Results 321 to 330 of about 314,751 (339)
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Journal of Molecular Biology, 1973
Abstract End fragments of molecular weight 1 to 2.5 × 10 6 were prepared from the DNA molecules of human adenovirus 2 and simian adenovirus SA-7. These end pieces were shown by DNA-DNA hybridization to contain only 15 to 30% of the sequences present in the entire genome.
Robbet B. Murray, Maurice Green
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Abstract End fragments of molecular weight 1 to 2.5 × 10 6 were prepared from the DNA molecules of human adenovirus 2 and simian adenovirus SA-7. These end pieces were shown by DNA-DNA hybridization to contain only 15 to 30% of the sequences present in the entire genome.
Robbet B. Murray, Maurice Green
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Endocytosis of adenovirus and adenovirus capsid proteins
Advanced Drug Delivery Reviews, 2003Key proteins of the icosahedral-shaped adenovirus (Ad) capsid mediate infection, and interact with cellular proteins to coordinate stepwise events of cell entry that produce successful gene transfer. Infection is mediated predominantly by the penton and fiber capsid proteins. The fiber initiates cell binding while the penton binds integrin coreceptors,
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Human Gene Therapy, 2004
Structural studies continue to play an essential role as the focus of adenovirus research shifts in emphasis from basic biology to adenovirus-based vector technologies. A crucial step in developing novel therapeutics for gene replacement, cancer, and vaccines is often to modify the virion.
John J, Rux, Roger M, Burnett
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Structural studies continue to play an essential role as the focus of adenovirus research shifts in emphasis from basic biology to adenovirus-based vector technologies. A crucial step in developing novel therapeutics for gene replacement, cancer, and vaccines is often to modify the virion.
John J, Rux, Roger M, Burnett
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Adenovirus Meningoencephalitis
Pediatrics, 1978Central nervous system manifestations in association with adenovirus infections have rarely been documented. In this report, four children, ages 4, 5, 6, and 10 years, with adenoviral meningoencephalitis are described. Adenoviruses were recovered from CSF specimens in all four patients.
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Human Gene Therapy, 2004
Recombinant adenovirus (Ad) vectors continue to be the preferred vectors for gene therapy and the study of gene function because they are relatively easy to construct, can be produced at high titer, and have high transduction efficiency. However, in some applications gene transfer with Ad vectors is less efficient because the target cells lack ...
Hiroyuki Mizuguchi, Takao Hayakawa
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Recombinant adenovirus (Ad) vectors continue to be the preferred vectors for gene therapy and the study of gene function because they are relatively easy to construct, can be produced at high titer, and have high transduction efficiency. However, in some applications gene transfer with Ad vectors is less efficient because the target cells lack ...
Hiroyuki Mizuguchi, Takao Hayakawa
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2008
Adenoviruses are associated with numerous disease outbreaks, particularly those involving d-cares, schools, children's camps, hospitals and other health care centers, and military settings. In addition, adenoviruses have been responsible for many recreational water outbreaks, including a great number of swimming pool outbreaks than any other waterborne
Kristina D, Mena, Charles P, Gerba
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Adenoviruses are associated with numerous disease outbreaks, particularly those involving d-cares, schools, children's camps, hospitals and other health care centers, and military settings. In addition, adenoviruses have been responsible for many recreational water outbreaks, including a great number of swimming pool outbreaks than any other waterborne
Kristina D, Mena, Charles P, Gerba
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The Coxsackievirus and Adenovirus Receptor
2008The coxsackievirus and adenovirus receptor (CAR) has been studied extensively since its identification and isolation in 1997. The CAR is an immunoglobulin superfamily protein with two extracellular Ig-like domains, a single membrane-spanning sequence, and a significant cytoplasmic domain.
Louis H. Philipson +2 more
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ADENOVIRUS AND INTUSSUSCEPTION [PDF]
Medical Journal of Australia, 1966 David O. White, John E. Solomon
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2002
Publisher Summary This chapter discusses the structural components of the adenovirus. MALDI-TOF mass spectroscopy has confirmed the predicted protease cleavage sites of several structural proteins. The use of phage-display libraries has pinpointed the residues involved in the interaction between penton base and fiber.
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Publisher Summary This chapter discusses the structural components of the adenovirus. MALDI-TOF mass spectroscopy has confirmed the predicted protease cleavage sites of several structural proteins. The use of phage-display libraries has pinpointed the residues involved in the interaction between penton base and fiber.
openaire +3 more sources