Results 51 to 60 of about 115,226 (275)

Immune status affects the clinical features and outcomes of adult patients with respiratory adenovirus infection [PDF]

, 2021
Handan Zhao, Minghan Zhou, Qing Zheng, Guanjing Lang, Lijun Xu   +4 more
openalex   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Characteristics and Indications of Kawasaki Disease Among Infants Under 6 Months

Frontiers in Pediatrics, 2020
Objectives: To explore the characteristics of Kawasaki disease (KD) under 6 months and to investigate the possible indications of incomplete KD (iKD).Methods: The medical records of KD patients hospitalized in Children's Hospital of Soochow University ...
Yunjia Tang, Xuan Li, Lei Cao, Ye Chen, Wenhua Yan, Qiuqin Xu, Haitao Lv   +6 more
doaj   +1 more source

Distribution of Adenovirus and Rotavirus by Age and Seasons in Children Diagnosed with Viral Gastroenteritis

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: This study aimed to analyze the distribution of rotavirus and adenovirus in pediatric patients according to the age and seasons of infection.
Yakup Çağ, Demet Hacıseyitoğlu
doaj   +1 more source

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source

Disseminated adenovirus infection in a 10-year-old renal allograft recipient

Kidney Research and Clinical Practice, 2018
Disseminated adenovirus infection can result in high mortality and morbidity in immunocompromised patients. Here, we report the case of a 10-year-old renal allograft recipient who presented with hematuria and dysuria.
Bora Lee, Eujin Park, Jongwon Ha, Il Soo Ha, Hae Il Cheong, Hee Gyung Kang   +5 more
doaj   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source

Immuno-morphological aspects of the pathogenesis iga-nephropathy in patients with adenovirus infection with regard to age

Журнал инфектологии, 2014
In recent years, examines the role of viral infection in the development of IgA-nephropathy. In our study, an analysis of renal biopsy tissue from 17 patients IgA-nephropathy in the presence of adenoviral antigen.
I. A. Rakityanskaya, T. S. Ryabova
doaj   +1 more source

Adenovirus Infection in Spanish Ibex [PDF]

Journal of Veterinary Diagnostic Investigation, 1998
domestic animals, 4th ed., pp. 438–441. Academic Press, New York, NY. 10. Li X, Scott FW: 1994, Detection of feline coronaviruses in cell cultures and in fresh and fixed feline tissues using polymerase chain reaction. Vet Microbiol 42:65–77. 11. Pedersen NC: 1987, Virologic and immunologic aspects of feline infectious peritonitis virus infection.
J, Hervás, S, López, F, Chacón-M de Lara, J, Arias, L, Carrasco, J C, Gómez-Villamandos   +5 more
openaire   +2 more sources