Results 51 to 60 of about 158,214 (317)

Efficacy and safety of cold forceps polypectomy utilizing the jumbo cup: a prospective study.

, 2021
滋賀医科大学博士（医学）pdfBackground/aims: There are few prospective studies on cold forceps polypectomy (CFP) using jumbo cup forceps. Therefore, we examined patients with diminutive polyps (5 mm or smaller) treated with CFP using jumbo cup forceps to achieve an ...
長谷川, 大, HASEGAWA, Hiroshi
core   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]

, 2001
Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian, Heinzlmann, M., Neynaber, S., Heldwein, W.   +3 more
core   +1 more source

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Carcinoma ex pleomorphic adenoma in minor salivary glands of the anterior tongue: A case report [PDF]

, 2013
Carcinoma ex pleomorphic adenoma (CEPA) is defined as a pleomorphic adenoma from which an epithelial malignancy is derived. Most cases of CEPA occur in parotid glands, and CEPA arising in minor salivary glands is rare. We report an extremely rare case of
Matsutani, Kouhei, Kawano, Toshihiro, Kawasaki, Goro, Fujita, Shuichi, Ikeda, Tohru, Yamada, Shin-ichi, Umeda, Masahiro, Yanamoto, Souichi, Rokutanda, Satoshi   +8 more
core   +1 more source

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

Relationship Between Gastric Helicobacter pylori Infection and Colorectal Polyps: A Retrospective Cohort Study [PDF]

Iranian Journal of Colorectal Research
Background: Infection with Helicobacter pylori (H. pylori) infection is one of the most prevalent bacterialinfections worldwide. It is well-established as a contributing factor to various conditions, including chronicgastritis, peptic ulcers, and gastric
Furkan Karahan, Hüseyin Taş
doaj   +1 more source

Adenoma of the Umbilicus [PDF]

The American Journal of the Medical Sciences, 1904
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openaire   +2 more sources

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source

A Case of Mediastinal Parathyroid Adenoma

, 2015
Parathyroid adenomas are the most important cause of primary hyperparathyroidism. The diagnosis of primary hyperparathyroidism is established based on the combination of elevated serum calcium and parathyroid hormone levels.
Erkan Akar
core   +1 more source