Results 291 to 300 of about 547,472 (401)

Identification of an immune-related six-long noncoding RNA signature as a novel prognosis biomarker for adenocarcinoma of lung. [PDF]

Biosci Rep, 2021
Miao H, Chen D, Li R, Hu J, Chen Y, Xu C, Wen Z.   +6 more
europepmc   +1 more source

DCAF12 Ubiquitin Ligase Promotes Lung Cancer Metastasis by Modulating the TRiC/CCT Chaperonin Complex

Advanced Science, EarlyView.
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang, Huanhuan Huang, Kaizong Huang, Xiaowen Cui, Leilei Wu, Renyu Lin, Zhe Zhao, Hua Chen, Cheng Zheng, Weilin Jin, Song Chen, Jiayan Chen, Yaping Xu, Dongping Wei   +13 more
wiley   +1 more source

Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma

Proceedings of the National Academy of Sciences of the United States of America, 2016
D. McFadden, K. Politi, A. Bhutkar, Frances K. Chen, Xiaoling Song, Mono Pirun, P. M. Santiago, Caroline Kim-Kiselak, J. Platt, Emily Lee, E. Hodges, Adam P. Rosebrock, R. Bronson, N. Socci, G. Hannon, T. Jacks, H. Varmus   +16 more
semanticscholar   +1 more source

Integrative Proteomic Characterization of Human Lung Adenocarcinoma

Cell, 2020
Junming Xu, Chunchao Zhang, Xiang Wang, Linhui Zhai, Yiming Ma, Y. Mao, Kun Qian, Changqing Sun, Zhiwei Liu, Shangwen Jiang, Minghui Wang, Lin Feng, Lei Zhao, Ping Liu, Bo Wang, Xin Zhao, Hui Xie, Xiaoyun Yang, Liyuan Zhao, Yafei Chang, Jin-hui Jia, Xijun Wang, Yimin Zhang, Yaru Wang, Yikun Yang, Zhixiang Wu, Longhai Yang, Bin Liu, Teng Zhao, Shengguo Ren, A. Sun, Yang Zhao, W. Ying, Fei Wang, Guangshun Wang, Yi Zhang, Shujun Cheng, J. Qin, X. Qian, Yi Wang, Jing Li, F. He, T. Xiao, Minjia Tan   +43 more
semanticscholar   +1 more source

Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation [PDF]

, 2017
Galemmo, Robert A, Jr, Han, Zhenfu, Janetka, James W, Klampfer, Lidija, Owusu, Benjamin Y, Thomas, Shantasia, Venukadasula, Phanindra   +6 more
core   +2 more sources

Mesenchymal-epithelial transition factor exon 14 skipping mutation-positive granulocyte colony-stimulating factor-producing lung adenocarcinoma mimicking lung abscess: A case report. [PDF]

Respirol Case Rep
Izumiya Y, Odaka H, Kikuchi T, Takita Y, Tokairin T.   +4 more
europepmc   +1 more source

Characterization of the tumor immune-microenvironment of adenocarcinoma of lung with a metastatic lesion in the pancreas treated successfully with first-line, single-agent pembrolizumab. [PDF]

Ther Adv Med Oncol, 2021
Saltman DL, Nielsen TJ, Salina D, Hout DR, McMahon FB, Valev BR, Huk M, Chandra PK, Spille J, Seitz RS, Schweitzer BL.   +10 more
europepmc   +1 more source

Targeting Mast Cell Activation and MIF‐Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer

Advanced Science, EarlyView.
Neoadjuvant gemcitabine plus nab‐paclitaxel (AG) reprograms pancreatic ductal adenocarcinoma by shifting malignant cells toward a classical phenotype and remodeling the tumor microenvironment. Despite enhancing cytotoxic NKT cells, AG activates tumor‐associated mast cells (TAMCs) and inflammatory CAFs through MIF signaling.
Libo Wang, Guangcong Shen, Guanpeng Xie, Zekun Li, Xiaoqing Ma, Mengyu Li, Ziyun Liu, Yadi Wang, Zongjing Lv, Qingxiao Fang, Huihui Sun, Ningning Zhao, Chao Yang, Tianxing Zhou, Yongjie Xie, Jun Yu, Jihui Hao   +16 more
wiley   +1 more source

In-depth analysis of immune cell landscapes reveals differences between lung adenocarcinoma and lung squamous cell carcinoma. [PDF]

Front Oncol
Wang X, Zheng K, Hao Z.
europepmc   +1 more source

Comprehensive Profiling of Genomic and Transcriptomic Differences between Risk Groups of Lung Adenocarcinoma and Lung Squamous Cell Carcinoma. [PDF]

J Pers Med, 2021
Zengin T, Önal-Süzek T.
europepmc   +1 more source