Results 131 to 140 of about 34,994 (277)

Taurine alleviates dysfunction of cholesterol metabolism under hyperuricemia by inhibiting A2AR-SREBP-2/CREB/HMGCR axis

Journal of Lipid Research
Dysfunctional cholesterol metabolism is highly prevalent in patients with hyperuricemia. Both uric acid and cholesterol are independent risk factors for atherosclerosis, contributing to an increased incidence of cardiovascular disease in hyperuricemia ...
Beibei Chen, Ruixia Bao, Jujie Pan, Zicheng Zhu, Qian Chen, Dan Wang, Yuzheng Wu, Haiyang Yu, Yi Zhang, Tao Wang   +9 more
doaj   +1 more source

Pretreatment strategy with adenosine A2A receptor agonist attenuates reperfusion injury in a preclinical porcine lung transplantation model [PDF]

, 2011
Damien J. LaPar, Victor E. Laubach, Abbas Emaminia, Ivan K. Crosby, Vanessa A. Hajzus, Ashish K. Sharma, Heather M. Sumner, David V. Webb, Christine L. Lau, Irving L. Kron   +9 more
openalex   +1 more source

Lung Injury Pathways: Adenosine Receptor 2B Signaling Limits Development of Ischemic Bronchiolitis Obliterans Organizing Pneumonia [PDF]

, 2017
Purpose/Aim of the Study: Adenosine signaling was studied in bronchiolitis obliterans organizing pneumonia (BOOP) resulting from unilateral lung ischemia. Materials and Methods: Ischemia was achieved by either left main pulmonary artery or complete hilar
Auchampach, John, Audi, Said H., Densmore, John C., Dwinell, Melinda R., Geurts, Aron M., Jacobs, Elizabeth R., Jeziorczak, Paul M., Medhora, Meetha, Nayak, Shraddha, Schaid, Terry R.   +9 more
core   +1 more source

Adenosine A2A receptor availability in patients with early- and moderate-stage Parkinson’s disease [PDF]

, 2022
Imran Waggan, Eero Rissanen, Jouni Tuisku, Juho Joutsa, Semi Helin, Riitta Parkkola, Juha O. Rinne, Laura Airas   +7 more
openalex   +1 more source

Choroid Plexus-Selective Inactivation of Adenosine A2A Receptors Protects Against T Cell Infiltration And Experimental Autoimmune Encephalomyelitis [PDF]

, 2021
Wu Zheng, Yijia Feng, Zhenhai Zeng, Mengqian Ye, Huiping Shang, Mengru Wang, Xiangxiang Lin, Xiaoting Sun, Muran Wang, Zhengzheng Li, Yiyun Weng, Wei Guo, Serhii Vakal, Jiang‐Fan Chen   +13 more
openalex   +1 more source

Role of A₂A adenosine receptors on catecholamine release from mouse adrenal gland using a perfusion system [PDF]

, 2011
Dissertação de mestrado em Bioquímica, apresentada à Faculdade de Ciências e Tecnologia da Universidade de CoimbraAs glândulas supra-renais estão localizadas em cima de cada rim e são compostas por duas zonas funcionalmente distintas: a medula, ocupando
Vicente, Fábia Sofia Barata
core  

Adenosine A2A receptor blockade attenuates excitotoxicity in rat striatal medium spiny neurons during an ischemic-like insult

Neural Regeneration Research
During brain ischemia, excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage. Indeed, anoxic depolarization, consisting of massive neuronal depolarization due to the loss of membrane ion gradients, occurs in vivo ...
Elisabetta Coppi, Federica Cherchi, Alasdair J Gibb   +2 more
doaj   +1 more source

Supplementary Table from Phase Ia/b, Open-Label, Multicenter Study of AZD4635 (an Adenosine A2A Receptor Antagonist) as Monotherapy or Combined with Durvalumab, in Patients with Solid Tumors

, 2023
Emerson A. Lim, Johanna C. Bendell, Gerald S. Falchook, Todd M. Bauer, Charles G. Drake, Jennifer H. Choe, Daniel J. George, Janet L. Karlix, Susanna V. Ulahannan, Kris F. Sachsenmeier, Deanna L. Russell, Ganesh Moorthy, Ben S. Sidders, Elizabeth A. Pilling, Huifang Chen, Maureen M. Hattersley, Mayukh Das, Rakesh Kumar, Gayle P. Pouliot, Manish R. Patel   +19 more
openalex   +1 more source

Caffeine in cerebrovascular research: To withdraw or not to withdraw?

Experimental Physiology, Volume 111, Issue 2, Page 335-339, 1 February 2026.
Brooke R. Shepley, Kevin J. Milne, Anthony Richard Bain   +2 more
wiley   +1 more source

Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor

, 2011
Adam T. Waickman, Angela Alme, Liana Senaldi, Paul E. Zarek, Maureen R. Horton, Jonathan D. Powell   +5 more
openalex   +2 more sources