Results 281 to 290 of about 3,117,738 (383)

Altered Expression of the ERM Proteins in Lung Adenocarcinoma [PDF]

, 2000
Masahide Tokunou, Toshiro Niki, Y Saitoh, Hiroji Imamura, Michiie Sakamoto, Setsuo Hirohashi   +5 more
openalex   +1 more source

TRIM38 Suppresses the Progression of Colorectal Cancer via Enhancing CCT6A Ubiquitination to Inhibit the MYC Pathway

Advanced Science, Volume 12, Issue 16, April 24, 2025.
This study reveals the tumor‐suppressive role of TRIM38 in colorectal cancer (CRC). TRIM38 is downregulated through DNA hypermethylation and correlates with unfavorable clinical features and poor prognosis. Mechanistically, TRIM38 inhibits CRC progression by promoting K48‐linked ubiquitination of CCT6A, leading to the destabilization of c‐Myc.
Yue Zhang, Xinyu Tan, Lu Wang, Dongjian Ji, Chuan Zhang, Wen Peng, Renzhong Zhu, Xiaowei Wang, Jiahui Zhou, Yifei Feng, Yueming Sun   +10 more
wiley   +1 more source

Mesenchymal-epithelial transition factor exon 14 skipping mutation-positive granulocyte colony-stimulating factor-producing lung adenocarcinoma mimicking lung abscess: A case report. [PDF]

Respirol Case Rep
Izumiya Y, Odaka H, Kikuchi T, Takita Y, Tokairin T.   +4 more
europepmc   +1 more source

Posterior Subglottic Mass in a Patient With a History of Rectal Adenocarcinoma and Lung Metastases. [PDF]

JAMA Oncol, 2020
Craig F, O'Sullivan Coyne G, Allen CT.
europepmc   +1 more source

Transition from Squamous Cell Carcinoma to Adenocarcinoma in Adenosquamous Carcinoma of the Lung [PDF]

, 2000
Hironobu Kanazawa, Masahito Ebina, Nozomu Ino-oka, Minoru Shimizukawa, Toru Takahashi, Shigefumi Fujimura, Tadashi Imai, Toshihiro Nukiwa   +7 more
openalex   +1 more source

Phosphorylation of POU3F3 Mediated Nuclear Translocation Promotes Proliferation in Non‐Small Cell Lung Cancer through Accelerating ATP5PF Transcription and ATP Production

Advanced Science, Volume 12, Issue 13, April 3, 2025.
POU3F3 is significantly upregulated in non‐small cell lung cancer (NSCLC). Activated ERK1 directly interacts with and phosphorylates POU3F3, facilitating its nuclear translocation in NSCLC cells. Within the nucleus, POU3F3 functions as a transcription factor to enhance ATP5PF expression, thereby increasing the activity of mitochondrial complex V and ...
Qi‐Gang Zeng, Le Li, Tao Chang, Yong Sun, Bin Zheng, Ling‐Na Xue, Chao‐Ling Liu, Xia‐Qing Li, Ruo‐Tong Huang, Jia‐Xin Gu, Zhao‐Rong An, Hao‐Tao Yao, Dan‐Yang Zhou, Jun Fan, Yong Dai   +14 more
wiley   +1 more source

Characterization of the tumor immune-microenvironment of adenocarcinoma of lung with a metastatic lesion in the pancreas treated successfully with first-line, single-agent pembrolizumab. [PDF]

Ther Adv Med Oncol, 2021
Saltman DL, Nielsen TJ, Salina D, Hout DR, McMahon FB, Valev BR, Huk M, Chandra PK, Spille J, Seitz RS, Schweitzer BL.   +10 more
europepmc   +1 more source

Synthetic Lethality of SHP2 and XIAP Suppresses Proliferation and Metastasis in KRAS‐mutant Nonsmall Cell Lung Cancer

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu, Yu‐wen Sheng, Zhe Fan, Zhao Wu, Ling‐yu Li, Rui‐ying Xi, Xiao‐ke Shi, Guo‐lin Zhang, Fei Wang   +8 more
wiley   +1 more source

In-depth analysis of immune cell landscapes reveals differences between lung adenocarcinoma and lung squamous cell carcinoma. [PDF]

Front Oncol
Wang X, Zheng K, Hao Z.
europepmc   +1 more source

Comprehensive Profiling of Genomic and Transcriptomic Differences between Risk Groups of Lung Adenocarcinoma and Lung Squamous Cell Carcinoma. [PDF]

J Pers Med, 2021
Zengin T, Önal-Süzek T.
europepmc   +1 more source