Results 41 to 50 of about 21,651 (113)

Variations of the Virome in Raw and Treated Water: A One‐Year Follow‐Up at Six Different Drinking Water Treatment Plants

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 6, December 2025.
This paper describes monitoring of outgoing water from drinking water treatment plants, geographically spread over half of Sweden and sampled every other month for 1 year. We found differences in the virome from the different water sources from each plant as well as differences in virus size and seasonal variation, where we also could detect viruses in
Fredy Saguti   +10 more
wiley   +1 more source

Gut Virome: What's the Role in Irritable Bowel Syndrome?

open access: yesReviews in Medical Virology, Volume 35, Issue 6, November 2025.
ABSTRACT The gut virome, an integral but still poorly understood component of the gut microbiota, is emerging as an important player in the pathophysiology of irritable bowel syndrome (IBS). Recent evidence suggests that alterations in virome diversity and phage–bacteria interactions contribute to gut dysbiosis, immune modulation and gut barrier ...
Francesco Rettura   +6 more
wiley   +1 more source

Promising Cancer Vaccine for Glioblastoma Therapy: A Focus on mRNA Vaccine

open access: yesCancer Medicine, Volume 14, Issue 18, September 2025.
ABSTRACT Background Glioblastoma (GBM) is an aggressive primary brain tumor with poor prognosis and low survival rates. Standard treatments, such as surgery and radiotherapy, are limited by tumor infiltration and resistance. To review current vaccine strategies for GBM, including peptide, virotherapy, cell‐based, and genetic vaccines, with a focus on ...
Sama Barati   +5 more
wiley   +1 more source

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut   +1 more
wiley   +1 more source

Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System

open access: yesAdvanced Science, Volume 12, Issue 25, July 3, 2025.
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao   +7 more
wiley   +1 more source

Addressing the Health Risks Posed by Adenovirus: A Perspective on Strategies for Prevention and Management

open access: yesHealth Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background Adenovirus (AdV) is a non‐enveloped virus with a double‐stranded DNA genome that can infect the respiratory and gastrointestinal tracts, as well as cause conjunctivitis. The infection is influenced by the patient's age, environment, temperature, and immunocompromised individuals.
Taslima Jamal Urmi   +2 more
wiley   +1 more source

Virome of Australia’s most endangered parrot in captivity evidenced of harboring hitherto unknown viruses

open access: yesMicrobiology Spectrum
The detection of emerging infectious diseases (EIDs) within endangered animal populations is increasing rapidly because of many factors, such as anthropogenic influences and climate change. Their impacts can be extensive and may further contribute to the
Natalie Klukowski   +3 more
doaj   +1 more source

Mammal-infecting DNA viruses identified in lemurs and rodents in Madagascar mirror the evolutionary history of their hosts. [PDF]

open access: yesMicrob Genom
Paietta EN   +13 more
europepmc   +1 more source

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