Results 91 to 100 of about 407,583 (390)

Accuracy of a faecal immunochemical test in patients under colonoscopy surveillance of colorectal adenoma and cancer

Upsala Journal of Medical Sciences, 2023
Background: Surveillance of colorectal neoplasia place great strain on colonoscopy resources, and faecal immunochemical tests (FIT) are under-investigated for this purpose.
Louise Olsson, Daniel Sjöberg
doaj   +1 more source

Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]

, 1998
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R., Brinck, U., Gabius, Hans-Joachim, Korabiowska, M.   +3 more
core   +1 more source

The somatic mutation landscape of premalignant colorectal adenoma

Gut, 2017
Objective There are few studies which characterised the molecular alterations in premalignant colorectal adenomas. Our major goal was to establish colorectal adenoma genome atlas and identify molecular markers of progression from colorectal adenoma to ...
Shu-Hong Lin, G. Raju, C. Huff, Y. Ye, J. Gu, Jiun-Sheng Chen, M. Hildebrandt, Han Liang, D. Menter, Jeffery B. Morris, E. Hawk, J. Stroehlein, A. Futreal, S. Kopetz, L. Mishra, Xifeng Wu   +15 more
semanticscholar   +1 more source

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

Advanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou, Meijing Wang, Shunji Liu, Limei Gu, Shijia Liu, Qianming Du, Tianyi Zhang, Yinuo Ma, Lixin Zhao, Jiaming Wang, Qiang Xu, Tingsheng Ling, Haibo Cheng, Hongqi Chen, Yang Sun   +14 more
wiley   +1 more source

Goitre and Iodine Deficiency in Europe [PDF]

, 1985
The prevalence of endemic iodine-deficiency goitre in Europe has been reduced in many areas by the introduction of iodination programmes. Recent reports, however, show that goitre remains a significant problem and that its prevalence has not decreased in
Beckers, C., Bürgi, H., Escobar del Rey, F., Gembicki, M., Koutras, D. A., Lamberg, B. A., Langer, P., Lazarus, J. H., Querido, A., Scriba, Peter Christian, Thilly, C., Vigneri, R.   +11 more
core   +4 more sources

Engineering Bacteria as Living Therapeutics in Cancer Therapy

Advanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen, Jiaqi Chen, Yixuan Chen, Wenxuan Yuan, Jiao Zhang, Guoqing Wang, Zhuojun Dai   +6 more
wiley   +1 more source

Protein Signatures of Parathyroid Adenoma according to Tumor Volume and Functionality [PDF]

Endocrinology and Metabolism
Background Parathyroid adenoma (PA) is a common endocrine disease linked to multiple complications, but the pathophysiology of the disease remains incompletely understood.
Sung Hye Kong, Jeong Mo Bae, Jung Hee Kim, Sang Wan Kim, Dohyun Han, Chan Soo Shin   +5 more
doaj   +1 more source

Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Group‐specific component protein (GC) promotes perineural invasion (PNI) in pancreatic ductal adenocarcinoma (PDAC) by activating Schwann cell dedifferentiation and by enhancing tumor–Schwann cell chemoattraction, independently of vitamin D transport. Integrin β1 (ITGB1) functions as a GC receptor in both cancer cells and Schwann cells.
Shan Zhang, Luju Jiang, Shuqi Cai, Zheqi Weng, Yuheng Zhu, Zhi‐Wei Cai, Hui Li, Qing Li, Li‐Peng Hu, Hong‐Fei Yao, Rong Hua, Yu Zhao, Dongxue Li, Xiao‐Mei Yang, Jun‐Feng Zhang, Shu‐Heng Jiang   +15 more
wiley   +1 more source

CO2 laser treatment for vulvar syringoma: a case report [PDF]

Surgical & Cosmetic Dermatology
Syringoma is a rare benign adnexal tumor of the intraepidermal eccrine duct of unknown etiology. It is typically characterized by multiple, bilateral, yellow-brownish or skin-colored papules measuring 1-5 mm.
Giovana Junqueira Gerbasi, Panny Rushaster Cordeiro de Albuquerque, Dayane de Assis Pereira Hansen Cavalheiro, Ana Carolina Silva Chuery, Neila Maria de Góis Speck   +4 more
doaj   +1 more source

A rare case report of hypertrophic cardiomyopathy induced by catecholamine-producing tumor [PDF]

, 2018
RATIONALE: Catecholamine-producing tumors are rare, occurring in less than 0.2% of patients with hypertension, but can have relevant cardiovascular morbidity and mortality. PATIENT CONCERNS: A 37-year-old woman presented with a history of dyspnea, chest
Bisogni, Valeria, Bonvicini, Maria, Ciardi, Antonio, Concistré, Antonio, De Toma, Giorgio, Frustaci, Andrea, Iannucci, Gino, Letizia, Claudio, Mezzadri, Martina, Oliviero, Gaia, Olmati, Federica, Petramala, Luigi, Saracino, Vincenza   +12 more
core   +1 more source