Results 281 to 290 of about 1,279,856 (386)

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia associated with lung adenocarcinoma: clinical, pathological and oncological outcomes from a multicentre analysis. [PDF]

ERJ Open Res
Congedo MT, Nachira D, Cancellieri A, Napolitano AG, Meacci E, Fournel L, Mastromarino MG, Sassorossi C, Calandriello L, Chiappetta M, Macagno F, Santoro G, Rindi G, Lucchi M, Vita ML, Petracca-Ciavarella L, Margaritora S, Lococo F.   +17 more
europepmc   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Sequential Gastric MALT Lymphoma and Early Signet Ring Cell Adenocarcinoma in a Patient With Chronic Hepatitis B and Prior <i>Helicobacter pylori</i> Infection. [PDF]

ACG Case Rep J
Pinkert V, Mitra A, Javia S.
europepmc   +1 more source

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.

Cancer Cell, 2012
Paolo P. Provenzano, C. Cuevas, Amy E Chang, V. Goel, D. V. Von Hoff, S. Hingorani   +5 more
semanticscholar   +1 more source

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

Advanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang, Huanhuan Huang, Kaizong Huang, Xiaowen Cui, Leilei Wu, Renyu Lin, Zhe Zhao, Hua Chen, Cheng Zheng, Weilin Jin, Song Chen, Jiayan Chen, Yaping Xu, Dongping Wei   +13 more
wiley   +1 more source

Two Cases of Epidermal Growth Factor Receptor L861R Mutation-Positive Lung Adenocarcinoma Treated With Osimertinib and Afatinib. [PDF]

Cancer Rep (Hoboken)
Kagawa K, Masuda T, Shimoji K, Yamaguchi K, Sakamoto S, Horimasu Y, Nakashima T, Iwamoto H, Hamada H, Hattori N.   +9 more
europepmc   +1 more source

Micropallet arrays for the capture, isolation and culture of circulating tumor cells from whole blood of mice engrafted with primary human pancreatic adenocarcinoma

, 2013
Philip C. Gach, Peter J. Attayek, Rebecca L. Whittlesey, Jen Jen Yeh, Nancy L. Allbritton   +4 more
openalex   +1 more source

Hinokitiol induces cell death and inhibits epidermal growth factor-induced cell migration and signaling pathways in human cervical adenocarcinoma

, 2020
Chih-Chun Wang, Ben-Kuen Chen, Peng-Hsu Chen, Lei-Chin Chen   +3 more
openalex   +1 more source

The Circular RNA circPRKCI Promotes Tumor Growth in Lung Adenocarcinoma.

Cancer Research, 2018
M. Qiu, W. Xia, Rui-Pei Chen, Siwei Wang, Youtao Xu, Zhifei Ma, Weizhang Xu, E. Zhang, Jie Wang, T. Fang, Jing-wen Hu, Gaochao Dong, R. Yin, Jun Wang, Lin Xu   +14 more
semanticscholar   +1 more source

Targeting Mast Cell Activation and MIF‐Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer

Advanced Science, EarlyView.
Neoadjuvant gemcitabine plus nab‐paclitaxel (AG) reprograms pancreatic ductal adenocarcinoma by shifting malignant cells toward a classical phenotype and remodeling the tumor microenvironment. Despite enhancing cytotoxic NKT cells, AG activates tumor‐associated mast cells (TAMCs) and inflammatory CAFs through MIF signaling.
Libo Wang, Guangcong Shen, Guanpeng Xie, Zekun Li, Xiaoqing Ma, Mengyu Li, Ziyun Liu, Yadi Wang, Zongjing Lv, Qingxiao Fang, Huihui Sun, Ningning Zhao, Chao Yang, Tianxing Zhou, Yongjie Xie, Jun Yu, Jihui Hao   +16 more
wiley   +1 more source