Results 31 to 40 of about 21,559 (113)

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Metagenomic detection of a wide variety of viruses from Vietnamese bats

International Journal of Infectious Diseases
Introduction: The species richness of tropical bats is astonishing, such as the diversity of bat-borne viruses. As bats are important reservoirs of zoonotic pathogens, we investigated the viruses found in Vietnamese bats. Methods: Overall, sixty-one bats
Dr Tamás Görföl, Gábor Endre Tóth, Dr Vuong Tan Tu, Dr Zsófia Lanszki, Dr Eszter Kaszab, Dr Krisztina Bali, Dr Krisztián Bányai, Dr Gábor Kemenesi   +7 more
doaj   +1 more source

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

Advanced Genetics, Volume 6, Issue 4, December 2025.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

The Transmissibility of the Human Skin Virome: Potential Forensic Implications

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
To robustly establish the forensic potential of the human skin virome, continuous research and investigation across diverse ethnic groups are necessary. This study evaluated the stability and transmissibility of the skin virome in Koreans. Our results show that the skin virome is stable over time and can be shared through contact with objects ...
Min‐Jeong Kim, Ji‐Ho Park, Yong‐Bin Eom   +2 more
wiley   +1 more source

Variations of the Virome in Raw and Treated Water: A One‐Year Follow‐Up at Six Different Drinking Water Treatment Plants

Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.
This paper describes monitoring of outgoing water from drinking water treatment plants, geographically spread over half of Sweden and sampled every other month for 1 year. We found differences in the virome from the different water sources from each plant as well as differences in virus size and seasonal variation, where we also could detect viruses in
Fredy Saguti, Hao Wang, Marianela Patzi Churqui, Timur Tunovic, Linda Holmer, Ämma Pettersson, Caroline Schleich, Britt‐Marie Pott, Olof Bergstedt, Kristina Nyström, Heléne Norder   +10 more
wiley   +1 more source

Virome analysis suggests deltacoronaviruses and picornaviruses as a probable cause of severe intestinal disease on three quail farms

Animal Microbiome
Background Quail farming is increasingly popular mainly due to higher market interest in meat and eggs. However, quails are susceptible to several common poultry viral infections, especially in intensive farming systems.
Urška Kuhar, Uroš Krapež, Brigita Slavec, Joško Račnik, Petra Šenica Kavčič, Urska Jamnikar-Ciglenecki   +5 more
doaj   +1 more source

Gut Virome: What's the Role in Irritable Bowel Syndrome?

Reviews in Medical Virology, Volume 35, Issue 6, November 2025.
ABSTRACT The gut virome, an integral but still poorly understood component of the gut microbiota, is emerging as an important player in the pathophysiology of irritable bowel syndrome (IBS). Recent evidence suggests that alterations in virome diversity and phage–bacteria interactions contribute to gut dysbiosis, immune modulation and gut barrier ...
Francesco Rettura, Christian Lambiase, Andrea Bottari, Fabio Filippini, Luca Giacomelli, Mauro Pistello, Massimo Bellini   +6 more
wiley   +1 more source

Promising Cancer Vaccine for Glioblastoma Therapy: A Focus on mRNA Vaccine

Cancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Background Glioblastoma (GBM) is an aggressive primary brain tumor with poor prognosis and low survival rates. Standard treatments, such as surgery and radiotherapy, are limited by tumor infiltration and resistance. To review current vaccine strategies for GBM, including peptide, virotherapy, cell‐based, and genetic vaccines, with a focus on ...
Sama Barati, Sahar Ghoflchi, Pejman Hosseinzadeh, Sobhan Pouramini, Hossein Hosseini, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut, Tuba Çiğdem Oğuzoğlu   +1 more
wiley   +1 more source

Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System

Advanced Science, Volume 12, Issue 25, July 3, 2025.
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao, Wanglu Li, Kaiyu He, Hongmei Wang, Yan Xu, Qun Wu, Liu Wang, Yao Nie   +7 more
wiley   +1 more source