Results 41 to 50 of about 79,213 (303)

Descriptive epidemiology of cholangiocarcinoma in Italy.

, 2009
BACKGROUND: Very little data exist on the epidemiology of cholangiocarcinoma in Italy. AIM: We focus on the descriptive epidemiology of cholangiocarcinoma in Italy.
ALVARO, Domenico, THE AISF CHOLANGIOCARCINOMA COMMITTEE, BRAGAZZI, MARIA CONSIGLIA, CAPOCACCIA R, CROCETTI E, FERRETTI S, Crocetti, Emanuele, Ferretti, Stefano, FABRIS, LUCA, Capocaccia, Riccardo, Domenico Alvaro, Riccardo Capocaccia, Stefano Ferretti, Maria Consiglia Bragazzi, Emanuele Crocetti   +14 more
core   +1 more source

Current Perspectives on Opisthorchiasis Control and Cholangiocarcinoma Detection in Southeast Asia

Frontiers in Medicine, 2018
Similar to bile duct cancer or cholangiocarcinoma (CCA) in the western world, opisthorchiasis-associated CCA in Southeast Asia is an aggressive cancer with high mortality rates.
Narong Khuntikeo, Narong Khuntikeo, Attapol Titapun, Attapol Titapun, Watcharin Loilome, Watcharin Loilome, Puangrat Yongvanit, Puangrat Yongvanit, Bandit Thinkhamrop, Bandit Thinkhamrop, Nittaya Chamadol, Nittaya Chamadol, Thidarat Boonmars, Thidarat Boonmars, Teerachai Nethanomsak, Teerachai Nethanomsak, Ross H. Andrews, Ross H. Andrews, Trevor N. Petney, Trevor N. Petney, Paiboon Sithithaworn, Paiboon Sithithaworn   +21 more
doaj   +1 more source

Identification of serum metabolite biomarkers and metabolic reprogramming mechanisms to predict recurrence in cholangiocarcinoma

Scientific Reports
Cholangiocarcinoma (CCA) has high recurrence rates that severely limit long-term survival. Effective tools for accurate recurrence monitoring and diagnosis remain lacking.
Piya Prajumwongs, Attapol Titapun, Vasin Thanasukarn, Apiwat Jareanrat, Natcha Khuntikeo, Nisana Namwat, Poramate Klanrit, Arporn Wangwiwatsin, Jarin Chindaprasirt, Supinda Koonmee, Prakasit Sa-Ngiamwibool, Nattha Muangritdech, Sittiruk Roytrakul, Watcharin Loilome   +13 more
doaj   +1 more source

Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression

Scientific Reports
Cholangiocarcinoma (CCA) is a prevalent bile duct cancer with limited treatment options. Cisplatin-based chemotherapy is a common approach, but response rates vary.
Sutheemon Techa-ay, Sasithorn Watcharadetwittaya, Raksawan Deenonpoe, Kitti Intuyod, Waleeporn Kaewlert, Anchalee Techasen, Watcharin Loilome, Poramate Klanrit, Manida Suksawat, Kwanjira Chaleekan, Sirinya Sitthirak, Malinee Thanee   +11 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Metabolic and Inflammatory Risk Stratification in Resected Cholangiocarcinoma: A Retrospective Exploratory Analysis

Medical Sciences
Background: Cholangiocarcinoma (CCA) frequently recurs after curative-intent resection. Metabolic alterations and systemic inflammation may contribute to aggressive disease, but their combined prognostic relevance remains unclear.
Piya Prajumwongs, Attapol Titapun, Vasin Thanasukarn, Apiwat Jareanrat, Natcha Khuntikeo, Nisana Namwat, Poramate Klanrit, Arporn Wangwiwatsin, Jarin Chindaprasirt, Prakasit Sa-Ngiamwibool, Nattha Muangritdech, Sittiruk Roytrakul, Watcharin Loilome   +12 more
doaj   +1 more source

Pathology of Cholangiocarcinomas

Current Oncology, 2022
Cholangiocarcinomas (CCA) are heterogeneous tumors that arise from epithelial cells of the biliary tract. They represent the second primary liver malignancy, after hepatocellular carcinoma. Recent epidemiological data show an increased incidence of intrahepatic CCA without any identified causes.
openaire   +3 more sources

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source