Results 71 to 80 of about 158,214 (317)

Histopathological and Immunohistochemical Characterization of Sebaceous Adenoma and Epithelioma in Dogs

Animals
Sebaceous gland tumors are neoplasms originating from the sebaceous gland and are the third most common type of skin tumor, accounting for 21–35% of all cutaneous neoplasms in dogs.
Sanggu Kim, Preeti Kumari Chaudhary, Sachin Upadhayaya, Kwang Won Seo, Soochong Kim   +4 more
doaj   +1 more source

RNF43 Is an Early and Specific Mutated Gene in the Serrated Pathway, With Increased Frequency in Traditional Serrated Adenoma and Its Associated Malignancy

, 2017
RNF43 is an E3 ligase that suppresses the Wnt/beta-catenin signaling pathway and is frequently mutated in microsatellite-unstable colorectal carcinoma. To investigate the pathogenetic role of RNF43 in the serrated pathway, we conducted mutation analysis ...
Tsai, Jia-Huei;Liau, Jau-Yu;Yuan, Chang-Tsu;Lin, Yu-Lin;Tseng, Li-Hui;Cheng, Mei-Ling;Jeng, Yung-Ming, 鄭永銘;曾麗慧;林育麟;蔡佳惠;廖肇裕   +1 more
core   +1 more source

The interplay between p53 and p21 tumor suppressor proteins in the transformation of colorectal adenoma to carcinoma [PDF]

, 2008
DOAJ - Directory of Open Access Journals, 2008This study was carried out for evaluating the interplay of p53, p21 and Ki-67 proteins along the colorectal adenoma-carcinoma oncogenic transformation sequel.
Mahdi, L. K., Al-jeboori, T., Abubaker, F., Al-jeboori, Tarik R., Abbas, K., Hafidh, R. R., Al-jeboori, T. R., Abdulamir, A. S., Hafidh, Rand Riadh, Abdulamir, Ahmed Sahib, Abu bakar, F., Abubaker, Fatimah, Abbas, Kamir A., Abdulamir, A., Khalid Mahdi, Laila, Hafidh, R., Abbas, K. A., Mahdi, L.   +17 more
core   +1 more source

β-Catenin Activated Hepatocellular Adenoma: A Report of Three Cases in Korea

Gut and Liver, 2014
Background/AimsUpregulated CD64 expression on neutrophils is the most useful marker for acute bacterial infections and systemic inflammation. However, it is unknown whether CD64 is involved in the pathogenesis of acute pancreatitis (AP).
doaj   +1 more source

Sistema epidemiológico de regisro de tumores de hipófisis en el Centro Médico Docente La Trinidad. Período 2017-2020

Revista Científica CMDLT, 2022
Los tumores de hipófisis representan la forma más frecuente de tumor intracraneal en 14.7% . La proliferación excesiva y descontrolada son de un origen monoclonal, predominio benigno y crecimiento lento, pero pueden tener significativa morbilidad y ...
José Javier Orozco Barcos , Jhoskar Eduardo Natera García , Paul Camperos , Andrés Ricardo Ortega Mata   +3 more
doaj   +2 more sources

Living at genetic risk: The patient experience of Lynch syndrome

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome is a germline cancer predisposition syndrome caused by a variant in one of four genes. Lynch syndrome places individuals at significantly higher risk for a range of cancers, especially colorectal and endometrial. Depending on which gene is affected, the risk of ovarian, gastric, small bowel, pancreatic, biliary urothelial, brain,
Nicola Reents, Georgina Hoffmann, Kelly Kohut   +2 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Artificial Intelligence in Colonoscopy Surveillance for Lynch Syndrome: Emerging Evidence, Lessons Learned From Average‐Risk Populations, and Future Directions

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome and is characterized by an accelerated adenoma‐carcinoma sequence, a relatively higher prevalence of flat and subtle CRC precursor lesions, and exceptionally high adenoma miss rates despite intensive colonoscopy surveillance.
Robert Hüneburg, Querijn N. E. van Bokhorst, Evelien Dekker, Jacob Nattermann   +3 more
wiley   +1 more source

Blood‐Based Circulating Tumor DNA Assays for Early Colorectal Cancer Detection: A Systematic Review of Performance in Asymptomatic Screening Populations

International Journal of Cancer, EarlyView.
Early detection of colorectal cancer via population‐based screening programs can reduce incidence and mortality, but current screening approaches are limited. This systematic review evaluated the screening potential of blood‐based circulating tumor DNA assays in asymptomatic screening populations.
Caroline Ledertoug Kahn, Maria Wissing Rasmussen, Jakob Kleif, Inge Søkilde Pedersen, Christina Therkildsen   +4 more
wiley   +1 more source

Derivation and Validation of a Predictive Model for Advanced Colorectal Neoplasia Among Average‐Risk Adults in China

International Journal of Cancer, EarlyView.
Efficient pre‐colonoscopy risk stratification tools are needed, especially in China. Using multicenter colorectal cancer screening data from Shandong Province, the authors developed and validated a risk prediction model for advanced colorectal neoplasia in asymptomatic individuals using sociodemographic characteristics, lifestyle factors, and medical ...
Yan Liu, Yanxiu Liu, Yukun Feng, Boyu Liu, Wenxuan Yan, Nan Zhang, Youhua Lu   +6 more
wiley   +1 more source