Results 1 to 10 of about 71,118 (301)

Cholangiocarcinoma [PDF]

Lancet, The, 2014
SummaryCholangiocarcinoma represents a diverse group of epithelial cancers united by late diagnosis and poor outcomes. Specific diagnostic and therapeutic approaches are undertaken for cholangiocarcinomas of different anatomical locations (intrahepatic ...
Nataliya Razumilava, Gregory J Gores
exaly   +4 more sources

Cholangiocarcinoma in Italy: A national survey on clinical characteristics, diagnostic modalities and treatment. Results from the “Cholangiocarcinoma” committee of the Italian Association for the Study of Liver disease

Digestive and Liver Disease, 2011
Background: Very few studies assessed cholangiocarcinoma clinical characteristics. Aim: To evaluate the clinical characteristics of intra-hepatic (IH) and extra-hepatic (EH)-CCA. Methods: We performed a national survey based on a questionnaire.
Domenico Alvaro, Antonio Benedetti, Luca Fabris   +2 more
exaly   +3 more sources

Chemotherapeutic resistant cholangiocarcinoma displayed distinct intratumoral microbial composition and metabolic profiles [PDF]

PeerJ, 2022
Background Cholangiocarcinoma (CCA) is a malignancy of the cholangiocytes. One of the major issues regarding treatment for CCA patients is the development of chemotherapeutic resistance.
Sirinya Sitthirak, Manida Suksawat, Jutarop Phetcharaburanin, Arporn Wangwiwatsin, Poramate Klanrit, Nisana Namwat, Narong Khuntikeo, Attapol Titapun, Apiwat Jarearnrat, Sakkarn Sangkhamanon, Watcharin Loilome   +10 more
doaj   +2 more sources

Metabolomic analyses uncover an inhibitory effect of niclosamide on mitochondrial membrane potential in cholangiocarcinoma cells [PDF]

PeerJ, 2023
Background Niclosamide is an oral anthelminthic drug that has been used for treating tapeworm infections. Its mechanism involves the disturbance of mitochondrial membrane potential that in turn inhibits oxidative phosphorylation leading to ATP depletion.
Thanaporn Kulthawatsiri, Yingpinyapat Kittirat, Jutarop Phetcharaburanin, Jittima Tomacha, Bundit Promraksa, Arporn Wangwiwatsin, Poramate Klanrit, Attapol Titapun, Watcharin Loilome, Nisana Namwat   +9 more
doaj   +2 more sources

1H NMR fecal metabolic phenotyping of periductal fibrosis- and cholangiocarcinoma-specific metabotypes defining perturbation in gut microbial-host co-metabolism [PDF]

PeerJ, 2023
Background The liver fluke Opisthorchis viverrini (OV), which subsequently inhabits the biliary system and results in periductal fibrosis (PDF), is one of the primarily causes of cholangiocarcinoma (CCA), a bile duct cancer with an exceptionally high ...
Rujikorn Treeriya, Phuc N. Ho, Attapol Titapun, Poramate Klanrit, Manida Suksawat, Thanaporn Kulthawatsiri, Suphasarang Sirirattanakul, Watcharin Loilome, Nisana Namwat, Arporn Wangwiwatsin, Nittaya Chamadol, Narong Khuntikeo, Jutarop Phetcharaburanin   +12 more
doaj   +2 more sources

Accuracy of a new rapid diagnostic test for urinary antigen detection and assessment of drug treatment in opisthorchiasis

Infectious Diseases of Poverty, 2023
Background Screening for opisthorchiasis, a parasitic worm infection affecting many millions of people in Southeast Asia, has traditionally relied on faecal egg examination such as the formalin-ethyl acetate concentration technique (FECT) and Kato-Katz ...
Chanika Worasith, Jiraporn Sithithaworn, Phattharaphon Wongphutorn, Chutima Homwong, Kanoknan Khongsukwiwat, Anchalee Techasen, Kulthida Y. Kopolrat, Watcharin Loilome, Nisana Namwat, Bandit Thinkamrop, Chaiwat Tawarungruang, Attapol Titapun, Thewarach Laha, Ross H. Andrews, Simon D. Taylor-Robinson, Paiboon Sithithaworn   +15 more
doaj   +1 more source

Prognostic Significance of Growth Pattern in Predicting Outcome of Opisthorchis viverrini-Associated Distal Cholangiocarcinoma in Thailand

Frontiers in Public Health, 2022
Distal cholangiocarcinoma (dCCA) is a rare type of CCA in Asia, even in Opisthorchis viverrini-prevalent Northeastern Thailand. The clinical ambiguity and imprecision of diagnosis surrounding this malignancy result in high mortality due often to advanced/
Waritta Kunprom, Waritta Kunprom, Waritta Kunprom, Chaiwat Aphivatanasiri, Chaiwat Aphivatanasiri, Chaiwat Aphivatanasiri, Prakasit Sa-ngiamwibool, Prakasit Sa-ngiamwibool, Prakasit Sa-ngiamwibool, Sakkarn Sangkhamanon, Sakkarn Sangkhamanon, Sakkarn Sangkhamanon, Piyapharom Intarawichian, Piyapharom Intarawichian, Piyapharom Intarawichian, Walailak Bamrungkit, Walailak Bamrungkit, Walailak Bamrungkit, Malinee Thanee, Malinee Thanee, Malinee Thanee, Piya Prajumwongs, Piya Prajumwongs, Piya Prajumwongs, Watcharin Loilome, Watcharin Loilome, Watcharin Loilome, Narong Khuntikeo, Narong Khuntikeo, Narong Khuntikeo, Attapol Titapun, Attapol Titapun, Attapol Titapun, Apiwat Jareanrat, Apiwat Jareanrat, Apiwat Jareanrat, Vasin Thanasukarn, Vasin Thanasukarn, Vasin Thanasukarn, Tharatip Srisuk, Tharatip Srisuk, Tharatip Srisuk, Vor Luvira, Vor Luvira, Vor Luvira, Kulyada Eurboonyanun, Kulyada Eurboonyanun, Kulyada Eurboonyanun, Julaluck Promsorn, Julaluck Promsorn, Julaluck Promsorn, Supinda Koonmee, Supinda Koonmee, Supinda Koonmee   +53 more
doaj   +1 more source

Sulfasalazine modifies metabolic profiles and enhances cisplatin chemosensitivity on cholangiocarcinoma cells in in vitro and in vivo models

Cancer & Metabolism, 2021
Background Sulfasalazine (SSZ) is widely known as an xCT inhibitor suppressing CD44v9-expressed cancer stem-like cells (CSCs) being related to redox regulation. Cholangiocarcinoma (CCA) has a high recurrence rate and no effective chemotherapy.
Malinee Thanee, Sureerat Padthaisong, Manida Suksawat, Hasaya Dokduang, Jutarop Phetcharaburanin, Poramate Klanrit, Attapol Titapun, Nisana Namwat, Arporn Wangwiwatsin, Prakasit Sa-ngiamwibool, Narong Khuntikeo, Hideyuki Saya, Watcharin Loilome   +12 more
doaj   +1 more source

Modification of the eighth AJCC/UICC staging system for perihilar cholangiocarcinoma: An alternative pathological staging system from cholangiocarcinoma-prevalent Northeast Thailand

Frontiers in Medicine, 2022
AimThis study aims to improve the classification performance of the eighth American Joint Committee on Cancer (AJCC) staging system for perihilar cholangiocarcinoma (pCCA) by proposing the Khon Kaen University (KKU) staging system developed in ...
Chaiwat Aphivatanasiri, Chaiwat Aphivatanasiri, Chaiwat Aphivatanasiri, Prakasit Sa-Ngiamwibool, Prakasit Sa-Ngiamwibool, Prakasit Sa-Ngiamwibool, Sakkarn Sangkhamanon, Sakkarn Sangkhamanon, Sakkarn Sangkhamanon, Piyapharom Intarawichian, Piyapharom Intarawichian, Piyapharom Intarawichian, Waritta Kunprom, Waritta Kunprom, Waritta Kunprom, Malinee Thanee, Malinee Thanee, Malinee Thanee, Piya Prajumwongs, Piya Prajumwongs, Piya Prajumwongs, Narong Khuntikeo, Narong Khuntikeo, Narong Khuntikeo, Attapol Titapun, Attapol Titapun, Attapol Titapun, Apiwat Jareanrat, Apiwat Jareanrat, Apiwat Jareanrat, Vasin Thanasukarn, Vasin Thanasukarn, Vasin Thanasukarn, Tharatip Srisuk, Tharatip Srisuk, Tharatip Srisuk, Vor Luvira, Vor Luvira, Vor Luvira, Kulyada Eurboonyanun, Kulyada Eurboonyanun, Kulyada Eurboonyanun, Julaluck Promsorn, Julaluck Promsorn, Julaluck Promsorn, Watcharin Loilome, Watcharin Loilome, Watcharin Loilome, Aileen Wee, Supinda Koonmee, Supinda Koonmee, Supinda Koonmee   +51 more
doaj   +1 more source

Facial Swelling as a Presenting Sign of Cholangiocarcinoma [PDF]

, 2022
Cholangiocarcinoma is a rare primary malignancy of the biliary tree, which usually presents late in the course of disease with jaundice, upper right quadrant pain, and cachexia. They frequently metastasise in the lungs, liver, bones, adrenals, peritoneum,
Nagireddy Bethireddy, Sanjay M. Khaladkar, Darshana Dilip, Purnachandra Lamghare, Vijetha Chanabasanavar   +4 more
core   +1 more source