Results 1 to 10 of about 317,910 (262)

Genetic modification of baculovirus expression vectors

Virologica Sinica, 2012
As a protein expression vector, the baculovirus demonstrates many advantages over other vectors. With the development of biotechnology, baculoviral vectors have been genetically modified to facilitate high level expression of heterologous proteins in both insect and mammalian cells.
Shu-fen, Li, Hua-lin, Wang, Zhi-hong, Hu, Fei, Deng   +3 more
openaire   +3 more sources

Geminiviruses and their application in biotechnology

Journal of Integrative Agriculture, 2017
Being a major class of single-stranded DNA viruses, geminiviruses are mostly studied due to their catastrophic infectious effect on crops. These DNA viruses are characteristic for their ability in quickly multiplying viral genetic materials without ...
Qiu-ying YANG, Bo DING, Xue-ping ZHOU
doaj   +1 more source

Simulating population genetics of pathogen vectors in changing landscapes: guidelines and application with Triatoma brasiliensis. [PDF]

PLoS Neglected Tropical Diseases, 2014
BACKGROUND:Understanding the mechanisms that influence the population dynamics and spatial genetic structure of the vectors of pathogens infecting humans is a central issue in tropical epidemiology.
Francois Rebaudo, Jane Costa, Carlos E Almeida, Jean-Francois Silvain, Myriam Harry, Olivier Dangles   +5 more
doaj   +1 more source

System of centromeric, episomal, and integrative vectors based on drug resistance markers for Saccharomyces cerevisiae

BioTechniques, 2006
Integrative, centromeric, and episomal plasmids are essential for easy, fast, and reliable genetic manipulation of yeast. We constructed a system of shuttle vectors based on the widely used plasmids of the pRS series.
Christof Taxis, Michael Knop
doaj   +1 more source

Malaria Control with Genetically Manipulated Insect Vectors

Science, 2002
At a recent workshop, experts discussed the benefits, risks, and research priorities associated with using genetically manipulated insects in the control of vector-borne diseases.
Alphey L., Beard C., Billingsley P., Coetzee M., CRISANTI, Andrea, Curtis C., Eggleston P., Godfray C., Hemingway J., Jacobs Lorena M., James A., Kafatos F., Mukwaya L., Paton M., Powell J., Schneider W., Scott T., Sina B., Sinkins S., Spielman A., Toure Y., Collins F., Sinden R.   +22 more
openaire   +4 more sources

Developing Universal Genetic Tools for Rapid and Efficient Deletion Mutation in Vibrio Species Based on Suicide T-Vectors Carrying a Novel Counterselectable Marker, vmi480. [PDF]

PLoS ONE, 2015
Despite that Vibrio spp. have a significant impact on the health of humans and aquatic animals, the molecular basis of their pathogenesis is little known, mainly due to the limited genetic tools for the functional research of genes in Vibrio.
Peng Luo, Xiangyan He, Qiuting Liu, Chaoqun Hu   +3 more
doaj   +1 more source

Applications and developments of gene therapy drug delivery systems for genetic diseases

Asian Journal of Pharmaceutical Sciences, 2021
Genetic diseases seriously threaten human health and have always been one of the refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA, antisense oligonucleotide, CRISPR/Cas9 system, plasmid DNA and miRNA have shown ...
Xiuhua Pan, Hanitrarimalala Veroniaina, Nan Su, Kang Sha, Fenglin Jiang, Zhenghong Wu, Xiaole Qi   +6 more
doaj   +1 more source

NDRG2 Drives DRP1 Phosphorylation to Promote the Progression of Pulmonary Hypertension

Frontiers in Bioscience-Landmark
Background: Pulmonary hypertension (PH) is a progressive disease characterized by obstructive pulmonary vascular remodeling, for which no curative therapies effectively reverse disease progression. This study investigated whether N-myc
Jiayong Luo, Jinyu Chang, Yi Liu, Yusang Shao, Yanyan Zhang, Yingru Zheng, Enfang Xiao, Yanqing Xie, Shuangshuang Tu, Haoxuan Lu, Wenming He   +10 more
doaj   +1 more source

Intracranial hemorrhage detection in 3D computed tomography images using a bi-directional long short-term memory network-based modified genetic algorithm

Frontiers in Neuroscience, 2023
IntroductionIntracranial hemorrhage detection in 3D Computed Tomography (CT) brain images has gained more attention in the research community. The major issue to deal with the 3D CT brain images is scarce and hard to obtain the labelled data with better ...
Jewel Sengupta, Robertas Alzbutas, Przemysław Falkowski-Gilski, Bożena Falkowska-Gilska   +3 more
doaj   +1 more source

Construction of Shati/Nat8l Plasmid Vectors, and Analysis of Mitochondrial Function Mediated by Shati/Nat8l Against Amyloid β Toxicity

Neuropsychopharmacology Reports
In Alzheimer's disease (AD), the accumulation of senile plaques composed of neurotoxic amyloid β (Aβ) is known to be one of the causes. Shati/Nat8l, a gene related to neuropsychiatric disorders, encodes an enzyme that biosynthesizes N‐acetyl aspartate ...
Miho Takakuwa, Naotaka Izuo, Kakeru Chino, Yusuke Yano, Jun Yokose, Yuki Shigetsura, Atsumi Nitta   +6 more
doaj   +1 more source