Results 181 to 190 of about 987,160 (289)

The potential role of extracellular regulatory kinase in the survival of patients with early stage adenocarcinoma.

, 2014
Simone de Leon Martini, Carolina Müller, Rosalva Thereza Meurer, Marilda da Cruz Fernandes, Rodrigo Mariano, Mariel Barbachan e Silva, Fábio Klamt, Cristiano Feijó Andrade   +7 more
openalex   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Occult collision tumor of the gastroesophageal junction comprising adenocarcinomas with distinct molecular profiles

Maryjka B. Blaszczyk, Sarag Boukhar, Zhongren Zhou, Lyudmyla Berim, Shridar Ganesan, Gregory Riedlinger   +5 more
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Molecular characterization of early-stage multi-primary lung adenocarcinoma by transcriptome sequencing-a retrospective study. [PDF]

PeerJ
Zhang F, Zhao G.
europepmc   +1 more source

Tubulostromal Adenocarcinoma [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Positive Feedback Loop of Histone Lactylation‐Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance

Advanced Science, EarlyView.
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang, Jiao Chen, En‐Liang Zhu, Ming‐Jian Ma, Yang‐Yin‐Hui Yu, Ying‐Qin Zhu, Jing‐Yuan Ye, Jin‐Zhao Xie, Zi‐Yi Zhao, Xiao‐Yu Yin   +9 more
wiley   +1 more source

Mucinous adenocarcinoma transformed from tailgut cyst: a case report and review of the literature. [PDF]

Front Oncol
Guo Q, Parker JB, Henderson A, Khoor A, Mohseni MM.   +4 more
europepmc   +1 more source

[Splenic metastasis from colonic adenocarcinoma - about a case and literature review].

, 2011
Fatima Zahra Mrabet, Sami Aziz Brahmi, Siham Alaoui Rachidi, S. Tizniti, Afaf Amaarti, Khalid Ait Taleb, Omar El Mesbahi   +6 more
openalex   +2 more sources