanced Science, EarlyView.
In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu, Jingyu Yu, Suhui Wang, Xinghong Hu, Lele Jin, Nan Wu, Yuhan Ni, Xueying Zhang, Chengling Zhao, Jihong Zhou, Yong Zhang, Baofa Sun, Hongxing Zhang, Chunfu Zheng, Song Guo Zheng, Wei Li, Xinxing Zhu   +16 more
wiley   +1 more source

Synchronous medullary carcinoma of the pancreas and non-ampullary duodenal adenocarcinoma. [PDF]

Arch Clin Cases
D'Avila L, Tee JY, Sharma A, Alabraba E, Zaitoun AM.   +4 more
europepmc   +1 more source