Results 41 to 50 of about 7,279 (128)

Expression analysis of the TGF-β/SMAD target genes in adenocarcinoma of esophagogastric junction

Open Medicine, 2016
The TGF-β/SMAD signaling pathway is found to play pivotal roles in cell growth, differentiation and tumorigenesis. Its target genes are closely related to the biological behaviors of some malignancies.
Peng Defeng, Fu Lin, Sun Guoping
doaj   +1 more source

Intestinal Metaplasia of the Distal Esophagus in a Patient With Untreated Achalasia—An Unusual Case and Review of Literature

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Barrett's esophagus (BE) and achalasia are distinct esophageal disorders with opposing pathophysiologic mechanisms, making their coexistence exceedingly rare. We describe a 51‐year‐old woman who presented with progressive dysphagia, postprandial vomiting, and significant weight loss over 8 months.
Rohan Karkra, Mahinaz Mohsen, Salil Chowdhury, Kaveh Hajifathalian, Ahmed Al‐Khazraji   +4 more
wiley   +1 more source

Clinical Characteristics and Novel Manometric Features of Pseudoachalasia: Identification of Loss of Respiratory Variation in Lower Esophageal Sphincter Pressure

JGH Open, Volume 10, Issue 9, September 2026.
ABSTRACT Background Pseudoachalasia closely mimics idiopathic achalasia in both symptoms and high‐resolution manometry (HRM) findings, making accurate diagnosis difficult. This study aimed to clarify the clinical characteristics of pseudoachalasia encountered at our institution and identify novel manometric findings specific to this condition.
Eri Nishikawa, Shinwa Tanaka, Hirofumi Abe, Hiroshi Tanabe, Shinya Hoki, Hitomi Hori, Tatsuya Nakai, Chise Ueda, Satoshi Urakami, Tetsuya Yoshizaki, Takashi Toyonaga, Yuzo Kodama   +11 more
wiley   +1 more source

Patterns of recurrence in adenocarcinoma of the esophagogastric junction: a retrospective study

World Journal of Surgical Oncology, 2020
Background The prognosis of adenocarcinoma of the esophagogastric junction (AEG) is poor. Understanding the postoperative recurrence pattern of AEG is helpful to verify the effectiveness of treatment and optimize subsequent treatment, so as to improve ...
Haitao Xu, Lianguo Zhang, Jing Miao, Shuai Liu, Hongjian Liu, Teng Jia, Qingguang Zhang   +6 more
doaj   +1 more source

Long‐Term Prognosis and Immunotranscriptomic Landscape in Esophageal Squamous Cell Carcinoma With Different Pathological Responses to Neoadjuvant Chemoradiotherapy: A Retrospective Cohort Study

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This study comprehensively characterizes the long‐term prognosis and immunotranscriptomic landscape associated with different tumor regression grades (TRGs) in esophageal squamous cell carcinoma (ESCC) following neoadjuvant chemoradiotherapy. By integrating bulk RNA‐seq, single‐cell transcriptomics, and multiplexed immunohistochemistry, we demonstrate ...
Jianye Yuan, Zelin Weng, Xinke Zhang, Fangqi Deng, Zihui Tan, Jian Zhong, Rui Chen, Xiuying Xie, Xiaodan Lin, Ting Lin, Yan Huang, Qianwen Liu, Jing Wen, Jianhua Fu   +13 more
wiley   +1 more source

Advances in therapeutic approaches to gastric cancer

CA: A Cancer Journal for Clinicians, Volume 76, Issue 5, September/October 2026.
Abstract Gastric cancer remains a leading cause of cancer‐related mortality worldwide, with nearly 1 million new cases diagnosed annually. Despite innovations in diagnosis, most patients still present at advanced stages, contributing to a poor prognosis.
Feng Wang, Zi‐Xian Wang, Yu‐Jing Zhang, Ye He, Jia‐Fu Ji, Yuan‐Fang Li, Xiu‐Juan Qu, Yi Ba, Shu‐Qiang Yuan, Rui‐Hua Xu   +9 more
wiley   +1 more source

Habitat radiomics assists radiologists in accurately diagnosing lymph node metastasis of adenocarcinoma of the esophagogastric junction

Insights into Imaging
Objectives This study aimed to develop a habitat radiomics (HR) model capable of preoperatively predicting lymph node metastasis (LNM) in adenocarcinoma of the esophagogastric junction (AEG) and to implement its use in clinical practice.
Pingfan Jia, Yueying Li, Haonan Li, Yuan Li, Huijuan Qin, Anyu Xie, Yuru Li, Luyao Wang, Luqin Ke, Huijie Feng, Hongwei Yu, Juan Li, Ning Yuan, Xing Guo   +13 more
doaj   +1 more source

Complex diagnosis and management of metastatic esophagogastric junction adenocarcinoma with colonic and meningeal involvement

Einstein (São Paulo)
This report presents a case of a 59-year-old male diagnosed with metastatic esophagogastric junction adenocarcinoma, who presented with mild dysphagia and vertigo. Brain magnetic resonance imaging initially showed no abnormalities. Upper gastrointestinal
Isadora Yasbick Spricido, Tomás Costa Bignoto, Yuri Greb Vazquez, Pedro Henrique Zavarize de Moraes   +3 more
doaj   +1 more source

Endoscopic diagnosis and screening of Barrett's esophagus: Inconsistency of diagnostic criteria between Japan and Western countries

DEN Open, 2022
Barrett's esophagus (BE) is an endoscopically identifiable premalignant condition for esophageal adenocarcinoma (EAC). To diagnose BE precisely, careful inspection of the anatomic landmarks, including the esophagogastric junction and the squamocolumnar ...
Norihisa Ishimura, Eiko Okimoto, Kotaro Shibagaki, Shunji Ishihara   +3 more
doaj   +1 more source

Neuropsychiatric disorder as early clinical presentation of marantic endocarditis in patient with newly diagnosed poorly differentiated esophago‐gastric junction adenocarcinoma: A case report

Clinical Case Reports
Key Clinical Message Neuropsychiatric symptoms, depression, and progressive mental confusion should not be overlooked as onset symptoms of multiple cerebral ischemic lesions due to cardiac embolization.
Filomena Ferrentino, Sara Campana, Marco Torri, Carlo Rostagno   +3 more
doaj   +1 more source