Results 31 to 40 of about 79,213 (303)

Curcumin-loaded nanocomplexes alleviate the progression of fluke-related cholangiocarcinoma in hamsters

Cancer Nanotechnology, 2023
Background Curcumin-loaded nanocomplexes (CNCs) previously demonstrated lower toxicity and extended release better than is the case for free curcumin. Here, we evaluated the efficacy of CNCs against opisthorchiasis-associated cholangiocarcinoma (CCA) in ...
Chanakan Jantawong, Yaovalux Chamgramol, Kitti Intuyod, Aroonsri Priprem, Chawalit Pairojkul, Sirinapha Klungsaeng, Rungtiwa Dangtakot, Thatsanapong Pongking, Chutima Sitthirach, Porntip Pinlaor, Sakda Waraasawapati, Somchai Pinlaor   +11 more
doaj   +1 more source

Suppression of trophoblast cell surface antigen 2 enhances proliferation and migration in liver fluke-associated cholangiocarcinoma

Annals of Hepatology, 2016
Background and aim. Trophoblast cell surface antigen 2 (TROP2) or tumor-associated calcium signal transducer 2 (TACSTD2) is a 36-kDa type I transmembrane glycoprotein and exerts dual functions as an oncogene and tumor suppressor in cancer cells.
Kanlayanee Sawanyawisuth, Ph.D., Nattawat Tantapotinan, Ratthaphol Kraiklang, Anucha Puapairoj, Chaisiri Wongkham, Gregory J. Riggins, Sopit Wongkham   +6 more
doaj   +1 more source

Survival after surgery among patients with cholangiocarcinoma in Northeast Thailand according to anatomical and morphological classification

BMC Cancer, 2021
Background Cholangiocarcinoma (CCA) has been categorized based on tumor location as intrahepatic (ICCA), perihilar (PCCA) or distal (DCCA), and based on the morphology of the tumor of the bile duct as mass forming (MF), periductal infiltrating (PI) or ...
Chaiwat Tawarungruang, Narong Khuntikeo, Nittaya Chamadol, Vallop Laopaiboon, Jaruwan Thuanman, Kavin Thinkhamrop, Matthew Kelly, Bandit Thinkhamrop   +7 more
doaj   +1 more source

Epigenetic alterations associated with cholangiocarcinoma (Review) [PDF]

, 2009
Cholangiocarcinoma (CCA) is a highly lethal malignant tumor arising from the biliary tract epithelium. Chronic inflammatory conditions, including primary sclerosing cholangitis, liver fluke infestation, and hepatolithiasis, are considered risk factors ...
Isomoto, Hajime
core   +1 more source

RETRACTED ARTICLE: Preclinical studies of toxicity and anti-cholangiocarcinoma activity of the standardized capsule formulation of Atractylodes lancea (Thunb.) DC

BMC Complementary Medicine and Therapies, 2023
Background Cholangiocarcinoma (CCA), the adenocarcinoma of the biliary duct, is commonly reported in Asia, with the highest incidence in northeastern Thailand. Chemotherapy of CCA has been limited by the lack of effective chemotherapeutic drugs. A series
Tullayakorn Plengsuriyakarn, Kanawut Kotawong, Juntra Karbwang, Kesara Na-Bangchang   +3 more
doaj   +1 more source

Immune microenvironment of cholangiocarcinoma: Biological concepts and treatment strategies [PDF]

, 2023
Cholangiocarcinoma is characterized by a poor prognosis with limited treatment and management options. Chemotherapy using gemcitabine with cisplatin is the only available first-line therapy for patients with advanced cholangiocarcinoma, although it ...
Jiang Chen, Xianzhe Yu, Ting Wang, Lingling Zhu   +3 more
core   +1 more source

Associations between ultrasound screening findings and cholangiocarcinoma diagnosis in an at-risk population

Scientific Reports, 2022
The rate of cholangiocarcinoma (CCA) is increasing every year, especially in northeastern Thailand. Screening for CCA using ultrasonography (US) is the fastest technique to identify patients in early stage of CCA development.
Kavin Thinkhamrop, Narong Khuntikeo, Nittaya Chamadol, Apiporn T. Suwannatrai, Surachai Phimha, Matthew Kelly   +5 more
doaj   +1 more source

Diagnosis of Cholangiocarcinoma

Diagnostics, 2023
Cholangiocarcinoma (CCA), a tumor of the bile duct epithelium, is increasing in incidence. CCA remains a highly fatal malignancy because early diagnosis is difficult. Based on its anatomical location, CCA can be categorized into the following three groups: perihilar, intrahepatic, and extrahepatic.
Dong Woo Shin, Sung-Hoon Moon, Jong Hyeok Kim   +2 more
openaire   +3 more sources

Recap on epidemiology of cholangiocarcinoma

, 2021
Cholangiocarcinoma is a type of ...
C. La Vecchia
core  

Cholangiocarcinoma

Surgical Clinics of North America, 1990
The diagnosis of cholangiocarcinoma can now be made with greater rapidity and accuracy. In the clinical setting of obstructive jaundice, a CT scan or sonogram may suggest cholangiocarcinoma if dilated intrahepatic ducts are seen with a nondilated extrahepatic biliary tree.
C J, Yeo, H A, Pitt, J L, Cameron
openaire   +2 more sources