Results 21 to 30 of about 79,213 (303)

Establishment of a Potential Serum Biomarker Panel for the Diagnosis and Prognosis of Cholangiocarcinoma Using Decision Tree Algorithms

Diagnostics, 2021
Potential biomarkers which include S100 calcium binding protein A9 (S100A9), mucin 5AC (MUC5AC), transforming growth factor β1 (TGF-β1), and angiopoietin-2 have previously been shown to be effective for cholangiocarcinoma (CCA) diagnosis.
Phongsaran Kimawaha, Apinya Jusakul, Prem Junsawang, Raynoo Thanan, Attapol Titapun, Narong Khuntikeo, Anchalee Techasen   +6 more
doaj   +1 more source

Liver: Intrahepatic cholangiocarcinoma [PDF]

, 2009
Review on Liver: Intrahepatic cholangiocarcinoma, with data on clinics, and the genes ...
Enjoji, M, Aishima, S
core   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Metabolic Phenotyping Predicts Gemcitabine and Cisplatin Chemosensitivity in Patients With Cholangiocarcinoma

Frontiers in Public Health, 2022
Gemcitabine and cisplatin serve as appropriate treatments for patients with cholangiocarcinoma (CCA). Our previous study using histoculture drug response assay (HDRA), demonstrated individual response patterns to gemcitabine and cisplatin.
Manida Suksawat, Manida Suksawat, Manida Suksawat, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Poramate Klanrit, Poramate Klanrit, Poramate Klanrit, Nisana Namwat, Nisana Namwat, Nisana Namwat, Narong Khuntikeo, Narong Khuntikeo, Narong Khuntikeo, Attapon Titapun, Attapon Titapun, Attapon Titapun, Apiwat Jarearnrat, Apiwat Jarearnrat, Apiwat Jarearnrat, Vanlakhone Vilayhong, Vanlakhone Vilayhong, Vanlakhone Vilayhong, Prakasit Sa-ngiamwibool, Prakasit Sa-ngiamwibool, Prakasit Sa-ngiamwibool, Anchalee Techasen, Anchalee Techasen, Anchalee Techasen, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Panupong Mahalapbutr, Panupong Mahalapbutr, Jia V. Li, Watcharin Loilome, Watcharin Loilome, Watcharin Loilome, Watcharin Loilome   +41 more
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

An Autopsy Case of Lepidic Pulmonary Metastasis from Cholangiocarcinoma [PDF]

, 2016
We herein report the first case of pulmonary metastasis with lepidic growth that originated from cholangiocarcinoma. A 77-year-old man was admitted to our hospital due to exertional dyspnea and liver dysfunction.
Nagayoshi, Yohsuke, Doi, Seiji, Kohno, Shigeru, Nakamura, Shigeki, Yamamoto, Kazuko, Hashimoto, Satoru, Ito, Masahiro, Hisatomi, Keiko, Nagashima, Seiji, Miyazaki, Taiga, Kurohama, Hirokazu, Takazono, Takahiro   +11 more
core   +1 more source

Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein

Integrative Cancer Therapies, 2022
Owing to the crucial role of Src in cancer metastasis, interruption of Src and its signaling has been considered a promising strategy for cancer metastasis treatment.
Putthaporn Kaewmeesri MS, Piman Pocasap PhD, Veerapol Kukongviriyapan PhD, Auemduan Prawan PhD, Sarinya Kongpetch PhD, Laddawan Senggunprai PhD   +5 more
doaj   +1 more source

Capecitabine as second-line treatment for metastatic cholangiocarcinoma: A report of two cases [PDF]

, 2002
Background: The management of recurrent, metastatic cholangiocarcinoma still remains a problem since this tumor entity is classified as chemotherapy-resistant.
Schalhorn, A., Stemmler, Joachim, Heinemann, Volker   +2 more
core   +1 more source

Targeting Fatty Acid Synthase Modulates Metabolic Pathways and Inhibits Cholangiocarcinoma Cell Progression

Frontiers in Pharmacology, 2021
An aberrant regulation of lipid metabolism is involved in the pathogenesis and progression of cancer. Up-regulation of lipid biosynthesis enzymes, including acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and HMG-CoA reductase (HMGCR), has been ...
Jittima Tomacha, Jittima Tomacha, Hasaya Dokduang, Sureerat Padthaisong, Nisana Namwat, Nisana Namwat, Poramate Klanrit, Poramate Klanrit, Jutarop Phetcharaburanin, Jutarop Phetcharaburanin, Arporn Wangwiwatsin, Arporn Wangwiwatsin, Tueanjit Khampitak, Supinda Koonmee, Supinda Koonmee, Attapol Titapun, Attapol Titapun, Apiwat Jarearnrat, Apiwat Jarearnrat, Narong Khuntikeo, Narong Khuntikeo, Watcharin Loilome, Watcharin Loilome   +22 more
doaj   +1 more source