Respiratory Viral Infections and the Tonsillar Transcriptome: An Exploratory Study
Clinical &Experimental Allergy, EarlyView.
Tanzeela Hanif +9 more
wiley +1 more source
One day of environment‐induced heat stress causes injury to the murine kidney
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths +3 more
wiley +1 more source
Synergistic antitumor efficacy of a decorin-carrying oncolytic adenovirus combined with chemotherapy in pancreatic cancer. [PDF]
Chen J +4 more
europepmc +1 more source
Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich +5 more
wiley +1 more source
Toxic epidermal necrolysis in a preschooler associated with adenovirus respiratory infection: A case report. [PDF]
Rendon-Salazar MJ +7 more
europepmc +1 more source
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu +7 more
wiley +1 more source
Circular RNAs: Unlocking new avenues in cardiometabolic disease management
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor +4 more
wiley +1 more source
In Vitro Evaluation of Virucidal Effect of Polysaccharides Extracted and Purified from <i>Arthrospira platensis</i> and <i>Dunaliella salina</i> on Human Adenovirus Type 5 in A549 Cells. [PDF]
Verani M +10 more
europepmc +1 more source
What's new? Oncolytic viruses are a promising immunotherapeutic approach against many malignancies. However, it is unclear whether repeated doses have improved therapeutic value or may trigger greater side effects, especially in patients with hepatocellular carcinoma whose liver is chronically damaged.
Karen J. Scott +10 more
wiley +1 more source

