Results 1 to 10 of about 629,088 (301)

Research advances in replication-deficient viral vector vaccines

open access: yesFrontiers in Veterinary Science
In recent years, replication-deficient viral vector vaccines have attracted much attention in the field of vaccine research and development due to their high safety and immunogenicity.
Junna Wang   +5 more
doaj   +1 more source

An efficient CRISPR vector toolbox for engineering large deletions in Arabidopsis thaliana

open access: yesPlant Methods, 2018
Background Our knowledge of natural genetic variation is increasing at an extremely rapid pace, affording an opportunity to come to a much richer understanding of how effects of specific genes are dependent on the genetic background.
Rui Wu   +9 more
doaj   +1 more source

Genome Editing Method for the Anaerobic Magnetotactic Bacterium Desulfovibrio magneticus RS-1. [PDF]

open access: yes, 2018
Magnetosomes are complex bacterial organelles that serve as model systems for studying bacterial cell biology, biomineralization, and global iron cycling. Magnetosome biogenesis is primarily studied in two closely related Alphaproteobacteria of the genus
Grant, Carly R   +3 more
core  

A simple and efficient CRISPR/Cas9 system permits ultra-multiplex genome editing in plants

open access: yesCrop Journal
The development and maturation of the CRISPR/Cas genome editing system provides a valuable tool for plant functional genomics and genetic improvement.
Suting Wu   +13 more
doaj   +1 more source

Application of kDNA as a molecular marker to analyse Leishmania infantum diversity in Portugal.

open access: yes, 2006
Around the Mediterranean basin Leishmania infantum is an important parasite causing canine leishmaniasis and visceral and cutaneous clinical forms in both immunocompetent and immunocompromised humans.
Almeida, Ana   +6 more
core   +1 more source

AUTOLOGOUS STEM CELL-BASED GENE THERAPY OFFERS AN INNOVATIVE SOLUTION FOR TREATING INHERITED BLOOD CELLS DISORDERS

open access: yesJournal of Stem Cell Research and Tissue Engineering
Recent advancements in medical treatments, particularly gene therapy using hematopoietic stem cells (HSCs), have significantly impacted the treatment of inherited blood disorders.
Nurul Faudhan, Yayu Aisida
doaj   +1 more source

Dual population-based incremental learning for problem optimization in dynamic environments [PDF]

open access: yes, 2003
Copyright @ 2003 Asia Pacific Symposium on Intelligent and Evolutionary SystemsIn recent years there is a growing interest in the research of evolutionary algorithms for dynamic optimization problems since real world problems are usually dynamic, which ...
Yang, S, Yao, X
core   +1 more source

Properties and use of novel replication-competent vectors based on Semliki Forest virus

open access: yesVirology Journal, 2009
Background Semliki Forest virus (SFV) has a positive strand RNA genome and infects different cells of vertebrates and invertebrates. The 5' two-thirds of the genome encodes non-structural proteins that are required for virus replication and synthesis of ...
Lulla Valeria   +5 more
doaj   +1 more source

Genetic Targeting of Adenoviral Vectors

open access: yesMolecular Therapy, 2000
Krasnykh, V N   +2 more
openaire   +4 more sources

Fluorescently Labeled Adenovirus with pIX-EGFP for Vector Detection

open access: yesMolecular Imaging, 2004
Adenoviruses are extensively studied in terms of their use as gene therapy vectors and pathogenesis. These vectors have been targeted on both transcriptional and transductional levels to achieve cell-specific gene delivery.
Long P. Le   +5 more
doaj   +1 more source

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