Results 51 to 60 of about 1,237 (168)

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG‐TOP2 Study

Cancer Science, Volume 117, Issue 2, Page 522-535, February 2026.
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Kayoko Tao, Takako Yoshioka, Miho Kato, Kazuyuki Komatsu, Shinichi Tsujimoto, Kenichi Sakamoto, Kazuki Tanimura, Minako Sugiyama, Masahiro Sekiguchi, Yoshiko Nakano, Yoshihiro Otani, Yasushi Yatabe, Akihiko Yoshida, Hajime Okita, Junko Hirato, Kenichi Kohashi, Yukichi Tanaka, Shinji Kohsaka, Takashi Kubo, Kuniko Sunami, Makoto Hirata, Shuichi Tsutsumi, Hiroyuki Aburatani, Katsuyoshi Koh, Masahiro Hirayama, Shuhei Karakawa, Yukayo Terashita, Hiroyuki Fujisaki, Takeshi Yagi, Akihiro Yoneda, Shinji Mochizuki, Hiroyuki Shichino, Tatsuya Suzuki, Tetsuya Takimoto, Koichi Ichimura, Chitose Ogawa, Kimikazu Matsumoto, Hitoshi Ichikawa, Motohiro Kato   +38 more
wiley   +1 more source

Endobiota–Estrobolome Profiles in Reproductive‐Aged Women With Ovarian Endometriosis

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose This case–control study investigated whether ovarian endometriosis is associated with altered estrogen metabolism and gut or urogenital microbiota by analyzing enzyme activity, bacterial composition, and variations of estrogen metabolites in fecal, vaginal, and urinary samples. Methods Thirty‐eight reproductive‐aged women were enrolled,
Chia‐Yu Hu, Angel Hsin‐Yu Pai, Yi‐Wen Wang, Pei‐Chen Lu, Hsien‐Ming Wu, Hong‐Yuan Huang   +5 more
wiley   +1 more source

High‐throughput exosomes analysis for ovarian cancer screening based on a double‐positive surface marker detection biochip

BMEMat, Volume 3, Issue 4, December 2025.
A double‐positive surface marker detection approach was developed to conduct exosome surface protein detection in serum samples. It reaches single‐exosome detection, and over 300 exosome protein parameters are analyzed. The diagnostic accuracy achieved 90% in differentiation of high‐grade serous/serous ovarian carcinoma patients, benign patients, and ...
Jiaoyan Qiu, Yu Wu, Yihe Wang, Chao Wang, Soo‐Yeon Cho, Hui Huang, Yu Zhang, Lin Han   +7 more
wiley   +1 more source

A deceptively benign biliary lesion revealing an ALK‐rearranged intrahepatic cholangiocarcinoma

Histopathology, Volume 89, Issue 1, Page 189-192, July 2026.
Anne‐Cécile Brunac, Marie Danjoux, Hadrien Reboul, Ronan Guillemin, Fabrice Muscari, Janick Selves   +5 more
wiley   +1 more source

Data set for reporting paediatric renal tumours: recommendations from the international collaboration on cancer reporting (ICCR)

Histopathology, Volume 87, Issue 2, Page 183-196, August 2025.
This is the first international data set, to our knowledge, produced by the International Collaboration on Cancer Reporting (ICCR) for the reporting of resection specimens of paediatric renal tumours with the aim of standardising pathology reports, facilitating international data comparisons and improving patient management globally.
E J Perlman, F Webster, K T E Chang, A Coulomb, L Galluzzo, N S Graf, E A Mullen, H Okita, M J O'Sullivan, G R Somers, A Treece, M Cohen, M Reyes‐Múgica   +12 more
wiley   +1 more source

Cellular origins of mucinous ovarian carcinoma

The Journal of Pathology, Volume 266, Issue 1, Page 9-25, May 2025.
Abstract Mucinous ovarian carcinoma (MOC) is a rare histotype of epithelial ovarian cancer. Its origins are obscure: while many mucinous tumours in the ovary are metastases from the gastrointestinal tract, MOC can occur as an ovarian primary; however, the cell of origin is not well established.
Nicola S Meagher, Martin Köbel, Anthony N Karnezis, Aline Talhouk, Michael S Anglesio, Andrew Berchuck, Simon A Gayther, Paul PD Pharoah, Penelope M Webb, Susan J Ramus, Kylie L Gorringe   +10 more
wiley   +1 more source

Radiomics analysis of ultrasound images to discriminate between benign and malignant adnexal masses with solid morphology on ultrasound

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 353-363, March 2025.
ABSTRACT Objective The primary aim was to identify radiomics ultrasound features that can distinguish between benign and malignant adnexal masses with solid ultrasound morphology, and between primary malignant (including borderline and primary invasive) and metastatic solid ovarian masses, and to develop ultrasound‐based machine learning models that ...
F. Moro, M. Vagni, H. E. Tran, F. Bernardini, F. Mascilini, F. Ciccarone, C. Nero, D. Giannarelli, L. Boldrini, A. Fagotti, G. Scambia, L. Valentin, A. C. Testa   +12 more
wiley   +1 more source

Mesonephric‐type adenocarcinomas of the ovary: prevalence, diagnostic reproducibility, outcome, and value of PAX2

The Journal of Pathology: Clinical Research, Volume 10, Issue 4, July 2024.
Abstract Mesonephric‐type (or ‐like) adenocarcinomas (MAs) of the ovary are an uncommon and aggressive histotype. They appear to arise through transdifferentiation from Müllerian lesions creating diagnostic challenges. Thus, we aimed to develop a histologic and immunohistochemical (IHC) approach to optimize the identification of MA over its histologic ...
Martin Köbel, Eun Young Kang, Sandra Lee, Travis Ogilvie, Tatjana Terzic, Linyuan Wang, Nicholas JP Wiebe, Zainab Al‐Shamma, Linda S Cook, Gregg S Nelson, Colin JR Stewart, Andreas von Deimling, Felix KF Kommoss, Cheng‐Han Lee   +13 more
wiley   +1 more source

A case of adenofibroma of the uterus.

The Journal of the Japanese Society of Clinical Cytology, 1996
術前の子宮内膜細胞診で腫瘍細胞が検出された腺線維腫 (adenofibroma) の1例を経験したので報告した. 症例は45歳女性で, 月経過多と下腹部痛を主訴とし, 腹部超音波検査で, 子宮腔内に, 漿液を入れた嚢胞を含む腫瘍が発見された. 経過中, 膣より淡黄色の漿液の流出を認め, その後腫瘍が縮小, 症状が軽減したことから, 腫瘍内嚢胞の穿破が生じたものと考えられた. その後の子宮内膜細胞診で, 一部に線毛を伴う, 異型性に乏しい高円柱上皮細胞のシート状集塊を認めた. 摘出された腫瘍は組織学的に, 子宮内膜および筋層と明瞭に境され, 一層の高円柱上皮細胞で覆われた線維性結合組織の葉状, 乳頭状の増生からなっていた.
TOBIOKA, Hirotoshi, SATOH, Masayuki, MAEJIMA, Sumiko, YOSHIDA, Yoshiko, KIKUKAWA, Yoshiichi, YAMAUCHI, Tomofumi, SANO, Fumio, MORI, Michio   +7 more
openaire   +2 more sources

Infiltrative pattern of invasion is independently associated with shorter survival and desmoplastic stroma markers FAP and THBS2 in mucinous ovarian carcinoma

Histopathology, Volume 84, Issue 7, Page 1095-1110, June 2024.
Aims Mucinous ovarian carcinoma (MOC) is a rare ovarian cancer histotype with generally good prognosis when diagnosed at an early stage. However, MOC with the infiltrative pattern of invasion has a worse prognosis, although to date studies have not been large enough to control for covariables. Data on reproducibility of classifying the invasion pattern
Martin Köbel, Eun‐Young Kang, Sandra Lee, Tatjana Terzic, Antony N Karnezis, Prafull Ghatage, Lawrence Woo, Cheng‐Han Lee, Nicola S Meagher, Susan J Ramus, Kylie L Gorringe   +10 more
wiley   +1 more source