Results 221 to 230 of about 281,343 (303)

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

open access: yes
Vox Sanguinis, EarlyView.
Pierre Tiberghien   +4 more
wiley   +1 more source

Distinct Roles of Myeloid‐ and Hepatocyte‐PLA2G6 Deletion in Mice With Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Polymorphisms of group VIA calcium‐independent phospholipase A2 (iPLA2β or PLA2G6) are associated with Type‐2 diabetes, blood lipids and inflammation. Global deficiency in iPLA2β‐null mice elicited protection against hepatic steatosis but not hepatic inflammation after high‐fat diet (HFD) feeding.
Gang Li   +4 more
wiley   +1 more source

Association Between Point-of-Care Viral Testing for Influenza and Adenovirus and Antibiotic Management in a Pediatric Emergency Department in Italy. [PDF]

open access: yesChildren (Basel)
Bellini T   +12 more
europepmc   +1 more source

The E3 Ligase RNF8 Promotes Ubiquitination and Degradation of ChREBPα During Liver Stress Response

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
During MASH development, increasing hepatic stress signals, particularly a combination of lipotoxicity (palmitate) and inflammation (TNFα), trigger JNK, the key stress‐activated protein kinase. Activated JNK recruits RNF8, a stress‐induced E3 ligase, to promote ubiquitination and proteasomal degradation of the ChREBPα protein.
Yuee Zhao   +8 more
wiley   +1 more source

Prostate cancer associated 3 (PCA3) is a potential indicator of the pathological grades of prostate cancer. [PDF]

open access: yesDiscov Oncol
Guo Y   +9 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, Volume 16, Issue 5, Page 857-869, May 2026.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Fowl adenovirus infection and inclusion body hepatitis in Canada: genotyping trends from 2008 to 2024. [PDF]

open access: yesJ Vet Diagn Invest
Ojkić D   +7 more
europepmc   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz   +11 more
wiley   +1 more source

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