Oncolytic viruses for cancer immunotherapy [PDF]
Journal of Hematology & Oncology, 2020 In this review, we discuss the use of oncolytic viruses in cancer immunotherapy treatments in general, with a particular focus on adenoviruses. These serve as a model to elucidate how versatile viruses are, and how they can be used to complement other ...
Otto Hemminki +2 more
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Recent advances in oncolytic virus therapy for hepatocellular carcinoma
Frontiers in Oncology, 2023 Hepatocellular carcinoma (HCC) is a highly refractory cancer and the fourth leading cause of cancer-related mortality worldwide. Despite the development of a detailed treatment strategy for HCC, the survival rate remains unsatisfactory.
Licheng Zhu +14 more
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Application progress of oncolytic virus combined with immunotherapy in the treatment of malignant tumors [PDF]
Zhongguo aizheng zazhiThe oncolytic virus (OV) therapy utilizes natural or genetically modified viruses to specifically target and infect tumor cells, leading to the destruction of cancer cells by the replication of the virus itself.
LIANG Yingyun, CHEN Jianhua
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Tumor Tropism of DNA Viruses for Oncolytic Virotherapy
Viruses, 2023 Oncolytic viruses (OVs) have emerged as one of the most promising cancer immunotherapy agents that selectively target and kill cancer cells while sparing normal cells. OVs are from diverse families of viruses and can possess either a DNA or an RNA genome.
Junior A. Enow +2 more
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CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses
Viruses, 2016 The development of oncolytic viruses has led to an emerging new class of cancer therapeutics. Although the safety profile has been encouraging, the transition of oncolytic viruses to the clinical setting has been a slow process due to modifications ...
Ming Yuan +3 more
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Oncolytic Viruses for Malignant Glioma: On the Verge of Success?
Viruses, 2021 Glioblastoma is one of the most difficult tumor types to treat with conventional therapy options like tumor debulking and chemo- and radiotherapy.
Yogesh R. Suryawanshi, Autumn J. Schulze
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Biological therapy in the treatment of melanoma [PDF]
, 2018 Melanoma is one of the most aggressive tumors and its incidence is on the rise. The low rates of survival in metastatic melanoma has led to the development of new drugs for this type of patient, such as biological therapy which has shown remarkable ...
Benea, Vasile +8 more
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The essential role of mitochondrial dynamics in antiviral immunity. [PDF]
, 2018 Viruses alter cellular physiology and function to establish cellular environment conducive for viral proliferation. Viral immune evasion is an essential aspect of viral persistence and proliferation.
Ahn, Dae-Gyun +3 more
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Oncolytic effects of a novel influenza A virus expressing interleukin-15 from the NS reading frame. [PDF]
PLoS ONE, 2012 Oncolytic influenza A viruses with deleted NS1 gene (delNS1) replicate selectively in tumour cells with defective interferon response and/or activated Ras/Raf/MEK/ERK signalling pathway.
Marijke van Rikxoort +7 more
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Comprehensive assessment on the applications of oncolytic viruses for cancer immunotherapy
Frontiers in Pharmacology, 2022 The worldwide burden of cancers is increasing at a very high rate, including the aggressive and resistant forms of cancers. Certain levels of breakthrough have been achieved with the conventional treatment methods being used to treat different forms of ...
Richard Kolade Omole +14 more
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