Results 31 to 40 of about 7,755,431 (290)

K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]

, 2001
Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian, Heinzlmann, M., Neynaber, S., Heldwein, W.   +3 more
core   +2 more sources

Does Metformin Affect The Incidence of Colonic Polyps and Adenomas in Patients with Type 2 Diabetes Mellitus? [PDF]

Intestinal Research, 2014
Background/AimsColorectal cancer (CRC) develops from colonic adenomas. Type 2 diabetes mellitus (DM) is associated with a higher risk of CRC and metformin decreases CRC risk.
Youn Hee Cho, Bong Min Ko, Shin Hee Kim, Yu Sik Myung, Jong Hyo Choi, Jae Pil Han, Su Jin Hong, Seong Ran Jeon, Hyun Gun Kim, Jin Oh Kim, Moon Sung Lee   +10 more
doaj   +1 more source

Risk of advanced colorectal neoplasia according to age and gender. [PDF]

, 2011
Colorectal cancer (CRC) is one of the leading causes of cancer related morbidity and death. Despite the fact that the mean age at diagnosis of CRC is lower in men, screening by colonoscopy or fecal occult blood test (FOBT) is initiated at same age in ...
Alexander Crispin, Burkhard Göke, Wagner, A., Crispin, Alexander, Göke, Burkhard, Frank T. Kolligs, Frank T Kolligs, Kolligs, Frank T., Andreas Wagner, Kolligs, F. T., Mansmann, Ulrich, Ulrich Mansmann, Wagner, Andreas, Axel Munte, Munte, A., Munte, Axel   +15 more
core   +2 more sources

Improved detection of adenomas and sessile serrated polyps is maintained with continuous audit of colonoscopy

BMJ Open Gastroenterology, 2020
Background The audit process may help improve performance indicators for colonoscopy quality but it is unclear whether this is sustained over several years.Methods 44138 procedures for 28 endoscopists from 2004 to 2019 were analysed for polyp detection ...
Philip Wong, Alan Gordon Fraser, Toby Rose, Mark Lane, Paul Frankish   +4 more
doaj   +1 more source

Nurse Participation in Colonoscopy Observation versus the Colonoscopist Alone for Polyp and Adenoma Detection: A Meta-Analysis of Randomized, Controlled Trials

Gastroenterology Research and Practice, 2016
The role of nurse participation (NP) in colonoscopy observation for polyp and adenoma detection is unclear. This study aimed to evaluate whether nurse participation can improve polyp and adenoma detection. Patients and Methods.
Lei Xu, Yu Zhang, Haojun Song, Weihong Wang, Sijie Zhang, Xiaoyun Ding   +5 more
doaj   +1 more source

The Impact of Computer-aided Detection Technology in Adenoma Detection Rate Among Experienced Endoscopists in the Community Setting. [PDF]

J Community Hosp Intern Med Perspect
Adenoma detection rate (ADR) is a key quality metric in screening colonoscopies. An adenoma detection rate of greater than 30% reduces the incidence of colorectal carcinoma (CRC). Furthermore, studies have demonstrated an inverse relationship between ADR
Ahsan M, Anderson Z, Jarbath M, Bakr M, Phillips RW.   +4 more
europepmc   +2 more sources

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

The ADENOMA Study. Accuracy of Detection using Endocuff Vision™ Optimization of Mucosal Abnormalities: study protocol for randomized controlled trial

Endoscopy International Open, 2016
Background: Colonoscopy is the gold standard investigation for the diagnosis of bowel pathology and colorectal cancer screening. Adenoma detection rate is a marker of high quality colonoscopy and a high adenoma detection rate is associated with a lower ...
Roisin Bevan, Wee Sing Ngu, Brian P. Saunders, Zacharias Tsiamoulos, Paul Bassett, Zoe Hoare, Colin J. Rees   +6 more
doaj   +1 more source

Actual and estimated adenoma detection rates: a 2‐year monocentric colonoscopic screening outcome in Shenzhen, China

JGH Open, 2020
Background and Aim While adenoma detection rate (ADR) is an important quality metric for screening colonoscopy, it remains difficult to be accessed due to the lack of integrated endoscopy and pathology databases.
Li Zeng, Eng G. Chua, Ying Xiong, Shihua Ding, Hui Ai, Zhibo Hou, Mun F. Loke, Khean L. Goh, Chin Y. Tay, Barry J. Marshall, Fuqiang Zhu, Dayong Sun   +11 more
doaj   +1 more source

Artificial intelligence for colorectal neoplasia detection during colonoscopy: a systematic review and meta-analysis of randomized clinical trialsResearch in context

EClinicalMedicine, 2023
Summary: Background: The use of artificial intelligence (AI) in detecting colorectal neoplasia during colonoscopy holds the potential to enhance adenoma detection rates (ADRs) and reduce adenoma miss rates (AMRs).
Shenghan Lou, Fenqi Du, Wenjie Song, Yixiu Xia, Xinyu Yue, Da Yang, Binbin Cui, Yanlong Liu, Peng Han   +8 more
doaj   +1 more source