Results 1 to 10 of about 71,503 (290)

Upregulation of transferrin receptor-1 induces cholangiocarcinoma progression via induction of labile iron pool

open access: yesTumor Biology, 2017
Labile iron pool is a cellular source of ions available for Fenton reactions resulting in oxidative stress. Living organisms avoid an excess of free irons by a tight control of iron homeostasis.
Wassana Jamnongkan   +7 more
doaj   +1 more source

Intrahepatic Cholangiocarcinoma

open access: yesSeminars in Interventional Radiology, 2020
AbstractCholangiocarcinoma is the second most common primary malignancy of the liver. This review will focus on the mass-forming intrahepatic type of this disease and discuss the role of medical, surgical, and radiation oncology in managing this difficult disease.
Pouya, Entezari, Ahsun, Riaz
openaire   +3 more sources

Intrahepatic Cholangiocarcinoma [PDF]

open access: yesSurgical Oncology Clinics of North America, 2014
Intrahepatic cholangiocarcinoma (ICC) is a rare tumor, with an increasing incidence worldwide and an overall poor prognosis. Symptoms are usually nonspecific, contributing to an advanced tumor stage at diagnosis. The staging system for ICC has recently been updated and is based on number of lesions, vascular invasion, and lymph node involvement ...
Kimberly M, Brown   +2 more
openaire   +2 more sources

Unveiling the Anticancer Potential and Molecular Mechanisms of Fangchinoline Against Cholangiocarcinoma Using FTIR Microspectroscopy, In Vitro and In Silico Approaches

open access: yesIntegrative Cancer Therapies
Objectives: The limited effectiveness of traditional chemotherapeutic agents against cholangiocarcinoma (CCA) highlights the need for novel compounds.
Piman Pocasap   +5 more
doaj   +1 more source

Preoperative Prognostic Score for Patients with Intrahepatic Cholangiocarcinoma Undergoing Curative-Intent Resection

open access: yesMedical Sciences
Background: Preoperative inflammatory and nutrition-related markers—including the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), prognostic nutritional index (PNI), and controlling nutritional status (CONUT) score—have shown ...
Jarin Chindaprasirt   +11 more
doaj   +1 more source

Clinical pharmacokinetics of quinine and its relationship with treatment outcomes in children, pregnant women, and elderly patients, with uncomplicated and complicated malaria: a systematic review

open access: yesMalaria Journal, 2022
Background Standard dosage regimens of quinine formulated for adult patients with uncomplicated and complicated malaria have been applied for clinical uses in children, pregnant women, and elderly.
Teerachat Saeheng, Kesara Na-Bangchang
doaj   +1 more source

FOXM1c is the predominant FOXM1 isoform expressed in cholangiocarcinoma that associated with metastatic potential and poor prognosis of patients

open access: yesHeliyon, 2021
Forkhead box M1 (FOXM1) is a transcriptional factor which plays an important role in oncogenesis. Four FOXM1 isoforms, FOXM1a, FOXM1b, FOXM1c and FOXM1d, are known so far. Different FOXM1 isoforms influence progression of cancer in different cancer types.
Nathakan Klinhom-on   +6 more
doaj   +1 more source

Identifying a unique chromosomal pattern to predict the gemcitabine response in patients with cholangiocarcinoma

open access: yesScientific Reports
Cholangiocarcinoma (CCA) is an epithelial bile duct cancer frequently found at an advanced stage, leading to poor response to current therapies. Although gemcitabine (GEM) and cisplatin (CIS) are the current gold-standard for treating unresectable CCA ...
Sutheemon Techa-ay   +13 more
doaj   +1 more source

Performance of Mini Parasep® SF stool concentrator kit, Kato-Katz, and formalin-ethyl acetate concentration methods for diagnosis of opisthorchiasis in Northeast Thailand

open access: yesParasites & Vectors, 2022
Background Control and elimination of the liver fluke (Opisthorchis viverrini) is a primary preventive strategy against cholangiocarcinoma in Southeast Asia.
Kulthida Y. Kopolrat   +14 more
doaj   +1 more source

Imaging of Cholangiocarcinoma [PDF]

open access: yesVisceral Medicine, 2016
Cholangiocarcinoma (CC) is the second most common primary hepatobiliary tumour, and it is increasing in incidence. Imaging characteristics, behaviour, and therapeutic strategies in CC differ significantly, depending on the morphology and location of the tumour.
Susann-Cathrin, Olthof   +5 more
openaire   +2 more sources

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