Results 201 to 210 of about 210,480 (291)

GUTTED ADENOVIRUS VECTORS AND ADENOVIRUS BIOLOGY [PDF]

Molecular Therapy, 2001
openaire   +1 more source

Frequency, Burden and Pathogens of Acute Respiratory Illness in Very Preterm Infants During Infancy

Acta Paediatrica, EarlyView.
ABSTRACT Aim To describe the frequency, burden, and pathogen profile of acute respiratory illnesses (ARIs) in very preterm infants during the first year after neonatal intensive care unit (NICU) discharge. Methods Very preterm infants were followed prospectively (August 2015–January 2017) with monthly assessments of symptoms, medication use, and ...
Patricia De Gouveia Belinelo, Nada Townsi, Naomi R. Hemy, Chisha T. Sikazwe, David W. Smith, Benjamin Stoecklin, J. Jane Pillow, Graham L. Hall, Ingrid A. Laing, Shannon J. Simpson   +9 more
wiley   +1 more source

Whole-genome sequencing of adenovirus 41 directly from wastewater using nested overlapping PCR and MinION. [PDF]

Microbiol Spectr
Nusrat N, Meschke JS, Swanstrom R, Rodríguez RA.   +3 more
europepmc   +1 more source

Assessment of viral pathogen removal across wastewater treatment stages in a swine processing facility

Australian Veterinary Journal, EarlyView.
A swine abattoir wastewater treatment system in Queensland, Australia, was monitored over 6 months to assess the effectiveness of a pond‐based treatment system for the removal of viruses prior to irrigation reuse. Four viruses were tracked through the facility, from points of entry to the final treated effluent, to identify major sources of viral ...
W Ahmed, M Gebrewold, WJM Smith, K Richards, SL Simpson   +4 more
wiley   +1 more source

Recombinant adenoviruses application for cancer vaccines: from genetic design to clinical translation. [PDF]

Front Oncol
Almarghalani NA, Ganash MA, Alharbi MG, Abualfaraj T, Alkayyal AA, Mahmoud AB.   +5 more
europepmc   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

British Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi, Nandakumar Natarajan, Kathryn E. Dickerson, Richard A. Voit   +3 more
wiley   +1 more source

A generalizable covalent car-t platform for solid tumors enabled by oncolytic adenovirus-delivered artificial antigens. [PDF]

Front Immunol
Guo L, Xie H, Yin D, Zhu G, Zhai P, Pei G, Zhang W, Xiao F, Lyu J, Tang D.   +9 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Severe adenovirus-associated pneumonia complicated by biopsy-evaluated acute kidney injury in an immunocompetent adult: a case report. [PDF]

BMC Nephrol
Şensoy NNÖ, Ayar Y.
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source