Results 51 to 60 of about 7,755,431 (290)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

The significance of retroflexion technique in the right colon on adenoma detection rates during colonoscopy

Journal of Coloproctology, 2019
Background and aim: Right colon adenomas can easily missed with significant adenoma miss rate particularly when they are located behind the haustral folds and anatomical flexures.
Mohamed S. EL Shahawy, Mohamed EL Fayoumy   +1 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Endoscopy Nurse Participation May Increase the Polyp Detection Rate by Second-Year Fellows during Screening Colonoscopies

Gut and Liver, 2012
Background/AimsThe aim of this study was to assess the effects of endoscopy nurse participation on polyp detection rate (PDR) and adenoma detection rate (ADR) of second-year fellows during screening colonoscopies.Methods : This was a single-center ...
doaj   +1 more source

Position change during colonoscopy improves caecal intubation rate, mucosal visibility, and adenoma detection in patients with suboptimal caecal preparation

, 2017
Introduction : Most colonoscopies are completed in the left lateral (LL) position but in cases of suboptimal caecal preparation, changing the patient’s position to supine (S) and, if needed, to right lateral (RL) improves caecal intubation rate, mucosal ...
Vijaypal Arya, Shashank Agarwal, Shikha Singh, Ashok Valluri, Oonagh Dowling, Kalpana Arya Gupta, Cristina Sison   +6 more
core   +1 more source

Supplementary Material for: Polyp Detection Rate as a Surrogate for Adenoma and Sessile Serrated Adenoma/Polyp Detection Rates

, 2020
Introduction: Quality measures for colonoscopy such as adenoma detection rate (ADR) have been proposed to be surveilled for ensuring minimum standards. However, its direct measurement is time consuming and often neglected.
Edwards S. (8434677), Yamamura T. (4150090), Ruszkiewicz A. (8434680), Fujishiro M. (5556926), Singh G. (4150960), Hirooka Y. (8434683), ZorronChengTaoPu L. (8434665), Rana K. (8434668), Burt A.D. (8434686), Krishnamurthi S. (8434671), Nakamura M. (3835381), Singh R. (4142539), Ovenden A. (8434674)   +12 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Evaluation of Artificial Intelligence: Computer-aided Detection of Colorectal Polyps

Journal of the Anus, Rectum and Colon
Objectives: Colonoscopy is the gold standard for screening cancer and precancerous lesions in the large intestine. Recently, remarkable advances in artificial intelligence (AI) have led to the development of various computer-aided detection (CADe ...
Yuya Hiratsuka, Takashi Hisabe, Kensei Ohtsu, Tatsuhisa Yasaka, Kazuhiro Takeda, Masaki Miyaoka, Yoichiro Ono, Takao Kanemitsu, Kentaro Imamura, Teruyuki Takeda, Satoshi Nimura, Kenshi Yao   +11 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Expert endoscopists with high adenoma detection rates frequently detect diminutive adenomas in proximal colon [PDF]

Endoscopy International Open, 2020
Abstract Background and study aims Adenoma detection rate (ADR) is an important quality indicator in colonoscopy, and improved ADR decreases the incidence of colorectal cancer. We investigated differences in polyp detection according to the endoscopist’s ADR.
Osamu Toyoshima, Toshihiro Nishizawa, Shuntaro Yoshida, Kazuma Sekiba, Yosuke Kataoka, Keisuke Hata, Hidenobu Watanabe, Yosuke Tsuji, Kazuhiko Koike   +8 more
openaire   +3 more sources