Results 31 to 40 of about 45,608 (300)

Detection of DNA Viruses in Free-Ranging Rat Populations in Hungary

Viruses
To address a gap in our understanding of viral infections in epidemiologically important rat species, we aimed to detect DNA viruses from the tissues of free-ranging rat populations in Hungary.
Márton Z. Vidovszky, András Surján, Gábor Földvári, László Egyed   +3 more
doaj   +1 more source

A case of severe acute hepatitis of unknown etiology requiring liver transplantation in a child with adenovirus infection

Журнал инфектологии, 2022
The article presents a clinical observation of severe acute hepatitis of unknown aetiology with liver transplantation in a 16-year-old child, which occurred in October 2021. Initial symptoms were abdominal pain, diarrhea.
V. A. Greshnyakova, M. K. Bekhtereva, L. G. Goryacheva, V. E. Karev, A. M. Komarova, A. I. Konev, Yu. V. Lobzin, A. N. Uskov, N. V. Skripchenko, K. V. Serednyakov   +9 more
doaj   +1 more source

Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells [PDF]

, 2006
Swiss Cancer League, Swiss National Science Foundation and SNSF NCCR Molecular Oncology ProgrammeBackground: The Wnt signaling pathway is activated by mutations in the APC and beta-catenin genes in many types of human cancer.
Homicsko, Krisztian, Pittet Anne-Laure, Christophe Fuerer, Lukashev, Alexander N., Homicsko Krisztian, Alexander N Lukashev, Fuerer Christophe, Anne-Laure Pittet, Iggo, Richard D., Fuerer, Christophe, Pittet, Anne-Laure, Richard D Iggo, Lukashev Alexander N, Iggo Richard D, Krisztian Homicsko   +14 more
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Household Transmission of Human Adenovirus Type 55 in Case of Fatal Acute Respiratory Disease

Emerging Infectious Diseases, 2019
We identified a case of fatal acute respiratory disease from household transmission of human adenovirus type 55 (HAdV-55) in Anhui Province, China. Computed tomography showed severe pneumonia.
Shuping Jing, Jing Zhang, Mengchan Cao, Minhong Liu, Yuqian Yan, Shan Zhao, Na Cao, Junxian Ou, Kui Ma, Xiangran Cai, Jianguo Wu, Ya-Fang Mei, Qiwei Zhang   +12 more
doaj   +1 more source

Intracellular Sequestration of the NKG2D Ligand MIC B by Species F Adenovirus

Viruses, 2021
The enteric human adenoviruses of species F (HAdVs-F), which comprise HAdV-F40 and HAdV-F41, are significant pathogens that cause acute gastroenteritis in children worldwide.
Edson R. A. Oliveira, Lenong Li, Marlene Bouvier   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Surveillance for adenoviruses in bats in Italy [PDF]

, 2019
Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans.
Prosperi A., Lanave G., Chiapponi C., Lelli D., Sozzi E., Decaro N., Martella V., Lavazza A., Diakoudi G., Larocca V., Moreno A., Losurdo M.   +11 more
core   +2 more sources

TRIM56 enhances adenoviral E1A steady state to improve oncolytic adenovirus therapy efficacy

Journal of Virology
Oncolytic adenoviruses (OAVs) engineered to carry antitumor or immune-activating transgenes are being actively explored for cancer immunotherapy. While many efforts have focused on modifying OAVs to counteract the immunosuppressive tumor microenvironment,
Nan Sun, Jikai Zhang, Chen Zhang, Hang Yin, Botao Zou, Yunfeng Geng, Wanjun Gao, Yuxin Zhang, Gang Wang, Junnian Zheng, Lin Fang   +10 more
doaj   +1 more source

Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR)

mBio, 2019
Protein kinase R (PKR) plays a major role in activating host immunity during infection by sensing double-stranded RNA (dsRNA) produced by viruses. Once activated by dsRNA, PKR phosphorylates the translation factor eukaryotic initiation factor 2α (eIF2α),
Danielle E. Goodman, Carla D. Pretto, Tomas A. Krepostman, Kelly E. Carnahan, Katherine R. Spindler   +4 more
doaj   +1 more source