Results 81 to 90 of about 417,233 (389)

Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]

, 2001
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Gloddek, Jutta, Hopfner, Ursula, Lohrer, Penny, Losa, Marco, Pagotto, Uberto, Renner, Ulrich, Stalla, Günter K., Uhl, Eberhard   +7 more
core   +1 more source

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, EarlyView.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

A rare presentation of adrenal adenoma in infancy: isolated Cushing`s syndrome

The Turkish Journal of Pediatrics, 2020
Adrenocortical tumors are rare in children. Most of these tumors present with endocrinological manifestations, majority of which with virilizing features alone or in combination with over production of other adrenal hormones.
Oğuzhan Şal, Gülçin Yeğen, Pelin Oğuzkurt   +2 more
doaj   +1 more source

Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions [PDF]

, 2016
An exact classification of precancerous stages of colorectal polyps might improve therapy and patients´ outcome. Here we investigate the association between grade of dysplasia and Matrix metalloproteinase-13 (MMP-13) expression in 137 biopsies from ...
Churin, Yuri, Gattenlöhner, Stefan, Roderfeld, Martin, Roeb, Elke, Sheridan, Diana, Tschuschner, Annette, Wernicke, Anna-Katharina, Windhorst, Anita   +7 more
core   +1 more source

Safety and Feasibility of Laparoscopic and Endoscopic Cooperative Surgery With Endoscopic Submucosal Dissection for Large Superficial Non‐Ampullary Duodenal Epithelial Tumors

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background and Aims Endoscopic submucosal dissection (ESD) for large superficial non‐ampullary duodenal epithelial tumors (SNADETs) poses substantial technical challenges, primarily because of a heightened risk of adverse events (AEs). Laparoscopic and endoscopic cooperative surgery (D‐LECS) was introduced to address these risks, with recent ...
Masaru Hayami, Shoichi Yoshimizu, Naoki Miyazaki, Shintaro Yamamoto, Hiroyuki Yamamoto, Motonari Ri, Rie Makuuchi, Tomoyuki Irino, Manabu Takamatsu, Souya Nunobe   +9 more
wiley   +1 more source

Accuracy of a faecal immunochemical test in patients under colonoscopy surveillance of colorectal adenoma and cancer

Upsala Journal of Medical Sciences, 2023
Background: Surveillance of colorectal neoplasia place great strain on colonoscopy resources, and faecal immunochemical tests (FIT) are under-investigated for this purpose.
Louise Olsson, Daniel Sjöberg
doaj   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S., Allolio, B., Beuschlein, Felix, Chrousos, G. P., Jaursch-Hancke, C., Karl, M., Reincke, Martin, Travis, W.   +7 more
core  

The somatic mutation landscape of premalignant colorectal adenoma

Gut, 2017
Objective There are few studies which characterised the molecular alterations in premalignant colorectal adenomas. Our major goal was to establish colorectal adenoma genome atlas and identify molecular markers of progression from colorectal adenoma to ...
Shu-Hong Lin, G. Raju, C. Huff, Y. Ye, J. Gu, Jiun-Sheng Chen, M. Hildebrandt, Han Liang, D. Menter, Jeffery B. Morris, E. Hawk, J. Stroehlein, A. Futreal, S. Kopetz, L. Mishra, Xifeng Wu   +15 more
semanticscholar   +1 more source

Outcomes of Pancreas‐Sparing Total Duodenectomy for Severe Duodenal Polyposis in Patients With Familial Adenomatous Polyposis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Spigelman stage IV duodenal polyposis (SP‐stage IV DP) is associated with high duodenal cancer risk in patients with familial adenomatous polyposis (FAP). This study evaluated the surgical and oncological outcomes of pancreas‐sparing total duodenectomy (PSTD) as a surgical prophylaxis for severe duodenal polyposis in FAP.
Takehiro Shiraishi, Hideyuki Ishida, Takatoshi Matsuyama, Noriyasu Chika, Yoshiko Mori, Norimichi Chiyonobu, Youichi Kumagai, Ibuki Fujinuma, Toshiro Ogura   +8 more
wiley   +1 more source

Forty-Year Analysis of Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis: An Updated Overview [PDF]

, 2015
C.R.C. was funded by the Derek Willoughby Fund for Inflammatory Research. A.L.H. and T.A.G.
Ailsa L Hart, Alan Askari, Bernstein, Blackstone, Braakhuis, Brian P Saunders, Chang-Ho Ryan Choi, Connell, Connell, Eaden, Greenstein, Gui Han Lee, Hurlstone, Janindra Warusavitarne, Kiesslich, Marion, Matthew D Rutter, Morgan Moorghen, Nugent, Odze, Odze, Riddell, Rubin, Rutter, Rutter, Rutter, Siwan Thomas-Gibson, Trevor A Graham, van Schaik, van Schaik, Vieth, Wanders   +31 more
core   +1 more source