Results 71 to 80 of about 7,755,431 (290)

Defining adenoma detection rate benchmarks in average-risk male veterans

, 2018
Background and Aims Veterans have higher prevalence of colorectal neoplasia than non-veterans; however, it is not known whether specific Veterans Affairs (VA) adenoma detection rate (ADR) benchmarks are required.
Saito, Akira, Eckert, George J., Kahi, Charles J., El-Halabi, Mustapha M., Rex, Douglas K.   +4 more
core   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

Advanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok, Laura Činč Ćurić, Jernej Vajda, Silvia Schauer, Martin Wagner, Rudolf Stauber, Carolin Lackner, Karl Kashofer, Markus Plass, Giovanny Rodriguez Blanco, Ian R. Wanless, Uroš Maver, Katrin Panzitt, Boštjan Vihar   +13 more
wiley   +1 more source

The single-monitor trial: an embedded CADe system increased adenoma detection during colonoscopy: a prospective randomized study

Therapeutic Advances in Gastroenterology, 2020
Background: Computer-aided detection (CADe) of colon polyps has been demonstrated to improve colon polyp and adenoma detection during colonoscopy by indicating the location of a given polyp on a parallel monitor.
Peixi Liu, Pu Wang, Jeremy R. Glissen Brown, Tyler M. Berzin, Guanyu Zhou, Weihui Liu, Xun Xiao, Ziyang Chen, Zhihong Zhang, Chao Zhou, Lei Lei, Fei Xiong, Liangping Li, Xiaogang Liu   +13 more
doaj   +1 more source

Characterization of Human Pituitary Adenomas in Cell Cultures by Light And Electron Microscopic Morphology And Immunolabeling [PDF]

, 2005
The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens.
Bácsy, Ernő, Hegedűs, Balázs, Slowik, Felicia, Bálint, Katalin, Pásztor, Emil, Kerekes, Edit, Fazekas, Ilona   +6 more
core   +1 more source

Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target

Advanced Science, EarlyView.
Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen, Pingmei Huang, Ruizhi Tao, Fenfen Ji, Qinyao Wei, Lok Hin Ko, Lianxin Zhou, Huarong Chen, Alvin Cheung, Wei Kang, Ko Fai To, Jun Yu, Chi Chun Wong   +12 more
wiley   +1 more source

Quality in Colonoscopy: Beyond the Adenoma Detection Rate Fever

GE: Portuguese Journal of Gastroenterology, 2017
Background: Colonoscopy quality is a hot topic in gastroenterological communities, with several actual guidelines focusing on this aspect. Although the adenoma detection rate (ADR) is the single most important indicator, several other metrics are ...
Filipe Taveira, Miguel Areia, Luís Elvas, Susana Alves, Daniel Brito, Sandra Saraiva, Ana Teresa Cadime   +6 more
doaj   +1 more source

Higher adenoma detection rates with endocuff-assisted colonoscopy - a randomized controlled multicenter trial. [PDF]

PLoS ONE, 2014
The Endocuff is a device mounted on the tip of the colonoscope to help flatten the colonic folds during withdrawal. This study aimed to compare the adenoma detection rates between Endocuff-assisted (EC) colonoscopy and standard colonoscopy (SC).This ...
Martin Floer, Erwin Biecker, Rüdiger Fitzlaff, Hermann Röming, Detlev Ameis, Achim Heinecke, Steffen Kunsch, Volker Ellenrieder, Philipp Ströbel, Michael Schepke, Tobias Meister   +10 more
doaj   +1 more source

Factors associate with high adenoma detection rate: a tertiary centre experience [PDF]

, 2023
NTRODUCTION: Colorectal cancer (CRC) is the leading cancer among men and the second leading cancer among women in Malaysia. Colonoscopy is a gold standard modality for screening of CRC because it allows complete examination of the colon for the ...
Nik Muhamad Affendi, Nik Arsyad, Ho, Shiaw Hooi, Hashim, Mohd Badrul Hisyam   +2 more
core  

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

A prospective randomized study of colonoscopy using blue laser imaging and white light imaging in detection and differentiation of colonic polyps

Endoscopy International Open, 2019
Background and study aims Published data on blue laser imaging (BLI) for detection and differentiation of colonic polyps are limited compared to narrow band imaging (NBI).
Tiing Leong Ang, James Weiquan Li, Yu Jen Wong, Yi-Lyn Jessica Tan, Kwong Ming Fock, Malcolm Teck Kiang Tan, Andrew Boon Eu Kwek, Eng Kiong Teo, Daphne Shih-Wen Ang, Lai Mun Wang   +9 more
doaj   +1 more source