Results 81 to 90 of about 7,755,431 (290)

Gene-Specific Detection Rate of Adenomas and Advanced Adenomas in Lynch Syndrome

Gastroenterology
Colonoscopy is expected to reduce colorectal cancer (CRC) incidence in Lynch syndrome (LS) by detecting and removing adenomas. The existence of gene-specific differences in adenoma detection has been proposed yet remains insufficiently explored.
Sánchez Brualla, Alicia, Castillo Iturra, Joaquín, Balmaña, Judith, Brunet, Joan, Castells Sánchez, Alba, Capellá, G. (Gabriel), Ladabaum, Uri, Dekker, Evelien, Moreira, Luciana, Pellisé Urquiza, Maria, Balaguer Prunés, Francesc, López Fernández, Adrià, Salces, Inmaculada, Picó, María Dolores, Rivas, Laura, Bujanda, Luis, Garzon, Marta, Pizarro, Angeles, Martinez de Castro, Eva, Roos, V.H., Dueñas, Nuria, Pineda Riu, Marta, Moreno Calle, Lorena, Rodríguez Alonso, Lorena, Ramon y Cajal, Teresa, Llort, Gemma, Piñol, Virginia, López Arias, María .Jesús, Poves, Carmen, Garau, Catalina, Rodríguez Alcalde, Daniel, Herraiz, Maite, Álvarez Urrutia, Cristina, Dacal, Andrés, Carrillo Palau, Marta, Cid, Lucía, Ponce, Marta, Barreiro Alonso, Eva, Saperas, Esteban, Aguirre, Elena, Bastiaansen, B., Ocaña, Teresa, Carballal, Sabela, Rivero Sánchez, Liseth, Ortiz Zúñiga, Oswaldo, Daca-Alvarez, Maria, Prat Galito, Ricard, Bessa, Xavier, Cubiella, Joaquin, Jover, Rodrigo, Rodríguez Moranta, Francisco   +50 more
openaire   +5 more sources

Sa1061 REFINING A CONVERSION FACTOR FOR ACCURATELY ESTIMATING THE ADENOMA DETECTION RATE FOR BOTH HIGH AND LOW POLYP DETECTORS

, 2018
Determining the adenoma detection rate (ADR) is one key performance indicator for ensuring quality colonoscopy. However, it is time consuming and laborious to determine, as often the pathology and the endoscopy data are not electronically interfaced ...
Dianne Jones, Wiyang Szetoo, Sarah Stanley, Leslie Wiggins, Stanley, Sarah, McIvor, Carolyn, Szetoo, Wiyang, Jones, Dianne, Wiggins, Leslie, Carolyn McIvor   +9 more
core   +1 more source

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

Advanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song, Youwen Qin, Jiahui Luo, Liping Liu, Chenyu Luo, Yinbin Qiu, Yiyi Zhong, Huanzi Zhong, Kui Wu, Meng Ni, Dong Wu, Min Dai, Shida Zhu, Hongda Chen   +13 more
wiley   +1 more source

ORIGINAL ARTICLE: Will An Additional Observer Enhance Adenoma Detection During Colonoscopy? [PDF]

Journal of Krishna Institute of Medical Sciences University, 2012
Background: Due to varied level of experience, the detection rate of adenoma on colonoscopy is different. In presence of both fellows and attending the incidence rates of adenoma are shown to increase in a small study reported by Rogart et al [4].
Kevin D Mullen, Puja Karanth, Madhusudhan Sanaka, Nirav Shah, Ravi K Prakash, Roy D Ferguson   +5 more
doaj  

Endocuff-Assisted Colonoscopy—A Novel Accessory in Improving Adenoma Detection Rate: A Review of the Literature [PDF]

, 2016
Endocuff (Arc Medical Design) is a U.S. Food and Drug Administration-approved device that is attached like a cap to the distal tip of the colonoscope; it is used to improve adenoma detection rates during colonoscopy.
Emmanuel Ofori, Rashmee Patil, Mel A. Ona, Madhavi Reddy   +3 more
core   +1 more source

Intermittent Fasting Reduces Taurine Availability and Promotes Antitumor Immunity Through PERK Attenuation‐Associated Paraptosis‐Like Cell Death in Colorectal Cancer

Advanced Science, EarlyView.
This study identifies reduced taurine availability as a mediator of intermittent fasting in colorectal cancer and shows that taurine interacts with GRP78 to maintain PERK abundance post‐transcriptionally. It further shows that taurine depletion destabilizes PERK, induces immunogenic paraptosis, remodels the tumor microenvironment toward a CD8+ T cell ...
Baohui Song, Sikei Kam, Jingyi Liu, Rui Lv, Xucheng Huo, Zhanghan Chen, Yuelun Dong, Shilun Cai, Bing Li, Ruobing Ren, Yunshi Zhong, Mingyan Cai   +11 more
wiley   +1 more source

New Colonoscopy Devices to Improve Colon Neoplasm Detection

The Korean Journal of Gastroenterology, 2016
Early detection and removal of adenomatous polyps can prevent the development of colorectal cancer. However, it is fairly common—up to 20%—for polyps to be undetected in a colonoscopy due to poor visualization of the proximal aspect of colonic folds and ...
Sung Jae Shin
doaj   +1 more source

Mitochondrial Localization of Cx26 Promotes Colorectal Cancer Malignancy and Exposes a Fatal Vulnerability to Drug Targeting

Advanced Science, EarlyView.
Mitochondrial localization of Cx26 emerges as a double‐edged sword in colorectal cancer. PIMT‐mediated methylation of Cx26 promotes its mitochondrial localization and stability. Mitochondrial Cx26 then facilitates ER‐mitochondria communication and Ca2+ signaling, thereby promoting metastatic progression. Bortezomib exploits this malignant adaptation by
Jie Wang, Lu Chen, Jia Qin, Xiaoning Wang, Sunlan Ye, Ning An, Mei Bai, Yan Shen, Xuefeng Wu, Qiang Xu   +9 more
wiley   +1 more source

Artificial intelligence-based computer-aided detection systems for adenomas during colonoscopy: a systematic review and Bayesian network meta-analysis

Frontiers in Artificial Intelligence
Background and aimsArtificial intelligence-based computer-aided detection (CADe) systems have been developed to enhance the adenoma detection rate (ADR) during colonoscopy, but their performance is unknown. We primarily aimed to compare the effectiveness
Zhenjia Fan, Danyan Li, Jixiang Liu, Yudi Zhuo, Shengsheng Zhang   +4 more
doaj   +1 more source

AI Dependence as a Longitudinal Governance Problem

AI &Innovation, EarlyView.
ABSTRACT Artificial intelligence governance typically focuses on whether people rely on AI appropriately during individual decisions. This Perspective addresses a different question: whether repeated AI use changes the capabilities and alternatives available to users and organisations over time.
Yiran Du
wiley   +1 more source