Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation [PDF]
NKG2D plays a major role in controlling immune responses through the regulation of natural killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct ligands (the MHC Class I polypeptide-related sequences (MIC) A ...
A Dolan +98 more
core +6 more sources
Abortive Infection of Human Cell Cultures by a Canine Adenovirus
SummaryThe abortive infection of human amnion cells by infectious canine hepatitis virus (ICHV) was studied. Within 48 hr after inoculation, large quantities of complement fixing (CF) antigen were produced, although infectious virus yields were small.
W D, Gehle, K O, Smith
openaire +2 more sources
Human adenoviruses (HAd) cause respiratory, gastrointestinal and ocular infections. Here, the authors provide insights into the early stages of adenovirus infection by determining the cryo-EM structure of the trimeric HAd type 3 fibre knob bound to its ...
Emilie Vassal-Stermann +8 more
doaj +1 more source
Attempts to Infect Rhesus Monkeys with Human Type 4 Adenovirus
SummaryIn searching for an animal model for human adenovirus studies we have attempted to infect rhesus monkeys with a human type 4 adenovirus. The results were inconclusive but we have some evidence to suggest that infection and replication might have occurred in several animals. Communicability among cagemates was not demonstrated.
F A, Pedreira +4 more
openaire +2 more sources
Human adenoviruses comprise an important group of etiologic agents that are responsible for various diseases in adults and children, such as respiratory, ocular, gastroenteric, and urinary infections.
Inarei Paulini +6 more
doaj +1 more source
DO IT Trial: vitamin D Outcomes and Interventions in Toddlers - a TARGet Kids! randomized controlled trial. [PDF]
BackgroundVitamin D levels are alarmingly low (<75 nmol/L) in 65-70% of North American children older than 1 year. An increased risk of viral upper respiratory tract infections (URTI), asthma-related hospitalizations and use of anti-inflammatory ...
Birken, Catherine S +10 more
core +3 more sources
Probable Donor-Derived Human Adenovirus Type 34 Infection in 2 Kidney Transplant Recipients From the Same Donor. [PDF]
Human adenovirus type 34 (HAdV-34) infection is a recognized cause of transplant-associated hemorrhagic cystitis and, in rare cases, tubulointerstitial nephritis.
Babu, Tara M. +9 more
core +1 more source
Adenovirus type 5 E4 Orf3 protein targets promyelocytic leukaemia (PML) protein nuclear domains for disruption via a sequence in PML isoform II that is predicted as a protein interaction site by bioinformatic analysis [PDF]
Human adenovirus type 5 infection causes the disruption of structures in the cell nucleus termed promyelocytic leukaemia (PML) protein nuclear domains or ND10, which contain the PML protein as a critical component. This disruption is achieved through the
Araujo +37 more
core +1 more source
Molecular Survey of Viral and Bacterial Causes of Childhood Diarrhea in Khartoum State, Sudan
Diarrheal disease is a major public health problem for children in developing countries. Knowledge of etiology that causes diarrheal illness is essential to implement public health measures to prevent and control this disease. Published studies regarding
Mosab A. Adam +11 more
doaj +1 more source
Corticosteroids for the common cold [PDF]
BACKGROUND: The common cold is a frequent illness, which, although benign and self limiting, results in many consultations to primary care and considerable loss of school or work days. Current symptomatic treatments have limited benefit.
Del Mar, Chris B. +5 more
core +1 more source

