Results 21 to 30 of about 96,828 (293)

Preoperative controlling nutritional status (CONUT) score is an independent prognostic factor in cholangiocarcinoma patients treated with hepatectomy

Heliyon, 2023
Background: Nutritional status is one of the important factors determining the short- and long-term outcomes of surgery in cancer. This study aimed to assess the prognostic role of preoperative controlling nutritional status (CONUT) score in intrahepatic
Attapol Titapun, Aumkhae Sookprasert, Yanin Sripanuskul, Piyakarn Watcharenwong, Watcharin Loilome, Prin Twinprai, Tharathip Srisuk, Piya Prajumwongs, Jarin Chindaprasirt   +8 more
doaj   +1 more source

Establishment of a Potential Serum Biomarker Panel for the Diagnosis and Prognosis of Cholangiocarcinoma Using Decision Tree Algorithms

Diagnostics, 2021
Potential biomarkers which include S100 calcium binding protein A9 (S100A9), mucin 5AC (MUC5AC), transforming growth factor β1 (TGF-β1), and angiopoietin-2 have previously been shown to be effective for cholangiocarcinoma (CCA) diagnosis.
Phongsaran Kimawaha, Apinya Jusakul, Prem Junsawang, Raynoo Thanan, Attapol Titapun, Narong Khuntikeo, Anchalee Techasen   +6 more
doaj   +1 more source

Metabolic Phenotyping Predicts Gemcitabine and Cisplatin Chemosensitivity in Patients With Cholangiocarcinoma

Frontiers in Public Health, 2022
Gemcitabine and cisplatin serve as appropriate treatments for patients with cholangiocarcinoma (CCA). Our previous study using histoculture drug response assay (HDRA), demonstrated individual response patterns to gemcitabine and cisplatin.
Manida Suksawat, Manida Suksawat, Manida Suksawat, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Poramate Klanrit, Poramate Klanrit, Poramate Klanrit, Nisana Namwat, Nisana Namwat, Nisana Namwat, Narong Khuntikeo, Narong Khuntikeo, Narong Khuntikeo, Attapon Titapun, Attapon Titapun, Attapon Titapun, Apiwat Jarearnrat, Apiwat Jarearnrat, Apiwat Jarearnrat, Vanlakhone Vilayhong, Vanlakhone Vilayhong, Vanlakhone Vilayhong, Prakasit Sa-ngiamwibool, Prakasit Sa-ngiamwibool, Prakasit Sa-ngiamwibool, Anchalee Techasen, Anchalee Techasen, Anchalee Techasen, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Panupong Mahalapbutr, Panupong Mahalapbutr, Jia V. Li, Watcharin Loilome, Watcharin Loilome, Watcharin Loilome, Watcharin Loilome   +41 more
doaj   +1 more source

Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein

Integrative Cancer Therapies, 2022
Owing to the crucial role of Src in cancer metastasis, interruption of Src and its signaling has been considered a promising strategy for cancer metastasis treatment.
Putthaporn Kaewmeesri MS, Piman Pocasap PhD, Veerapol Kukongviriyapan PhD, Auemduan Prawan PhD, Sarinya Kongpetch PhD, Laddawan Senggunprai PhD   +5 more
doaj   +1 more source

Targeting Fatty Acid Synthase Modulates Metabolic Pathways and Inhibits Cholangiocarcinoma Cell Progression

Frontiers in Pharmacology, 2021
An aberrant regulation of lipid metabolism is involved in the pathogenesis and progression of cancer. Up-regulation of lipid biosynthesis enzymes, including acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and HMG-CoA reductase (HMGCR), has been ...
Jittima Tomacha, Jittima Tomacha, Hasaya Dokduang, Sureerat Padthaisong, Nisana Namwat, Nisana Namwat, Poramate Klanrit, Poramate Klanrit, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Tueanjit Khampitak, Supinda Koonmee, Supinda Koonmee, Attapol Titapun, Attapol Titapun, Apiwat Jarearnrat, Apiwat Jarearnrat, Narong Khuntikeo, Narong Khuntikeo, Watcharin Loilome, Watcharin Loilome   +22 more
doaj   +1 more source

Curcumin-loaded nanocomplexes alleviate the progression of fluke-related cholangiocarcinoma in hamsters

Cancer Nanotechnology, 2023
Background Curcumin-loaded nanocomplexes (CNCs) previously demonstrated lower toxicity and extended release better than is the case for free curcumin. Here, we evaluated the efficacy of CNCs against opisthorchiasis-associated cholangiocarcinoma (CCA) in ...
Chanakan Jantawong, Yaovalux Chamgramol, Kitti Intuyod, Aroonsri Priprem, Chawalit Pairojkul, Sirinapha Klungsaeng, Rungtiwa Dangtakot, Thatsanapong Pongking, Chutima Sitthirach, Porntip Pinlaor, Sakda Waraasawapati, Somchai Pinlaor   +11 more
doaj   +1 more source

Capecitabine as second-line treatment for metastatic cholangiocarcinoma: A report of two cases [PDF]

, 2002
Background: The management of recurrent, metastatic cholangiocarcinoma still remains a problem since this tumor entity is classified as chemotherapy-resistant.
Heinemann, Volker, Schalhorn, A., Stemmler, Joachim   +2 more
core   +1 more source

Survival after surgery among patients with cholangiocarcinoma in Northeast Thailand according to anatomical and morphological classification

BMC Cancer, 2021
Background Cholangiocarcinoma (CCA) has been categorized based on tumor location as intrahepatic (ICCA), perihilar (PCCA) or distal (DCCA), and based on the morphology of the tumor of the bile duct as mass forming (MF), periductal infiltrating (PI) or ...
Chaiwat Tawarungruang, Narong Khuntikeo, Nittaya Chamadol, Vallop Laopaiboon, Jaruwan Thuanman, Kavin Thinkhamrop, Matthew Kelly, Bandit Thinkhamrop   +7 more
doaj   +1 more source

Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]

, 2013
Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico, Carpino, G, Franchitto, Antonio, Gaudio, Eugenio, Mancinelli, Romina, Onori, Paolo, Renzi, Anastasia   +6 more
core   +1 more source

Suppression of trophoblast cell surface antigen 2 enhances proliferation and migration in liver fluke-associated cholangiocarcinoma

Annals of Hepatology, 2016
Background and aim. Trophoblast cell surface antigen 2 (TROP2) or tumor-associated calcium signal transducer 2 (TACSTD2) is a 36-kDa type I transmembrane glycoprotein and exerts dual functions as an oncogene and tumor suppressor in cancer cells.
Kanlayanee Sawanyawisuth, Ph.D., Nattawat Tantapotinan, Ratthaphol Kraiklang, Anucha Puapairoj, Chaisiri Wongkham, Gregory J. Riggins, Sopit Wongkham   +6 more
doaj   +1 more source