Results 111 to 120 of about 39,421 (210)

Exploring the Development of Vaccine Platforms, With a Particular Focus on the COVID‐19 Pandemic

Acta Paediatrica, Volume 115, Issue 11, Page 2421-2426, November 2026.
ABSTRACT Vaccines have been a cornerstone of human health for more than 200 years and one of the most important tools to reduce childhood deaths caused by pathogens. The concept of vaccines is basically to take something safe, make it immunogenic and induce an immune response in the host that will protect it against something dangerous. Live attenuated
Matti Sällberg
wiley   +1 more source

Increased Expression of Desmin and Vimentin Impairs Mitochondrial Function and Reduces Contractility via G0S2 in Bladder Smooth Muscle

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Our previous study demonstrated that elevated levels of desmin and vimentin reduce BSM contractility. This study shows that the reduced BSM contractility is associated with mitochondrial impairment. G0/G1 switch gene 2 (G0S2) is upregulated in desmin‐ and vimentin‐overexpressing BSM.
Elham Javed, Chellappagounder Thangavel, Karthik Thangavel, Joseph Hypolite, Isabelle Gamache, Yilin Wang, Sankar Addya, Darin Mak, Furqan Syed, Jyotsna Mishra, Vilas Desai, Pragnya Das, Dominic R. Villalba, Alok Bhushan, Shey‐Shing Sheu, Sunday A. Shoyele, Erin L. Seifert, Jose G. Teodoro, Steven S. An, Raymond B. Penn, Deepak A. Deshpande, Ettickan Boopathi   +21 more
wiley   +1 more source

Swapping the serotype: A novel helper-dependent adenoviral vector platform for in vivo HSC gene therapy. [PDF]

Mol Ther Methods Clin Dev, 2023
Klatt D, Brendel C, Bauer DE.
europepmc   +1 more source

Enhanced Immunogenicity and Cross-Neutralizing Activity of a Trivalent Adenoviral Vector-Based SARS-CoV-2 Vaccine in Mice. [PDF]

J Med Virol
Li J, Song W, Li J, Peng R, Chen C, Zhang Y, Zhu Y, Chen K.   +7 more
europepmc   +1 more source

Adenoviral Vector-Based Vaccine Platform for COVID-19: Current Status. [PDF]

Vaccines (Basel), 2023
Chavda VP, Bezbaruah R, Valu D, Patel B, Kumar A, Prasad S, Kakoti BB, Kaushik A, Jesawadawala M.   +8 more
europepmc   +1 more source

High adenoviral vector concentration can cause irreversible aggregation during CsCl gradient ultracentrifugation. [PDF]

Front Microbiol
Wu H, Mei YF.
europepmc   +1 more source

An Adenoviral Vector as a Versatile Tool for Delivery and Expression of miRNAs. [PDF]

Viruses, 2022
Scholz J, Weil PP, Pembaur D, Koukou G, Aydin M, Hauert D, Postberg J, Kreppel F, Hagedorn C.   +8 more
europepmc   +1 more source

Upstream process optimization and its critical role in chimpanzee adenoviral vector clinical drug development: lessons learned from VRON-0200 manufacturing. [PDF]

Front Bioeng Biotechnol
Haut LH, Bennett J, MacDonald P.
europepmc   +1 more source

Intranasally Delivered Adenoviral Vector Protects Chickens against Newcastle Disease Virus: Vaccine Manufacturing and Stability Assessments for Liquid and Lyophilized Formulations. [PDF]

Vaccines (Basel), 2023
Farnós O, Martins Fernandes Paes BC, Getachew B, Rourou S, Chaabene A, Gelaye E, Tefera TA, Kamen AA.   +7 more
europepmc   +1 more source

Red Blood Cell-Associated Features of Adenoviral Vector-Linked Venous Thrombosis. [PDF]

Int J Mol Sci
Park H, Bae ON, Choi S, Lee E, Chang J, Chung HY.   +5 more
europepmc   +1 more source