Results 91 to 100 of about 61,617 (230)

Adenosine A2a receptor promotes lymphangiogenesis and lymph node metastasis

OncoImmunology, 2019
The formation of new lymphatic vessels, or lymphangiogenesis, is a critical step of the tissue repair program. In pathological conditions involving chronic inflammation or tumorigenesis, this process is often dysregulated and can contribute to disease ...
Bertrand Allard, Isabelle Cousineau, David Allard, Laurence Buisseret, Sandra Pommey, Pavel Chrobak, John Stagg   +6 more
doaj   +1 more source

The Role Played by Adenosine in Modulating Reflex Sympathetic and Pressor Responses Evoked by Stimulation of TRPV1 in Muscle Afferents

Cellular Physiology and Biochemistry, 2016
Background/Aims: Activation of metabolite-sensitive transient receptor potential vanilloid type 1 (TRPV1) receptors (capsaicin receptors) in afferent nerves of the hindlimb muscles of rats increases renal sympathetic nerve activity (RSNA) and blood ...
Jihong Xing, Jianhua Li
doaj   +1 more source

Adaptations to hypoxia in the vertebrate retina

The Journal of Physiology, Volume 603, Issue 21, Page 6517-6531, November 1, 2025.
Abstract figure legend Most animals, including mammals, are susceptible to the damaging effects of hypoxia or ischaemia, where the result is neuronal cell death in the brain. By contrast, some neurons of the mammalian retina are less sensitive to hypoxia. In both brain and retina, neurons may survive if first preconditioned with ischaemia.
Michael G. Jonz
wiley   +1 more source

Ecto-5'-Nucleotidase (CD73)-Mediated Formation of Adenosine Is Critical for the Striatal Adenosine A2A Receptor Functions [PDF]

, 2013
Elisabete Augusto, Marco Matos, Jean Sévigny, Ali El‐Tayeb, Margaret S. Bynoe, Christa E. Müller, Rodrigo A. Cunha, Jiang‐Fan Chen   +7 more
openalex   +1 more source

The belated US FDA approval of the adenosine A2A receptor antagonist istradefylline for treatment of Parkinson’s disease

Purinergic Signalling Purinergic Signalling, 2020
Jiang-fan Chen, R. Cunha
semanticscholar   +1 more source

Increased orbitofrontal brain activation after administration of a selective adenosine A2A antagonist in cocaine dependent subjects

Frontiers in Psychiatry, 2012
Background: Positron Emission Tomography imaging studies provide evidence of reduced dopamine function in cocaine dependent subjects in the striatum, which is correlated with prefrontal cortical glucose metabolism, particularly in the orbitofrontal ...
F. Gerard eMoeller, Joel L Steinberg, Scott D Lane, Kimberly L Kjome, Liangsuo eMa, Sergi eFerre, Joy eSchmitz, Charles E Green, Stephen I Bandak, Perry F Renshaw, Larry A Kramer, Ponnada A Narayana   +11 more
doaj   +1 more source

Aβ1-42 peptides blunt the adenosine A2A receptor-mediated control of the interplay between P2X7 and P2Y1 receptors mediated calcium responses in astrocytes

, 2022
Liliana Dias, Daniela Madeira, Rafael Dias, Ângelo R. Tomé, Rodrigo A. Cunha, Paula Agostinho   +5 more
openalex   +2 more sources

Adenosine A1-A2A receptor heteromers: new targets for caffeine in the brain [PDF]

, 2007
Sergi Ferré
openalex   +1 more source

Overactivity of neuronal adenosine A2A receptors accelerates neurodegeneration [PDF]

, 2019
Rodrigo A. Cunha
openalex   +1 more source

Supplementary Figure from Adenosine A2a Receptor Antagonism Restores Additive Cytotoxicity by Cytotoxic T Cells in Metabolically Perturbed Tumors

, 2023
Jeroen Slaats, Esther Wagena, Daan Smits, Annemarie A. Berends, Ella Peters, Gert‐Jan Bakker, Merijn van Erp, Bettina Weigelin, Gosse J. Adema, Peter Friedl   +9 more
openalex   +1 more source