Results 71 to 80 of about 152,783 (321)
Animal Models and Experimental Medicine, EarlyView.The exon 16 of the mouse Apc gene was targeted with CRISPR/Cas9 system and a novel Apc knockout mouse model was generated by creating a frameshift mutation at codon 750 (ApcΔ750). The polyp number, polyp distribution and the overall survival of mice carrying the ApcΔ750 allele significantly differs between the F8‐FVB‐ApcΔ750 and F4‐B6;FVB‐ApcΔ750 mouse
Sarp Uzun +7 more
wiley +1 more source
Pituitary Adenoma Segmentation [PDF]
arXiv, 2011 Sellar tumors are approximately 10-15% among all intracranial neoplasms. The most common sellar lesion is the pituitary adenoma. Manual segmentation is a time-consuming process that can be shortened by using adequate algorithms. In this contribution, we present a segmentation method for pituitary adenoma.
arxiv
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian +5 more
wiley +1 more source
Archives of Medical Science, 2019 Introduction Colonoscopy has been widely regarded as the gold standard in colorectal cancer (CRC) screening. Within recent years different endoscopic imaging techniques have been introduced to improve the quality of colonoscopy.
Maciej Matyja +5 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo +6 more
wiley +1 more source
Adenomas produtores de TSH: Relato de caso [PDF]
Arquivos de Neuro-Psiquiatria, 2002 Descrevemos um caso raro de adenoma hipofisário produtor de TSH em uma paciente com quadro de hipertireoidismo, que após quatro anos desenvolveu hemianopsia bitemporal.
Oswaldo Inácio Tella Jr +3 more
doaj +1 more source
Adenomatous Tumors of the Middle Ear: A Literature Review
International Archives of Otorhinolaryngology, 2017 Introduction Neuroendocrine adenomas of the middle ear (NAME) are uncommon causes of middle ear masses. Mostly limited to case reports and small series, the literature is poor in providing an overall assessment of these tumors.
Flavia Amarante Cardoso +4 more
doaj +1 more source
Pituitary Apoplexy May Be Mistaken for Temporal Arteritis
European Journal of Case Reports in Internal Medicine, 2019 Pituitary apoplexy is a rare endocrine emergency, characterized by a sudden increase in pituitary gland volume secondary to acute ischaemic infarction or haemorrhage of the pituitary gland, usually in the presence of a pituitary adenoma.
Bárbara Pedro +2 more
doaj +1 more source
Deep-Learning for Classification of Colorectal Polyps on Whole-Slide Images [PDF]
arXiv, 2017 Histopathological characterization of colorectal polyps is an important principle for determining the risk of colorectal cancer and future rates of surveillance for patients. This characterization is time-intensive, requires years of specialized training, and suffers from significant inter-observer and intra-observer variability. In this work, we built
arxiv
On optimal two-stage testing of multiple mediators [PDF]
arXiv, 2020 Mediation analysis in high-dimensional settings often involves identifying potential mediators among a large number of measured variables. For this purpose, a two-step familywise error rate procedure called ScreenMin has been recently proposed (Djordjilovi\'c et al. 2019).
arxiv