Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface
Advanced Science, EarlyView.This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu +12 more
wiley +1 more source
Loss of heterozygosity in the tuberous sclerosis gene associated regions in adenocarcinoma of the lung accompanied by multiple atypical adenomatous hyperplasia [PDF]
, 1998 Kenji Suzuki +7 more
openalex +1 more source
Correction to: GPC3 affects the prognosis of lung adenocarcinoma and lung squamous cell carcinoma. [PDF]
BMC Pulm Med, 2021 Ning J +8 more
europepmc +1 more source
Advanced Science, EarlyView.This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen +8 more
wiley +1 more source
Adenocarcinoma of the Bovine Lung Derived from Bronchial Ciliated Epithelial Cells
, 1985 NOBUMI SHIMIZU
openalex +2 more sources
Prognostic value of loss of heterozygosity and KRAS2 mutations in lung adenocarcinoma [PDF]
, 1998 Laura De Gregorio +6 more
openalex +1 more source
Autophagy characteristics and establishment of autophagy prognostic models in lung adenocarcinoma and lung squamous cell carcinoma. [PDF]
PLoS One, 2022 Chen Z, Xiong H, Shen H, You Q.
europepmc +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Long-term survival in inoperable adenocarcinoma of the lung.
, 1988 Ryosuke Ono
openalex +2 more sources