K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]
Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian +3 more
core +2 more sources
Change in the incidence and anatomic distribution of colorectal adenoma and cancer over a period of 20 years: A single center experience [PDF]
Background/Aim. In recent years, many studies have demonstrated a proximal shift in the distribution of adenomas and colorectal cancers. The aim of this study was to investigate whether there are differences in the incidence and anatomical distribution ...
Milovanović-Alempijević Tamara +8 more
doaj +1 more source
Sporadic colorectal cancer is characterized by a multistep progression from normal epithelium to precancerous low-risk and high-risk adenomas to invasive cancer.
Tanja Gumpenberger +11 more
doaj +1 more source
Awareness of lifestyle and colorectal cancer risk:findings from the BeWEL study [PDF]
It is estimated that 47% of colorectal cancers (CRC) could be prevented by appropriate lifestyles. This study aimed to identify awareness of the causes of CRC in patients who had been diagnosed with a colorectal adenoma through the Scottish bowel ...
Steele, Robert J. C. +10 more
core +1 more source
The Occurrence of Primary Hepatic Adenoma in Deceased Donor Renal Transplant Recipient
Main findings: We reported a case of new-onset, multi-focal hepatic adenoma in an 18 year-old man with no classic risk factors occurring forty months after a renal transplant from a cadaver donor.
胡瑞恒;鄭永銘;蔡孟昆;何明志 +1 more
core +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Study protocol for BeWEL: The impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas [PDF]
Background: Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second highest cause of cancer death in the UK. Most cases occur in people over 50 years and CRC often co-exists with other lifestyle related disorders including ...
Belch, Jill J F +69 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Causal associations of COVID‐19 on neurosurgical diseases risk: a Mendelian randomization study
Many researchers have explored the potential association between one neurosurgical disease and coronavirus disease 2019 (COVID-19), but few systematically analyzed the association and causality between COVID-19 and various neurosurgical diseases.
Lirui Dai +3 more
doaj +1 more source
Actualización sobre mecanismos de tumorogénesis hipofisaria
Los adenomas hipofisarios son neoplasias intracraneales que surgen de las células del lóbulo anterior de la glándula, benignos y de crecimiento lento en su gran mayoría.
Laura Anahi Cecenarro +2 more
doaj +1 more source

